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Single molecule FRET (fluorescence resonance energy transfer) is a powerful technique for detecting real-time conformational changes and molecular interactions during biological reactions. In this review, we examine different techniques of…

Biomolecules · Quantitative Biology 2007-05-23 Ivan Rasnik , Sean A. McKinney , Taekjip Ha

We analyze quantum interference and decoherence effects in single-molecule junctions both experimentally and theoretically by means of the mechanically controlled break junction technique and density-functional theory. We consider the case…

Mesoscale and Nanoscale Physics · Physics 2012-09-26 Stefan Ballmann , Rainer Härtle , Pedro B. Coto , Marcel Mayor , Mark Elbing , Martin R. Bryce , Michael Thoss , Heiko B. Weber

Time course measurement of single molecules on a cell surface provides detailed information on the dynamics of the molecules, which is otherwise inaccessible. To extract the quantitative information, single particle tracking (SPT) is…

Quantitative Methods · Quantitative Biology 2016-01-06 Shunsuke Teraguchi , Yutaro Kumagai

This paper explores the entanglement dynamics generated by interacting two-particle quantum walks on degree-regular and -irregular graphs. We performed spectral analysis of the time-evolution of both the particle probability distribution…

Quantum Physics · Physics 2015-11-17 G. R. Carson , T. Loke , J. B. Wang

In a stochastic reaction network setting we consider the problem of tracking the fate of individual molecules. We show that using the classical large volume limit results, we may approximate the dynamics of a single tracked molecule in a…

Probability · Mathematics 2023-01-05 Daniele Cappelletti , Grzegorz A. Rempala

We derive approximate equations of motion for excited state dynamics of a multilevel open quantum system weakly interacting with light to describe fluorescence detected single molecule spectra. Based on the Frenkel exciton theory, we…

Biological Physics · Physics 2015-12-04 Pavel Malý , J. Michael Gruber , Rienk van Grondelle , Tomáš Mančal

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

Light-matter interaction dynamics is governed by the strength of local coupling constants, tailored by surrounding electromagnetic structures. Characteristic decay times in dipole-allowed fluorescent transitions are much faster than…

We present a new physical model resolving a long-standing mystery of the power-law distributions of the blinking times in single colloidal quantum dot fluorescence. The model considers the non-radiative relaxation of the exciton through…

Statistical Mechanics · Physics 2009-11-16 Pavel A. Frantsuzov , Sandor Volkan-Kacso , Bolizsar Janko

Quantitative fluorescence analysis is often used to derive chemical properties, including stoichiometries, of biomolecular complexes. One fundamental underlying assumption in the analysis of fluorescence data -- whether it be the…

Chemical Physics · Physics 2022-04-22 Ayush Saurabh , Stefan Niekamp , Ioannis Sgouralis , Steve Pressé

The full information about the interaction between a quantum emitter and an arbitrary electromagnetic environment is encoded in the so-called spectral density. We present an approach for describing such interaction in any coupling regime,…

Quantum Physics · Physics 2024-07-02 Carlos J. Sánchez Martínez , Johannes Feist , Francisco J. García-Vidal

In this paper, single-molecule spectroscopy experiments based on continuous laser excitation are characterized through an open quantum system approach. The evolution of the fluorophore system follows from an effective Hamiltonian…

Quantum Physics · Physics 2009-04-09 Adrian A. Budini

We extend the generating function technique for calculation of single molecule photon emission statistics [Y. Zheng and F. L. H. Brown, Phys. Rev. Lett., 90,238305 (2003)] to systems governed by multi-level quantum dynamics. This opens up…

Materials Science · Physics 2009-09-18 Golan Bel , Yujun Zheng , Frank L. H. Brown

Fluorescence spectroscopy is an image correlation technique to analyze and characterize the molecular dynamics from a sequence of fluorescence images. Many image correlation techniques have been developed for different applications [1]. But…

Quantitative Methods · Quantitative Biology 2017-10-24 C. Chen , P. Paul-Gilloteaux , T. Vignaud , J. Salamero , F. Waharte

We study the effects of interatomic interactions on the quantum dynamics of a dense, nanoscale, atomic ensemble driven by a strong electromagnetic field. We use a self-consistent, mean-field technique based on the pseudo-spectral…

Quantum Physics · Physics 2018-01-17 C. S. DiLoreto , C. Rangan

A discrete binomial random-walk description of molecular collisions is used to quantify the variance of coarse-grained velocity fields arising solely from collision-induced momentum exchange. Closed-form expressions for the growth of…

Chemical Physics · Physics 2026-02-26 Tristan Barkman

We investigate continuous-time quantum walks of two indistinguishable particles (bosons, fermions or hard-core bosons) in one-dimensional lattices with nearest-neighbour interactions. The two interacting particles can undergo independent-…

Quantum Physics · Physics 2014-02-17 Xizhou Qin , Yongguan Ke , Xiwen Guan , Zhibing Li , Natan Andrei , Chaohong Lee

Using a quantum electrodynamic framework, we calculate the off-resonant scattering of a broad-band X-ray pulse from a sample initially prepared in an arbitrary superposition of electronic states. The signal consists of single-particle…

Chemical Physics · Physics 2015-06-19 Kochise Bennett , Jason D. Biggs , Yu Zhang , Konstantin E. Dorfman , Shaul Mukamel

We study theoretically the quantum optical properties of hybrid molecules composed of an individual quantum dot and a metallic nanoparticle. We calculate the resonance fluorescence of this hybrid system. Its incoherent part, the one arising…

Quantum Physics · Physics 2010-04-12 A. Ridolfo , O. Di Stefano , N. Fina , R. Saija , S. Savasta