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Infectious disease outbreaks can have a disruptive impact on public health and societal processes. As decision making in the context of epidemic mitigation is hard, reinforcement learning provides a methodology to automatically learn…

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

The COVID-19 pandemic underscored a critical need for intervention strategies that balance disease containment with socioeconomic stability. We approach this challenge by designing a framework for modeling and evaluating disease-spread…

Machine Learning · Computer Science 2025-10-07 Marian Chen , Miri Zilka

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no…

Applications · Statistics 2020-09-08 Se Yoon Lee , Bowen Lei , Bani K. Mallick

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

Physics and Society · Physics 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

Machine Learning · Computer Science 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

The COronaVIrus Disease 2019 (COVID-19) pandemic that has had the world in its grip from the beginning of 2020, has resulted in an unprecedented level of public interest and media attention on the field of mathematical epidemiology. Ever…

Other Quantitative Biology · Quantitative Biology 2022-03-25 Sitabhra Sinha

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

Machine Learning · Computer Science 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

This paper presents a real time, data driven decision support framework for epidemic control. We combine a compartmental epidemic model with sequential Bayesian inference and reinforcement learning (RL) controllers that adaptively choose…

Methodology · Statistics 2025-11-25 Giacomo Iannucci , Petros Barmpounakis , Alexandros Beskos , Nikolaos Demiris

Accurate forecasting of infectious disease incidence is critical for public health planning and timely intervention. While most data-driven forecasting approaches rely primarily on historical data from a single country, such data are often…

Populations and Evolution · Quantitative Biology 2026-01-29 Zacharias Komodromos , Kleanthis Malialis , Artemis Kontou , Panayiotis Kolios

Controlling infectious diseases is a major health priority because they can spread and infect humans, thus evolving into epidemics or pandemics. Therefore, early detection of infectious diseases is a significant need, and many researchers…

Machine Learning · Computer Science 2022-06-16 Eman Yahia Alqaissi , Fahd Saleh Alotaibi , Muhammad Sher Ramzan

The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we…

Accurate forecasts of COVID-19 is central to resource management and building strategies to deal with the epidemic. We propose a heterogeneous infection rate model with human mobility for epidemic modeling, a preliminary version of which we…

Populations and Evolution · Quantitative Biology 2020-05-06 Ajitesh Srivastava , Viktor K. Prasanna

Balancing common disease treatment and epidemic control is a key objective of medical supplies procurement in hospitals during a pandemic such as COVID-19. This problem can be formulated as a bi-objective optimization problem for…

Neural and Evolutionary Computing · Computer Science 2020-08-04 Yu-Jun Zheng , Xin Chen , Tie-Er Gan , Min-Xia Zhang , Wei-Guo Sheng , Ling Wang

During an infectious disease outbreak, policymakers must balance medical costs with social and economic burdens and seek interventions that minimize both. To support this decision-making process, we developed a framework that integrates…

Optimization and Control · Mathematics 2026-04-03 Jongmin Lee , Renier Mendoza , Victoria May P. Mendoza , Eunok Jung

Epidemic modeling, encompassing deterministic and stochastic approaches, is vital for understanding infectious diseases and informing public health strategies. This research adopts a prescriptive approach, focusing on reinforcement learning…

Artificial Intelligence · Computer Science 2023-12-27 Elizabeth Akinyi Ondula , Bhaskar Krishnamachari

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

Populations and Evolution · Quantitative Biology 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

The COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies.…

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