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Computer modelling for evolutionary systems consists in: 1) to store in the memory the individual features of each member of a large population; and 2) to update the whole system repeatedly, as time goes by, according to some prescribed…

Statistical Mechanics · Physics 2007-05-23 Paulo Murilo Castro de Oliveira

This white paper lays out a vision of research and development in the field of artificial intelligence for the next decade (and beyond). Its denouement is a cyber-physical ecosystem of natural and synthetic sense-making, in which humans are…

System and synthetic biology are rapidly evolving systems, but both lack tools such as those used in engineering environments to shift the their focus from the design of parts (details) to the design of systems (behaviors); to aggravate,…

Emerging Technologies · Computer Science 2015-07-29 Ricardo Henrique Gracini Guiraldelli , Vincenzo Manca

Bio-digital systems that merge microbial life with technology promise new modes of computation, combining biological adaptability with digital precision. Yet realizing this potential symbiotically -- where biological and digital agents…

Human-Computer Interaction · Computer Science 2026-01-23 Zoë Breed , Elvin Karana , Alessandro Bozzon , Katherine W. Song

More than hundred years ago the 'classic physics' was it in its full power, with just a few unexplained phenomena; which however led to a revolution and the development of the 'modern physics'. Today the computing is in a similar position:…

General Literature · Computer Science 2020-01-07 János Végh

Social evolutionary theory seeks to explain increases in the scale and complexity of human societies, from origins to present. Over the course of the twentieth century, social evolutionary theory largely fell out of favor as a way of…

Multiagent Systems · Computer Science 2025-02-27 David H. Wolpert , Kyle Harper

This work concerns a many-body deterministic model that displays life-like properties as emergence, complexity, self-organization, spontaneous compartmentalization, and self-regulation. The model portraits the dynamics of an ensemble of…

Adaptation and Self-Organizing Systems · Physics 2023-07-11 Alessandro Scirè , Valerio Annovazzi-Lodi

This philosophical paper explores the relation between modern scientific simulations and the future of the universe. We argue that a simulation of an entire universe will result from future scientific activity. This requires us to tackle…

Artificial Intelligence · Computer Science 2008-12-02 Clement Vidal

I describe my path to unconventionality in my exploration of theoretical and applied aspects of computation towards revealing the algorithmic and reprogrammable properties and capabilities of the world, in particular related to applications…

General Literature · Computer Science 2017-06-28 Hector Zenil

Computational models are invaluable in capturing the complexities of real-world biological processes. Yet, the selection of appropriate algorithms for inference tasks, especially when dealing with real-world observational data, remains a…

Applications · Statistics 2024-10-01 Xiaoyu Wang , Ryan P. Kelly , Adrianne L. Jenner , David J. Warne , Christopher Drovandi

The cells and tissues that make up our body juggle contradictory mechanical demands. It is crucial for their survival to be able to withstand large mechanical loads, but it is equally crucial for them to produce forces and actively change…

Biological Physics · Physics 2019-03-22 Federica Burla , Yuval Mulla , Bart E. Vos , Anders Aufderhorst-Roberts , Gijsje H. Koenderink

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

Quantitative Methods · Quantitative Biology 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

Interactions with large language models have led to the suggestion that these models may soon be conscious. From the perspective of neuroscience, this position is difficult to defend. For one, the inputs to large language models lack the…

Neurons and Cognition · Quantitative Biology 2023-08-29 Jaan Aru , Matthew Larkum , James M. Shine

Fermions are fundamental particles which obey seemingly bizarre quantum-mechanical principles, yet constitute all the ordinary matter that we inhabit. As such, their study is heavily motivated from both fundamental and practical incentives.…

Quantum Physics · Physics 2023-12-19 Andrew Zhao

Artificial computing machinery transforms representations through an objective process, to be interpreted subjectively by humans, so the machine and the interpreter are different entities, but in the putative natural computing both…

Artificial Intelligence · Computer Science 2025-06-17 Luis A. Pineda

From a purely operational standpoint, the existence of microbes that can grow under extreme conditions, or "extremophiles", leads to the question of how the molecules making up these microbes can maintain both their structure and function.…

Soft Condensed Matter · Physics 2016-03-23 Q. Huang , K. N. Tran , J. M. Rodgers , D. H. Bartlett , R. J. Hemley , T. Ichiye

In order to gain a mechanistic understanding of how tinnitus emerges in the brain, we must build biologically plausible computational models that mimic both tinnitus development and perception, and test the tentative models with brain and…

Neurons and Cognition · Quantitative Biology 2020-10-06 Patrick Krauss , Achim Schilling

Unlike computation or the numerical analysis of differential equations, simulation does not have a well established conceptual and mathematical foundation. Simulation is an arguable unique union of modeling and computation. However,…

adap-org · Physics 2008-02-03 Steen Rasmussen , Christopher Barrett

Computation, the use of a computer to solve, simulate, or visualize a physical problem, has revolutionized how physics research is done. Computation is used widely to model systems, to simulate experiments, and to analyze data. Yet, in most…

Physics Education · Physics 2015-11-18 Marcos D. Caballero

Enhanced sampling algorithms have emerged as powerful methods to extend the utility of molecular dynamics simulations and allow the sampling of larger portions of the configuration space of complex systems in a given amount of simulation…

Statistical Mechanics · Physics 2022-12-19 Jérôme Hénin , Tony Lelièvre , Michael R. Shirts , Omar Valsson , Lucie Delemotte