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Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

Computation and Language · Computer Science 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

Machine Learning · Computer Science 2022-12-12 Harshit Parmar , Eric Walden

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

Computation and Language · Computer Science 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

It is acknowledged that the most common cause of dementia worldwide is Alzheimer's disease (AD). This condition progresses in severity from mild to severe and interferes with people's everyday routines. Early diagnosis plays a critical role…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Sajjad Aghasi Javid , Mahmood Mohassel Feghhi

Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…

Computation and Language · Computer Science 2023-07-18 M. Zakaria Kurdi

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Md Motiur Rahman Sagar , Martin Dyrba

Alzheimer's Disease (AD) is one of the most concerned neurodegenerative diseases. In the last decade, studies on AD diagnosis attached great significance to artificial intelligence (AI)-based diagnostic algorithms. Among the diverse…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Yechong Huang , Jiahang Xu , Yuncheng Zhou , Tong Tong , Xiahai Zhuang , the Alzheimer's Disease Neuroimaging Initiative

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Narotam Singh , Patteshwari. D , Neha Soni , Amita Kapoor