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We study the maximum likelihood model in emission tomography and propose a new family of algorithms for its solution, called String-Averaging Expectation-Maximization (SAEM). In the String-Averaging algorithmic regime, the index set of all…

Medical Physics · Physics 2019-04-03 E. S. Helou , Y. Censor , T. -B. Chen , I-L. Chern , Á. R. De Pierro , M. Jiang , H. H. -S. Lu

We present the first $\mathrm{o}(n)$-space polynomial-time algorithm for computing the length of a longest common subsequence. Given two strings of length $n$, the algorithm runs in $\mathrm{O}(n^{3})$ time with $\mathrm{O}\left(\frac{n…

Data Structures and Algorithms · Computer Science 2020-09-21 Masashi Kiyomi , Takashi Horiyama , Yota Otachi

The longest common substring problem consists in finding a longest string that appears as a (contiguous) substring of two input strings. We consider the dynamic variant of this problem, in which we are to maintain two dynamic strings $S$…

Data Structures and Algorithms · Computer Science 2026-04-09 Panagiotis Charalampopoulos , Paweł Gawrychowski , Karol Pokorski

Given a sequence of n numbers, the Maximum Consecutive Subsums Problem (MCSP) asks for the maximum consecutive sum of lengths l for each l = 1,...,n. No algorithm is known for this problem which is significantly better than the naive…

Data Structures and Algorithms · Computer Science 2015-09-21 Wilfredo Bardales Roncalla , Eduardo Laber , Ferdinando Cicalese

Variable Length Memory Chains (VLMC), which are generalizations of finite order Markov chains, turn out to be an essential tool to modelize random sequences in many domains, as well as an interesting object in contemporary probability…

Probability · Mathematics 2020-04-20 Peggy Cénac , Brigitte Chauvin , Camille Noûs , Frédéric Paccaut , Nicolas Pouyanne

The problem of identification of statistically significant patterns in a sequence of data has been applied to many domains such as intrusion detection systems, financial models, web-click records, automated monitoring systems, computational…

Databases · Computer Science 2012-07-03 Mayank Sachan , Arnab Bhattacharya

The Average Common Substring (ACS) is a popular alignment-free distance measure for phylogeny reconstruction. The ACS can be computed in O(n) space and time, where n=x+y is the input size. The compressed string matching is the study of…

Data Structures and Algorithms · Computer Science 2018-05-17 Sahar Hooshmand , Neda Tavakoli , Paniz Abedin , Sharma V. Thankachan

Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

Quantitative Methods · Quantitative Biology 2015-11-17 Kristóf Takács

Random linear codes (RLCs) are well known to have nice combinatorial properties and near-optimal parameters in many different settings. However, getting explicit constructions matching the parameters of RLCs is challenging, and RLCs are…

Information Theory · Computer Science 2023-08-31 Xue Chen , Kuan Cheng , Xin Li , Songtao Mao

This paper describes a linear-time algorithm that finds the longest stretch in a sequence of real numbers (``scores'') in which the sum exceeds an input parameter. The algorithm also solves the problem of finding the longest interval in…

Data Structures and Algorithms · Computer Science 2007-05-23 Miklós Csűrös

The distributions of the $m$-th longest runs of multivariate random sequences are considered. For random sequences made up of $k$ kinds of letters, the lengths of the runs are sorted in two ways to give two definitions of run length…

Combinatorics · Mathematics 2024-05-06 Yong Kong

The classic string indexing problem is to preprocess a string $S$ into a compact data structure that supports efficient subsequent pattern matching queries, that is, given a pattern string $P$, report all occurrences of $P$ within $S$. In…

Data Structures and Algorithms · Computer Science 2024-02-15 Philip Bille , Inge Li Gørtz , Max Rishøj Pedersen , Eva Rotenberg , Teresa Anna Steiner

Given two {0,1}-sequences X and Y of lengths m and n, respectively, we write L(X,Y) to denote the length of the longest common subsequence (LCS) of X and Y, and write L(m,n) to denote the expected value of L(X,Y) when X and Y are random…

Group Theory · Mathematics 2013-07-11 John D. Dixon

The Longest Common Increasing Subsequence (LCIS) is a variant of the classical Longest Common Subsequence (LCS), in which we additionally require the common subsequence to be strictly increasing. While the well-known "Four Russians"…

Data Structures and Algorithms · Computer Science 2020-03-31 Anadi Agrawal , Paweł Gawrychowski

We consider the problem of recovering a single or multiple frequency-sparse signals, which share the same frequency components, from a subset of regularly spaced samples. The problem is referred to as continuous compressed sensing (CCS) in…

Information Theory · Computer Science 2014-10-24 Zai Yang , Lihua Xie

Linear mixed models (LMMs), which incorporate fixed and random effects, are key tools for analyzing heterogeneous data, such as in personalized medicine. Nowadays, this type of data is increasingly wide, sometimes containing thousands of…

Machine Learning · Statistics 2026-05-15 Ryan Thompson , Matt P. Wand , Joanna J. J. Wang

In this paper we address the problem of discovering a small set of frequent serial episodes from sequential data so as to adequately characterize or summarize the data. We discuss an algorithm based on the Minimum Description Length (MDL)…

Machine Learning · Computer Science 2019-04-02 Soumyajit Mitra , P S Sastry

Several biological problems require the identification of regions in a sequence where some feature occurs within a target density range: examples including the location of GC-rich regions, identification of CpG islands, and sequence…

Data Structures and Algorithms · Computer Science 2013-08-15 Benjamin A. Burton , Mathias Hiron

The longest run subsequence (LRS) problem is an NP-hard combinatorial optimization problem belonging to the class of subsequence problems from bioinformatics. In particular, the problem plays a role in genome reassembly. In this paper, we…

Artificial Intelligence · Computer Science 2025-08-20 Christian Blum , Pedro Pinacho-Davidson

Algorithms to find optimal alignments among strings, or to find a parsimonious summary of a collection of strings, are well studied in a variety of contexts, addressing a wide range of interesting applications. In this paper, we consider…

Social and Information Networks · Computer Science 2020-11-09 Patty Commins , David Liben-Nowell , Tina Liu , Kiran Tomlinson