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Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Cryo-electron microscopy (cryo-EM) has become a major experimental technique to determine the structures of large protein complexes and molecular assemblies, as evidenced by the 2017 Nobel Prize. Although cryo-EM has been drastically…

Biomolecules · Quantitative Biology 2021-06-01 Dong Si , Andrew Nakamura , Runbang Tang , Haowen Guan , Jie Hou , Ammaar Firozi , Renzhi Cao , Kyle Hippe , Minglei Zhao

Atomistic simulations have become a powerful tool in materials research due to the extremely fine spatial and temporal resolution provided by such techniques. In order to understand the fundamental principles which govern material behavior…

Materials Science · Physics 2014-08-26 Jason F. Panzarino , Timothy J. Rupert

Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult especially for small particles with low contrast. As…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Ayelet Heimowitz , Joakim Andén , Amit Singer

We present an advanced scanning probe microscopy system enhanced with artificial intelligence (AI-SPM) designed for self-driving atomic-scale measurements. This system expertly identifies and manipulates atomic positions with high…

Computational Physics · Physics 2024-04-18 Zhuo Diao , Keiichi Ueda , Linfeng Hou , Fengxuan Li , Hayato Yamashita , Masayuki Abe

Microparticles ranging from sub-microns to millimeter in size are a common form of matter in magnetic fusion environment, and they are highly mobile due to their small mass. Different forces in addition to gravity can affect their motion…

Instrumentation and Detectors · Physics 2018-08-01 Pinghan Chu , Bradley T. Wolfe , Zhehui Wang

For over three decades, scanning probe microscopy (SPM) has been a key method for exploring material structures and functionalities at nanometer and often atomic scales in ambient, liquid, and vacuum environments. Historically, SPM…

A new experimental technique for investigating characteristics of plasma generated with plasmotrons in electrophysical installations was proposed. The technique involves a simultaneous registration of both radiation spectra and images of…

Plasma Physics · Physics 2007-05-23 V. Yu. Khomich , I. I. Kumkova , Yu. A. Zheleznov

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

The past decade has witnessed tremendous progress in the theoretical and computational tools that produce our understanding of nuclei. A number of microscopic calculations of nuclear electroweak structure and reactions have successfully…

Nuclear Theory · Physics 2018-03-14 Saori Pastore

The thermoelectric performance of materials exhibits complex nonlinear dependencies on both elemental types and their proportions, rendering traditional trial-and-error approaches inefficient and time-consuming for material discovery. In…

Materials Science · Physics 2025-04-14 Yuxuan Zeng , Wenhao Xie , Wei Cao , Tan Peng , Yue Hou , Ziyu Wang , Jing Shi

Laser cooled atoms are central to modern precision measurements. They are also increasingly important as an enabling technology for experimental cavity quantum electrodynamics, quantum information processing and matter wave interferometry.…

Precision spectroscopy has long played a central role in testing the foundations of physics, from the early insights that led to the development of quantum mechanics to the validation of quantum electrodynamics and the determination of…

High Energy Physics - Phenomenology · Physics 2026-02-26 Cédric Delaunay , Jean-Philippe Karr , Yotam Soreq

Power efficiency is becoming an ever more important metric for both high performance and high throughput computing. Over the course of next decade it is expected that flops/watt will be a major driver for the evolution of computer…

Computational Physics · Physics 2014-10-24 David Abdurachmanov , Peter Elmer , Giulio Eulisse , Shahzad Muzaffar

(Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of devices due to its time-intensive…

Quantum computers based on cold-atom arrays offer long-lived qubits with programmable connectivity, yet their progress toward fault-tolerant operation is limited by the relatively low fidelity of site-selective local control. We introduce…

Quantum Physics · Physics 2025-11-18 Sanghyo Park , Seuk Lee , Keunyoung Lee , Minhyeok Kim , Donggyu Kim

High precision atomic data is indispensable for experiments involving studies of fundamental interactions, astrophysics, atomic clocks, plasma science, and others. We develop new parallel atomic structure codes and explore the difficulties…

Atomic Physics · Physics 2021-03-11 C. Cheung , M. S. Safronova , S. G. Porsev

This primer is a brief introduction to the technologies used in particle detectors designed for high-energy particle physics experiments. The intended readers are students, especially undergraduates, starting laboratory work.

Instrumentation and Detectors · Physics 2019-06-13 A. A. Grillo

A method for the optimisation and advanced studies of a laser-plasma electron injector is presented, based on a truncated ionisation injection scheme for high quality beam production. The SMILEI code is used with laser envelope…

We propose a high-precision x-ray spectroscopy experiment of antiprotonic atoms to advance the understanding of low-energy antinucleon-nucleus interactions. The current leading model of antiproton-nucleus interactions is based on an optical…

Nuclear Experiment · Physics 2025-04-02 Takashi Higuchi , Hiroyuki Fujioka