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The ability to synthesize realistic patterns of neural activity is crucial for studying neural information processing. Here we used the Generative Adversarial Networks (GANs) framework to simulate the concerted activity of a population of…

Neurons and Cognition · Quantitative Biology 2018-04-18 Manuel Molano-Mazon , Arno Onken , Eugenio Piasini , Stefano Panzeri

Calcium imaging allows for the parallel measurement of large neuronal populations in a spatially resolved and minimally invasive manner, and has become a gold-standard for neuronal functionality. While deep generative models have been…

Neurons and Cognition · Quantitative Biology 2025-10-02 Berta Ros , Mireia Olives-Verger , Caterina Fuses , Josep M Canals , Jordi Soriano , Jordi Abante

Calcium imaging is an important technique for monitoring the activity of thousands of neurons simultaneously. As calcium imaging datasets grow in size, automated detection of individual neurons is becoming important. Here we apply a…

Neurons and Cognition · Quantitative Biology 2016-12-23 Noah J. Apthorpe , Alexander J. Riordan , Rob E. Aguilar , Jan Homann , Yi Gu , David W. Tank , H. Sebastian Seung

Understanding how activity in neural circuits reshapes following task learning could reveal fundamental mechanisms of learning. Thanks to the recent advances in neural imaging technologies, high-quality recordings can be obtained from…

Neurons and Cognition · Quantitative Biology 2021-11-29 Bryan M. Li , Theoklitos Amvrosiadis , Nathalie Rochefort , Arno Onken

Individual Neurons in the nervous systems exploit various dynamics. To capture these dynamics for single neurons, we tune the parameters of an electrophysiological model of nerve cells, to fit experimental data obtained by calcium imaging.…

Quantitative Methods · Quantitative Biology 2017-11-07 Magdalena Fuchs , Manuel Zimmer , Radu Grosu , Ramin M. Hasani

Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis. However, for functional calcium traces, existing approaches remain task-specific, limiting transfer across common neuroscience…

Quantitative Methods · Quantitative Biology 2026-04-09 Xinhong Xu , Yimeng Zhang , Qichen Qian , Yuanlong Zhang

Access to medical data is highly restricted due to its sensitive nature, preventing communities from using this data for research or clinical training. Common methods of de-identification implemented to enable the sharing of data are…

Signal Processing · Electrical Eng. & Systems 2019-09-23 Anne Marie Delaney , Eoin Brophy , Tomas E. Ward

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

Generative Adversarial Networks (GAN) are known to produce synthetic data that are difficult to discern from real ones by humans. In this paper we present an approach to use GAN to produce realistically looking ECG signals. We utilize them…

Machine Learning · Computer Science 2020-09-08 Karol Antczak

In medical imaging, a general problem is that it is costly and time consuming to collect high quality data from healthy and diseased subjects. Generative adversarial networks (GANs) is a deep learning method that has been developed for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Per Welander , Simon Karlsson , Anders Eklund

Generative Adversarial Networks (GANs) have been used widely to generate large volumes of synthetic data. This data is being utilized for augmenting with real examples in order to train deep Convolutional Neural Networks (CNNs). Studies…

Computer Vision and Pattern Recognition · Computer Science 2020-06-18 Binod Bhattarai , Seungryul Baek , Rumeysa Bodur , Tae-Kyun Kim

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Amirata Ghorbani , Vivek Natarajan , David Coz , Yuan Liu

In this research, we introduce an innovative method for synthesizing medical images using generative adversarial networks (GANs). Our proposed GANs method demonstrates the capability to produce realistic synthetic images even when trained…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yinqiu Feng , Bo Zhang , Lingxi Xiao , Yutian Yang , Tana Gegen , Zexi Chen

Remarkable progress has been achieved in synthesizing photo-realistic images with generative adversarial networks (GANs). Recently, GANs are utilized as the training sample generator when obtaining or storing real training data is expensive…

Machine Learning · Computer Science 2022-12-22 Bo Zhao , Hakan Bilen

Automatic analysis of spatio-temporal microscopy images is inevitable for state-of-the-art research in the life sciences. Recent developments in deep learning provide powerful tools for automatic analyses of such image data, but heavily…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Dennis Bähr , Dennis Eschweiler , Anuk Bhattacharyya , Daniel Moreno-Andrés , Wolfram Antonin , Johannes Stegmaier

Electrocardiogram (ECG) data collection during emergency situations is challenging, making ECG data generation an efficient solution for dealing with highly imbalanced ECG training datasets. In this paper, we propose a novel approach for…

Signal Processing · Electrical Eng. & Systems 2023-06-06 Nour Neifar , Achraf Ben-Hamadou , Afef Mdhaffar , Mohamed Jmaiel , Bernd Freisleben

One of the biggest issues facing the use of machine learning in medical imaging is the lack of availability of large, labelled datasets. The annotation of medical images is not only expensive and time consuming but also highly dependent on…

Generative Adversarial Networks (GANs) have shown remarkable success as a framework for training models to produce realistic-looking data. In this work, we propose a Recurrent GAN (RGAN) and Recurrent Conditional GAN (RCGAN) to produce…

Machine Learning · Statistics 2017-12-05 Cristóbal Esteban , Stephanie L. Hyland , Gunnar Rätsch

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

In the recent years Generative Adversarial Networks (GANs) have demonstrated significant progress in generating authentic looking data. In this work we introduce our simple method to exploit the advancements in well established image-based…

Machine Learning · Computer Science 2019-10-31 Eoin Brophy , Zhengwei Wang , Tomas E. Ward
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