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We present a generalized theoretical framework for olfactory representation and plasticity, using the theory of smooth manifolds and sheaves to depict categorical odor learning via distributed neural computation. Beginning with the space of…

Neurons and Cognition · Quantitative Biology 2023-10-13 Jack A. Cook , Thomas A. Cleland

Olfaction, the sense of smell, has received scant attention from a signal processing perspective in comparison to audition and vision. In this paper, we develop a signal processing paradigm for olfactory signals based on new scientific…

Information Theory · Computer Science 2015-09-16 Kush R. Varshney , Lav R. Varshney

This article provides a background and descriptive analysis of insect memory and the coding of olfactory sensation in Drosophila, presenting graphs and summary statistics from a large dataset of neurons and synapses that was recently made…

Neurons and Cognition · Quantitative Biology 2022-09-07 Chris Rohlfs

During the past few years the development of experimental techniques has allowed the quantitative analysis of biological systems ranging from neurobiology and molecular biology. This work focuses on the quantitative description of these…

Biomolecules · Quantitative Biology 2011-09-19 Carlo Barbieri

In this study, we explore how the combination of synthetic biology, neuroscience modeling, and neuromorphic electronic systems offers a new approach to creating an artificial system that mimics the natural sense of smell. We argue that a…

Neural and Evolutionary Computing · Computer Science 2025-08-04 Kevin Max , Larissa Sames , Shimeng Ye , Jan Steinkühler , Federico Corradi

We present a model of an olfactory system that performs odor segmentation. Based on the anatomy and physiology of natural olfactory systems, it consists of a pair of coupled modules, bulb and cortex. The bulb encodes the odor inputs as…

Disordered Systems and Neural Networks · Physics 2007-05-23 Zhaoping Li , John Hertz

Olfaction -- how molecules are perceived as odors to humans -- remains poorly understood. Recently, the principal odor map (POM) was introduced to digitize the olfactory properties of single compounds. However, smells in real life are not…

Machine Learning · Computer Science 2025-01-28 Gary Tom , Cher Tian Ser , Ella M. Rajaonson , Stanley Lo , Hyun Suk Park , Brian K. Lee , Benjamin Sanchez-Lengeling

Advances in neural sensing technology are making it possible to observe the olfactory process in great detail. In this paper, we conceptualize smell from a Data Science and AI perspective, that relates the properties of odorants to how they…

Neurons and Cognition · Quantitative Biology 2024-04-09 Vivek Agarwal , Joshua Harvey , Dmitry Rinberg , Vasant Dhar

Olfaction lies at the intersection of chemical structure, neural encoding, and linguistic perception, yet existing representation methods fail to fully capture this pathway. Current approaches typically model only isolated segments of the…

Computation and Language · Computer Science 2026-04-21 Yanyi Su , Hongshuai Wang , Zhifeng Gao , Jun Cheng

Hopfield models, originally developed to study memory retrieval in neural networks, have become versatile tools for modeling diverse biological systems in which function emerges from collective dynamics. In this review, we provide a…

Biological Physics · Physics 2025-06-17 Maria Yampolskaya , Pankaj Mehta

Storing memory for molecular recognition is an efficient strategy for responding to external stimuli. Biological processes use different strategies to store memory. In the olfactory cortex, synaptic connections form when stimulated by an…

Biological Physics · Physics 2021-06-07 Oskar H Schnaack , Luca Peliti , Armita Nourmohammad

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

Physics and Society · Physics 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

We address the problem of building theoretical models that help elucidate the function of the visual brain at computational/algorithmic and structural/mechanistic levels. We seek to understand how the receptive fields and topographic maps…

Neural and Evolutionary Computing · Computer Science 2020-11-10 Simon Osindero

Deep learning is transforming many areas in science, and it has great potential in modeling molecular systems. However, unlike the mature deployment of deep learning in computer vision and natural language processing, its development in…

Computational Physics · Physics 2021-03-19 Jun Zhang , Yao-Kun Lei , Zhen Zhang , Junhan Chang , Maodong Li , Xu Han , Lijiang Yang , Yi Isaac Yang , Yi Qin Gao

We explore end-to-end trained differentiable models that integrate natural logic with neural networks, aiming to keep the backbone of natural language reasoning based on the natural logic formalism while introducing subsymbolic vector…

Computation and Language · Computer Science 2020-11-11 Yufei Feng , Zi'ou Zheng , Quan Liu , Michael Greenspan , Xiaodan Zhu

We introduce and study an artificial neural network, inspired by the probabilistic Receptor Affinity Distribution model of olfaction. Our system consists on N sensory neurons whose outputs converge on a single processing linear threshold…

Disordered Systems and Neural Networks · Physics 2007-05-23 N. Caticha , J. E. Palo Tejada , D. Lancet , E. Domany

Understanding how molecular structure gives rise to odor perception remains a long-standing challenge, with ongoing debate over whether olfaction is primarily governed by molecular shape, vibrational properties, or their interplay at the…

Materials Science · Physics 2026-04-14 P. Zanineli , E. V. C. Lopes , G. R. Schleder , L. N. Lemos , F. Crasto de Lima , A. Fazzio

Integration between biology and information science benefits both fields. Many related models have been proposed, such as computational visual cognition models, computational motor control models, integrations of both and so on. In general,…

Computer Vision and Pattern Recognition · Computer Science 2016-03-28 Peijie Yin , Hong Qiao , Wei Wu , Lu Qi , YinLin Li , Shanlin Zhong , Bo Zhang

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar

The mathematical representation of semantics is a key issue for Natural Language Processing (NLP). A lot of research has been devoted to finding ways of representing the semantics of individual words in vector spaces. Distributional…

Computation and Language · Computer Science 2014-11-13 Karl Moritz Hermann
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