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A modified weak measurement scheme, rotatory biased weak measurement, is proposed to significantly improve the sensitivity and resolution of the refractive index sensor on a total reflection structure. This method introduces an additional…

Quantum Physics · Physics 2022-04-25 Chongqi Zhou , Yang Xu , Xiaonan Zhang , Zhangyan Li , Tian Guan , Yonghong He , Yanhong Ji

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

Refractive index of tubulin is an important parameter underlying fundamental electromagnetic and biophysical properties of microtubules - protein fibers essential for several cell functions including cell division. Yet, the only…

Biological Physics · Physics 2017-04-05 Ondrej Krivosudský , Pavel Dráber , Michal Cifra

A method is presented to infer simultaneously the wavelength-dependent real refractive index (RI) of the material of microspheres and their size distribution from extinction measurements of particle suspensions. To derive the averaged…

Optics · Physics 2018-05-23 Jonas Gienger , Markus Bär , Jörg Neukammer

We present our results for simultaneous measurement of the refractive indices of gallium arsenide (GaAs) and aluminum gallium arsenide (Al$_\mathrm{x}$Ga$_\mathrm{1-x}$As) from $2.0$ to $7.1\,\mathrm{\mu m}$ ($5000$ to…

Holotomography, a three-dimensional quantitative phase imaging technique, presents an innovative, non-invasive approach to studying biological samples by exploiting the refractive index as an intrinsic imaging contrast. Despite offering…

Optics · Physics 2023-08-04 Herve Hugonnet , HyunJun Han , Weisun Park , YongKeun Park

Vibrational spectroscopy, comprised of infrared absorption and Raman scattering spectroscopy, is widely used for label-free optical sensing and imaging in various scientific and industrial fields. The group theory states that the two…

Chemical Physics · Physics 2019-10-09 Kazuki Hashimoto , Venkata Ramaiah Badarla , Akira Kawai , Takuro Ideguchi

Non-contact measurement of the refractive index and thickness of multilayer biological tissues is of great significance for biomedical applications and can greatly improve medical diagnosis and treatment. In this work, we introduce a…

Optics · Physics 2024-04-19 Yu-Lin Ku , Yao-Gen Shu

Total internal reflection fluorescence (TIRF) microscopy and its variants are key technologies for visualizing the dynamics of single molecules or organelles in live cells. Yet, truely quantitative TIRF remains problematic. One unknown…

Biological Physics · Physics 2017-06-07 Maia Brunstein , Lopamudra Roy , Martin Oheim

We present a technique for extracting Raman intensities from ab initio molecular dynamics (MD) simulations at high temperature. The method is applied to the highly anharmonic case of dense hydrogen up to 500 K for pressures ranging from 180…

Materials Science · Physics 2013-02-25 Ioan B. Magdau , Graeme J. Ackland

In this work, we propose a novel method for continuous real-time measurement of the dynamics of the nonlinear refractive index n2. This is particularly important for characterizing phenomena or materials (such as biological tissues, gases…

Raman spectroscopy is a widely-used non-destructive material characterization method, which provides information about the vibrational modes of the material and therefore of its atomic structure and chemical composition. Interpretation of…

Computational Physics · Physics 2023-02-09 Mohammad Bagheri , Hannu-Pekka Komsa

This paper proposes a new X-ray radiographic technique for measuring density uniformity of silica aerogels used as radiator in proximity-focusing ring-imaging Cherenkov detectors. To obtain high performance in a large-area detector, a key…

Instrumentation and Detectors · Physics 2012-12-17 Makoto Tabata , Yoshikiyo Hatakeyama , Ichiro Adachi , Takeshi Morita , Keiko Nishikawa

We introduce a machine learning prediction workflow to study the impact of defects on the Raman response of 2D materials. By combining the use of machine-learned interatomic potentials, the Raman-active $\Gamma$-weighted density of states…

Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

We demonstrate low-frequency interferometric impulsive stimulated Raman scattering (ISRS) imaging with high robustness to distortions by optical scattering. ISRS is a pump-probe coherent Raman spectroscopy that can capture Raman vibrational…

We report a proof-of-principle experiment where the refractive index of an atomic vapor is enhanced while maintaining vanishing absorption of the beam. The key idea is to drive alkali atoms in a vapor with appropriate control lasers and…

Quantum Physics · Physics 2009-01-09 N. A. Proite , B. E. Unks , J. T. Green , D. D. Yavuz

Refractive index sensing is a highly sensitive and label-free detection method for molecular binding events. Commercial implementations of biosensing concepts based on plasmon resonances typically require significant external…

Instrumentation and Detectors · Physics 2019-02-05 Lion Augel , Yuma Kawaguchi , Stefan Bechler , Roman Körner , Jörg Schulze , Hironaga Uchida , Inga A. Fischer

Large liquid argon detectors have become widely used in low rate experiments, including dark matter and neutrino research. However, the optical properties of liquid argon are not well understood at the large scales relevant for current and…

Instrumentation and Detectors · Physics 2017-08-15 Emily Grace , Alistair Butcher , Jocelyn Monroe , James A. Nikkel

We measured polarized far-infrared reflectivity and Raman scattering spectra of SrCuO$_2$ single crystals. The frequencies for infrared-active modes were determined using an oscillator-fitting procedure of reflectivity data. The Raman…

Strongly Correlated Electrons · Physics 2009-10-31 Z. V. Popović , M. J. Konstantinović , R. Gajić , C. Thomsen , U. Kuhlmann , A. Vietkin
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