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A widely tested approach to overcoming the diffraction limit in microscopy without disturbing the sample relies on substituting widefield sample illumination with a structured light beam. This gives rise to confocal, image-scanning and…

Optics · Physics 2024-06-03 Alexander Duplinskiy , Jernej Frank , Kaden Bearne , A. I. Lvovsky

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Despite advances in deep learning, robustness under domain shift remains a major bottleneck in medical imaging settings. Findings on natural images suggest that deep neural models can show a strong textural bias when carrying out image…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Seoin Chai , Daniel Rueckert , Ahmed E. Fetit

Image simulation remains under-exploited for the most widely used biological phase microscopy methods, because of difficulties in simulating partially coherent illumination. We describe an open-source toolbox, microlith…

Optics · Physics 2014-05-14 Shalin B. Mehta , Rudolf Oldenbourg

It is now generally accepted that Euclidean-based metrics may not always adequately represent the subjective judgement of a human observer. As a result, many image processing methodologies have been recently extended to take advantage of…

Optimization and Control · Mathematics 2020-02-10 D. Otero , D. La Torre , O. Michailovich , E. R. Vrscay

Microscopy enables direct observation of cellular morphology in 3D, with transmitted-light methods offering low-cost, minimally invasive imaging and fluorescence microscopy providing specificity and contrast. Virtual staining combines these…

Objective: To improve accelerated MRI reconstruction through a densely connected cascading deep learning reconstruction framework. Materials and Methods: A cascading deep learning reconstruction framework (baseline model) was modified by…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Jon Andre Ottesen , Matthan W. A. Caan , Inge Rasmus Groote , Atle Bjørnerud

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

Applied Physics · Physics 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

This work investigates the production of high-resolution images of typical support elements in concrete structures by means of muon tomography (muography). By exploiting detailed Monte Carlo radiation-matter simulations, we demonstrate the…

Stacked intelligent metasurfaces (SIM) represents an advanced signal processing paradigm that enables over-the-air processing of electromagnetic waves at the speed of light. Its multi-layer structure exhibits customizable increased…

Signal Processing · Electrical Eng. & Systems 2024-02-15 Hao Liu , Jiancheng An , Derrick Wing Kwan Ng , George C. Alexandropoulos , Lu Gan

Stacked intelligent metasurfaces (SIMs) represent a novel signal processing paradigm that enables over-the-air processing of electromagnetic waves at the speed of light. Their multi-layer architecture exhibits customizable computational…

Information Theory · Computer Science 2025-04-01 Hao Liu , Jiancheng An , George C. Alexandropoulos , Derrick Wing Kwan Ng , Chau Yuen , Lu Gan

High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D…

Image and Video Processing · Electrical Eng. & Systems 2024-03-20 Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Juan Eugenio Iglesias

Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Hyoungjun Park , Myeongsu Na , Bumju Kim , Soohyun Park , Ki Hean Kim , Sunghoe Chang , Jong Chul Ye

This retrospective-prospective study evaluated whether a deep learning-based MRI reconstruction algorithm can preserve diagnostic quality in brain MRI scans accelerated up to fourfold, using both public and prospective clinical data. The…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Jonathan I. Mandel , Shivaprakash Hiremath , Hedyeh Keshtgar , Timothy Scholl , Sadegh Raeisi

Deep learning methods have been successfully applied to various computer vision tasks. However, existing neural network architectures do not per se incorporate domain knowledge about the addressed problem, thus, understanding what the model…

Computer Vision and Pattern Recognition · Computer Science 2019-10-21 Iman Marivani , Evaggelia Tsiligianni , Bruno Cornelis , Nikos Deligiannis

Magnetic Resonance Imaging (MRI) is a powerful imaging technique widely used for visualizing structures within the human body and in other fields such as plant sciences. However, there is a demand to develop fast 3D-MRI reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Arya Bangun , Zhuo Cao , Alessio Quercia , Hanno Scharr , Elisabeth Pfaehler

X-ray imaging is the most widely used medical imaging modality. However, in the common practice, inconsistency in the initial presentation of X-ray images is a common complaint by radiologists. Different patient positions, patient habitus…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Hongxu Yang , Najib Akram Aboobacker , Xiaomeng Dong , German Gonzalez , Lehel Ferenczi , Gopal Avinash

The iterative refinement method (IRM) has been very successfully applied in many different fields for examples the modern quantum chemical calculation and CT image reconstruction. It is proved that the refinement method can create an exact…

Medical Physics · Physics 2015-12-23 Kang Yang , Kevin Yang , Xintie Yang , Shuang-Ren Zhao

The use of the structural similarity index (SSIM) is widespread. For almost two decades, it has played a major role in image quality assessment in many different research disciplines. Clearly, its merits are indisputable in the research…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Jim Nilsson , Tomas Akenine-Möller
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