Related papers: Computed extended depth of field optical-resolutio…
We report an inverse-designed, high numerical aperture (~0.44), extended depth of focus (EDOF) meta-optic, which exhibit a lens-like point spread function (PSF). The EDOF meta-optic maintains a focusing efficiency comparable to that of a…
Quantitative photoacoustic tomography is an emerging imaging technique aimed at estimating the distribution of optical parameters inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic…
In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…
Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…
Recent advances in deep learning for tomographic reconstructions have shown great potential to create accurate and high quality images with a considerable speed-up. In this work we present a deep neural network that is specifically designed…
Photoacoustic (PA) computed tomography (PACT) reconstructs the initial pressure distribution from raw PA signals. The standard reconstruction of medical image could cause the artifacts due to interferences or ill-posed setup. Recently, deep…
Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…
Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…
In recent years, photoacoustics has attracted intensive research for both anatomical and functional biomedical imaging. However, the physical interaction between photoacoustic generated endogenous waves and an exogenous ultrasound wave is a…
Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…
Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…
Power Doppler ultrasound is in widespread clinical use for non-invasive vascular imaging but the most common current method - Delay and Sum (DAS) beamforming - suffers from limited resolution and high side-lobes. Here we propose the…
Optical coherence tomography (OCT) has proven to be a powerful technique for studying tissue morphology in ophthalmology, cardiology, and endomicroscopy. Its performance is limited by the fundamental trade-off between the imaging…
Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…
High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…
Recent advances in photoacoustic (PA) imaging have enabled detailed images of microvascular structure and quantitative measurement of blood oxygenation or perfusion. Standard reconstruction methods for PA imaging are based on solving an…
Photoacoustic tomography seeks to reconstruct an acoustic initial pressure distribution from the measurement of the ultrasound waveforms. Conventional methods assume a-prior knowledge of the sound speed distribution, which practically is…
As demand for advanced photographic applications on hand-held devices grows, these electronics require the capture of high quality depth. However, under low-light conditions, most devices still suffer from low imaging quality and inaccurate…
Photoacoustic computed tomography (PACT) is a hybrid imaging modality, which combines the high optical contrast of pure optical imaging and the high penetration depth of ultrasound imaging. However, photoacoustic image dataset with good…
Volumetric biological imaging often involves compromising high temporal resolution at the expense of high spatial resolution when popular scanning methods are used to capture 3D information. We introduce an integrated experimental and image…