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Photoacoustic tomography (PAT) is a nonionizing imaging modality capable of acquiring high contrast and resolution images of optical absorption at depths greater than traditional optical imaging techniques. Practical considerations with…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Steven Guan , Amir A. Khan , Siddhartha Sikdar , Parag V. Chitnis

Acoustic-resolution optoacoustic microscopy (AR-OAM) retrieves anatomical and functional contrast from living tissues at depths not reachable with optical microscopy. The imaging performance of AR-OAM has been advanced with image…

Photo-acoustic spectroscopy (PAS) is one of the most sensitive non-destructive analysis techniques for gases, fluids and solids. It can operate background-free at any wavelength and is applicable to microscopic and even non-transparent…

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

Medical Physics · Physics 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

Photoacoustic imaging (PAI) is an emerging biomedical imaging modality capable of providing both high contrast and high resolution of optical and UltraSound (US) imaging. When a short duration laser pulse illuminates the tissue as a target…

Signal Processing · Electrical Eng. & Systems 2018-01-19 Moein Mozaffarzadeh , Ali Mahloojifar , Mahdi Orooji

Fiber-form optics extends the high-resolution tomographic imaging capabilities of Optical Coherence Tomography (OCT) to the inside of the human body, i.e., endoscopic OCT. However, it still faces challenges due to the trade-off between…

Optics · Physics 2024-09-04 Chengfu Gu , Haoran Zhang , Qi Lan , Weiyi Zhang , Chang Liu , Jianlong Yang

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that…

Medical Physics · Physics 2016-11-17 Kun Wang , Robert W Schoonover , Richard Su , Alexander Oraevsky , Mark A Anastasio

The freedom of design of coded masks used by mask-based lensless cameras is an advantage these systems have when compared to lens-based ones. We leverage this freedom of design to propose a shape-preserving optimization scheme for a…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Jose Reinaldo Cunha Santos A V Silva Neto , Tomoya Nakamura , Yasushi Makihara , Yasushi Yagi

We developed a Bessel-beam photoacoustic microscopical simulation platform by using the k-Wave: MATLAB toolbox. The simulation platform uses the ring slit method to generate Bessel beam. By controlling the inner and outer radius of the ring…

Medical Physics · Physics 2020-09-23 Xianlin Song , Jianshuang Wei , Lingfang Song

We present a virtual image refocusing method over an extended depth of field (DOF) enabled by cascaded neural networks and a double-helix point-spread function (DH-PSF). This network model, referred to as W-Net, is composed of two cascaded…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Xilin Yang , Luzhe Huang , Yilin Luo , Yichen Wu , Hongda Wang , Yair Rivenson , Aydogan Ozcan

We present a proof-of-concept end-to-end system for computational extended depth of field (EDOF) imaging. The acquisition is performed through a phase-coded aperture implemented by placing a thin wavelength-dependent optical mask inside the…

Computer Vision and Pattern Recognition · Computer Science 2016-08-04 Tal Remez , Or Litany , Shachar Yoseff , Harel Haim , Alex Bronstein

Light microscopy enables multifunctional imaging of biological specimens at unprecedented depths and resolutions. However, the performance of all optical methods degrades with the imaging depth due to sample-induced aberrations. Methods of…

Optics · Physics 2019-02-06 Lyubov V. Amitonova

Optical imaging systems are generally limited by the depth of field because of the nature of the optics. Therefore, extending depth of field (EDoF) is a fundamental task for meeting the requirements of emerging visual applications. To solve…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Zhilong Li , Kejun Wu , Qiong Liu , You Yang

In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Recent advances in propagation-based phase-contrast imaging, such as hierarchical imaging, have enabled the visualization of internal structures in large biological specimens and material samples. However, modulation-based techniques, which…

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

Computational techniques have gained significant traction in photonics, enabling the co-design of hardware and data processing algorithms to drastically simplify optical system architectures and improve their performance. However, their…

Optics · Physics 2026-01-19 J. J. Navarro-Alventosa , A. Aupart-Acosta , V. Duran

Multimode fibres are becoming increasingly attractive in optical endoscopy as they promise to enable unparalleled miniaturisation, spatial resolution and cost as compared to conventional fibre bundle-based counterpart. However, achieving…

Medical Physics · Physics 2024-06-05 Tianrui Zhao , Michelle T. Ma , Sebastien Ourselin , Tom Vercauteren , Wenfeng Xia

Photon pair entangled in high dimensional orbital angular momentum (OAM) degree of freedom (DOF) has been widely regarded as a possible source in improving the capacity of quantum information processing. The need for the generation of a…

Quantum Physics · Physics 2020-05-20 Shilong Liu , Yingwen Zhang , Chen Yang , Shikai Liu , Zheng Ge , Yinhai Li , Yan Li , Zhiyuan Zhou , Guangcan Guo , Baosen Shi

Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…

Computational Physics · Physics 2019-12-23 Hwan Goh , Timo Lahivaara , Tanja Tarvainen , Aki Pulkkinen , Owen Dillon , Ruanui Nicholson , Jari Kaipio