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Recently the materials possessing structure of molecular and supramolecular matrix are more and more actively studied. They are relative to many polymeric materials of a technological origin, such as rubber, and living biological tissues.…

Adaptation and Self-Organizing Systems · Physics 2013-06-27 A. A. Bedulina , A. V. Kobelev

It is stated in the main in essence new approach to mechanics of the stressed state of the solid body from statistically isotropic material and the homogeneous liquid dynamics. The approach essence is in the detected property of the…

Fluid Dynamics · Physics 2008-09-25 S. L. Arsenjev

A novel data-driven constitutive modeling approach is proposed, which combines the physics-informed nature of modeling based on continuum thermodynamics with the benefits of machine learning. This approach is demonstrated on…

Computational Engineering, Finance, and Science · Computer Science 2023-04-28 Kshitiz Upadhyay , Jan N. Fuhg , Nikolaos Bouklas , K. T. Ramesh

Model-free data-driven computational mechanics replaces phenomenological constitutive functions by numerical simulations based on data sets of representative samples in stress-strain space. The distance of strain and stress pairs from the…

Computational Engineering, Finance, and Science · Computer Science 2021-11-29 Kerem Ciftci , Klaus Hackl

The study is devoted to the geometrically nonlinear simulation of fiber-reinforced composite structures. The applicability of the multiplicative approach to the simulation of viscoelastic properties of a composite material is assessed,…

Applied Physics · Physics 2021-03-15 I. I. Tagiltsev , P. P. Laktionov , A. V. Shutov

Soft biological tissues exhibit a tendency to maintain a preferred state of tensile stress, known as tensional homeostasis, which is restored even after external mechanical stimuli. This macroscopic behavior can be described using the…

Machine Learning · Computer Science 2025-01-23 Hagen Holthusen , Tim Brepols , Kevin Linka , Ellen Kuhl

As the cover of embryos and adult organisms, epithelial tissues are subjected to substantial mechanical forces in tissue morphogenesis. However, the finite deformation behaviors of epithelial tissues remain largely unexplored. This study…

Biological Physics · Physics 2025-12-29 Yuan He , Shi-Lei Xue

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

Crystal plasticity theory is often employed to predict the mesoscopic states of polycrystalline metals, and is well-known to be costly to simulate. Using a neural network with convolutional layers encoding correlations in time and space, we…

Computational Physics · Physics 2019-10-09 Ari Frankel , Kousuke Tachida , Reese Jones

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

The incremental stress-strain relation of dense packings of polygons is investigated here by using molecular dynamics simulations. The comparison of the simulation results to the continuous theories is performed using explicit expressions…

Materials Science · Physics 2016-08-16 F. Alonso-Marroquín , H. J. Herrmann

The two-phase composite approach of Estrin et al. (1998) describes an evolving dislocation cell structure. Mckenzie et al. (2007) enhanced the model to capture the effects of hydrostatic pressure and temperature during severe plastic…

Materials Science · Physics 2013-03-08 C. B. Silbermann , A. V. Shutov , J. Ihlemann

Recently, much attention has been given to a noteworthy property of some soft tissues: their ability to grow. Many attempts have been made to model this behaviour in biology, chemistry and physics. Using the theory of finite elasticity,…

Tissues and Organs · Quantitative Biology 2009-11-13 Julien Dervaux , Martine Ben Amar

The development of complex multicellular organisms from a single parent cell is a highly orchestrated process that cells conduct collectively without central guidance, creating intricate dynamic patterns essential for development and…

Soft Condensed Matter · Physics 2025-05-29 Siavash Monfared , Aleksandra Ardaševa , Amin Doostmohammadi

Plant organ outgrowth superficially appears like the continuous mechanical deformation of a sheet of cells. Yet, how precisely cells as individual mechanical entities can act to morph a tissue reliably and efficiently into three dimensions…

Biological Physics · Physics 2020-04-28 Jason Khadka , Jean-Daniel Julien , Karen Alim

Tissue deformations during morphogenesis can be active, driven by internal processes, or passive, resulting from stresses applied at their boundaries. Here, we introduce the Drosophila hindgut primordium as a model for studying…

During embryonic development tissue morphogenesis and signaling are tightly coupled. It is therefore important to simulate both tissue morphogenesis and signaling simultaneously in in silico models of developmental processes. The resolution…

Tissues and Organs · Quantitative Biology 2013-05-28 Dagmar Iber , Simon Tanaka , Patrick Fried , Philipp Germann , Denis Menshykau

This article deals with a viscoplastic material model of overstress type. The model is based on a multiplicative decomposition of the deformation gradient into elastic and inelastic part. An additional multiplicative decomposition of…

Numerical Analysis · Mathematics 2015-05-13 A. V. Shutov , R. Kreissig

Recoverable strain is the strain recovered once a stress is removed from a body, in the direction opposite to that in which the stress had acted. To date, the phenomenon has been understood as being elastic in origin: polymer chains…

Soft Condensed Matter · Physics 2025-05-07 Henry A. Lockwood , Suzanne M. Fielding

Generative modeling of anatomical structures plays a crucial role in virtual imaging trials, which allow researchers to perform studies without the costs and constraints inherent to in vivo and phantom studies. For clinical relevance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Bram de Wilde , Max T. Rietberg , Guillaume Lajoinie , Jelmer M. Wolterink
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