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Purpose: Recently, there has been a revived interest in system neuroscience causation models, driven by their unique capability to unravel complex relationships in multi-scale brain networks. In this paper, we present a novel method that…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Dachuan Song , Li Shen , Duy Duong-Tran , Xuan Wang

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Brain decoding is a field of computational neuroscience that uses measurable brain activity to infer mental states or internal representations of perceptual inputs. Therefore, we propose a novel approach to brain decoding that also relies…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Matteo Ferrante , Tommaso Boccato , Nicola Toschi

Existing research on making sense of deep neural networks often focuses on neuron-level interpretation, which may not adequately capture the bigger picture of how concepts are collectively encoded by multiple neurons. We present…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Haekyu Park , Nilaksh Das , Rahul Duggal , Austin P. Wright , Omar Shaikh , Fred Hohman , Duen Horng Chau

Brain metabolism is controlled by complex regulation mechanisms. As part of their nature many complex systems show scaling behavior in their timeseries data. Corresponding scaling exponents can sometimes be used to characterize these…

Condensed Matter · Physics 2007-05-23 Stefan Thurner , Christian Windischberger , Ewald Moser , Markus Barth

In recent years, functional magnetic resonance imaging has emerged as a powerful tool for investigating the human brain's functional connectivity networks. Related studies demonstrate that functional connectivity networks in the human brain…

Artificial Intelligence · Computer Science 2023-09-18 Xiangzhu Meng , Wei Wei , Qiang Liu , Shu Wu , Liang Wang

Multi-regional interaction among neuronal populations underlies the brain's processing of rich sensory information in our daily lives. Recent neuroscience and neuroimaging studies have increasingly used naturalistic stimuli and experimental…

Neurons and Cognition · Quantitative Biology 2021-06-08 Yu Takagi , Laurence T. Hunt , Ryu Ohata , Hiroshi Imamizu , Jun-ichiro Hirayama

Accurate brain parcellation in diffusion MRI (dMRI) space is essential for advanced neuroimaging analyses. However, most existing approaches rely on anatomical MRI for segmentation and inter-modality registration, a process that can…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Yousef Sadegheih , Dorit Merhof

Cluster inference based on spatial extent thresholding is the most popular analysis method for finding activated brain areas in neuroimaging. However, the method has several well-known issues. While powerful for finding brain regions with…

Methodology · Statistics 2022-08-10 Jelle J. Goeman , Paweł\ Górecki , Ramin Monajemi , Xu Chen , Thomas E. Nichols , Wouter Weeda

Concept-selective regions within the human cerebral cortex exhibit significant activation in response to specific visual stimuli associated with particular concepts. Precisely localizing these regions stands as a crucial long-term goal in…

Neurons and Cognition · Quantitative Biology 2025-03-05 Guangyin Bao , Qi Zhang , Zixuan Gong , Zhuojia Wu , Duoqian Miao

Traditional psychological experiments utilizing naturalistic stimuli face challenges in manual annotation and ecological validity. To address this, we introduce a novel paradigm leveraging multimodal large language models (LLMs) as proxies…

Artificial Intelligence · Computer Science 2025-02-27 Xin Liu , Ziyue Zhang , Jingxin Nie

We present two related methods for deriving connectivity-based brain atlases from individual connectomes. The proposed methods exploit a previously proposed dense connectivity representation, termed continuous connectivity, by first…

Neurons and Cognition · Quantitative Biology 2018-08-14 Anvar Kurmukov , Ayagoz Mussabayeva , Yulia Denisova , Daniel Moyer , Boris Gutman

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

We introduce BrainSAIL, a method for linking neural selectivity with spatially distributed semantic visual concepts in natural scenes. BrainSAIL leverages recent advances in large-scale artificial neural networks, using them to provide…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Andrew F. Luo , Jacob Yeung , Rushikesh Zawar , Shaurya Dewan , Margaret M. Henderson , Leila Wehbe , Michael J. Tarr

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Medical image segmentation, the task of partitioning an image into meaningful parts, is an important step toward automating medical image analysis and is at the crux of a variety of medical imaging applications, such as computer aided…

Computer Vision and Pattern Recognition · Computer Science 2016-07-06 Masoud S. Nosrati , Ghassan Hamarneh

Cognitive brain imaging is accumulating datasets about the neural substrate of many different mental processes. Yet, most studies are based on few subjects and have low statistical power. Analyzing data across studies could bring more…

Machine Learning · Statistics 2021-05-20 Arthur Mensch , Julien Mairal , Bertrand Thirion , Gaël Varoquaux

Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity…

Graphics · Computer Science 2016-09-02 Saad Nadeem , Arie Kaufman

Interpretable clustering algorithms aim to group similar data points while explaining the obtained groups to support knowledge discovery and pattern recognition tasks. While most approaches to interpretable clustering construct clusters…

Machine Learning · Computer Science 2024-08-27 Nakul Upadhya , Eldan Cohen

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath