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Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…
Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…
Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…
Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…
Deep neural networks have achieved state-of-the-art results in various vision and/or language tasks. Despite the use of large training datasets, most models are trained by iterating over single input-output pairs, discarding the remaining…
Successful machine learning methods require a trade-off between memorization and generalization. Too much memorization and the model cannot generalize to unobserved examples. Too much over-generalization and we risk under-fitting the data.…
We propose a supervised machine learning approach for boosting existing signal and image recovery methods and demonstrate its efficacy on example of image reconstruction in computed tomography. Our technique is based on a local nonlinear…
Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…
Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…
Foundation models have shown promise in medical imaging but remain underexplored for three-dimensional imaging modalities. No foundation model currently exists for Digital Breast Tomosynthesis (DBT), despite its use for breast cancer…
High spatial and temporal resolution across the whole brain is essential to accurately resolve neural activities in fMRI. Therefore, accelerated imaging techniques target improved coverage with high spatio-temporal resolution. Simultaneous…
Risk-adapted breast cancer screening requires robust models that leverage longitudinal imaging data. Most current deep learning models use single or limited prior mammograms and lack adaptation for real-world settings marked by imbalanced…
Deep learning techniques have emerged as a promising approach to highly accelerated MRI. However, recent reconstruction challenges have shown several drawbacks in current deep learning approaches, including the loss of fine image details…
Deep learning based computed tomography (CT) reconstruction has demonstrated outstanding performance on simulated 2D low-dose CT data. This applies in particular to domain adapted neural networks, which incorporate a handcrafted physics…
Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…
Conventional breast cancer imaging techniques are nowadays based on the use of ionising radiations or ultrasound waves for the inspection of breast areas. Nevertheless, these conventional techniques present some drawbacks related to patient…
Generating multi-contrasts/modal MRI of the same anatomy enriches diagnostic information but is limited in practice due to excessive data acquisition time. In this paper, we propose a novel deep-learning model for joint reconstruction and…
Deep learning has been shown to be useful to detect breast cancer metastases by analyzing whole slide images of sentinel lymph nodes. However, it requires extensive scanning and analysis of all the lymph nodes slides for each case. Our deep…
Purpose: To develop a deep learning-based Bayesian inference for MRI reconstruction. Methods: We modeled the MRI reconstruction problem with Bayes's theorem, following the recently proposed PixelCNN++ method. The image reconstruction from…
An optimization-based image reconstruction algorithm is developed for contrast enhanced digital breast tomosynthesis (DBT) using dual-energy scanning. The algorithm minimizes directional total variation (TV) with a data discrepancy and…