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Computations on the dendritic trees of neurons have important constraints. Voltage dependent conductances in dendrites are not similar to arbitrary direct-current generation, they are the basis for dendritic nonlinearities and they do not…

Neurons and Cognition · Quantitative Biology 2021-08-12 Ilenna Simone Jones , Konrad Paul Kording

This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…

Neurons and Cognition · Quantitative Biology 2021-06-15 Spyridon Chavlis , Panayiota Poirazi

Biological neurons are more powerful than artificial perceptrons, in part due to complex dendritic input computations. Inspired to empower the perceptron with biologically inspired features, we explore the effect of adding and tuning input…

Neural and Evolutionary Computing · Computer Science 2022-07-05 Ziwen Han , Evgeniya Gorobets , Pan Chen

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Neurons and Cognition · Quantitative Biology 2025-01-13 Clarissa Lauditi , Enrico M. Malatesta , Fabrizio Pittorino , Carlo Baldassi , Nicolas Brunel , Riccardo Zecchina

The brain can efficiently learn a wide range of tasks, motivating the search for biologically inspired learning rules for improving current artificial intelligence technology. Most biological models are composed of point neurons, and cannot…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Our understanding of biological neuronal networks has profoundly influenced the development of artificial neural networks (ANNs). However, neurons utilized in ANNs differ considerably from their biological counterparts, primarily due to the…

Neural and Evolutionary Computing · Computer Science 2025-04-09 Xundong Wu , Pengfei Zhao , Zilin Yu , Lei Ma , Ka-Wa Yip , Huajin Tang , Gang Pan , Poirazi Panayiota , Tiejun Huang

Dendrites are crucial structures for computation of an individual neuron. It has been shown that the dynamics of a biological neuron with dendrites can be approximated by artificial neural networks (ANN) with deep structure. However, it…

Neurons and Cognition · Quantitative Biology 2023-05-23 Jingyang Ma , Songting Li , Douglas Zhou

Recent advances in neuroscience have revealed many principles about neural processing. In particular, many biological systems were found to reconfigure/recruit single neurons to generate multiple kinds of decisions. Such findings have the…

Machine Learning · Computer Science 2019-05-30 Yassin Khalifa , Justin Hawks , Ervin Sejdic

Bio-inspired computing has focused on neuron and synapses with great success. However, the connections between these, the dendrites, also play an important role. In this paper, we investigate the motivation for replicating dendritic…

Neural and Evolutionary Computing · Computer Science 2023-04-06 Daniel John Mannion , Anthony Joseph Kenyon

How neurons process their inputs crucially determines the dynamics of biological and artificial neural networks. In such neural and neural-like systems, synaptic input is typically considered to be merely transmitted linearly or sublinearly…

Biological Physics · Physics 2017-06-01 David Breuer , Marc Timme , Raoul-Martin Memmesheimer

Neurons are thought of as the building blocks of excitable brain tissue. However, at the single neuron level, the neuronal membrane, the dendritic arbor and the axonal projections can also be considered an extended active medium. Active…

Neurons and Cognition · Quantitative Biology 2013-11-28 Leonardo L. Gollo , Osame Kinouchi , Mauro Copelli

The brain is a remarkably capable and efficient system. It can process and store huge amounts of noisy and unstructured information using minimal energy. In contrast, current artificial intelligence (AI) systems require vast resources for…

Neural and Evolutionary Computing · Computer Science 2023-06-16 Michalis Pagkalos , Roman Makarov , Panayiota Poirazi

Neurons are spatially extended structures that receive and process inputs on their dendrites. It is generally accepted that neuronal computations arise from the active integration of synaptic inputs along a dendrite between the input…

Neurons and Cognition · Quantitative Biology 2013-09-11 Willem A. M. Wybo , Klaus M. Stiefel , Benjamin Torben-Nielsen

Although inspired by neuronal systems in the brain, artificial neural networks generally employ point-neurons, which offer far less computational complexity than their biological counterparts. Neurons have dendritic arbors that connect to…

Emerging Technologies · Computer Science 2025-10-22 A N M Nafiul Islam , Xuezhong Niu , Jiahui Duan , Shubham Kumar , Kai Ni , Abhronil Sengupta

The brain can learn to solve a wide range of tasks with high temporal and energetic efficiency. However, most biological models are composed of simple single compartment neurons and cannot achieve the state-of-art performances of artificial…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Artificial neural networks (ANNs) are at the core of most Deep learning (DL) algorithms that successfully tackle complex problems like image recognition, autonomous driving, and natural language processing. However, unlike biological brains…

Neural and Evolutionary Computing · Computer Science 2024-09-16 Spyridon Chavlis , Panayiota Poirazi

The brain is a highly efficient system evolved to achieve high performance with limited resources. We propose that dendrites make information processing and storage in the brain more efficient through the segregation of inputs and their…

Neurons and Cognition · Quantitative Biology 2023-06-13 Roman Makarov , Michalis Pagkalos , Panayiota Poirazi

Artificial neural networks which are inspired from the learning mechanism of brain have achieved great successes in many problems, especially those with deep layers. In this paper, we propose a nucleus neural network (NNN) and corresponding…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Jia Liu , Maoguo Gong , Haibo He

Neocortical pyramidal neurons have many dendrites, and such dendrites are capable of, in isolation of one-another, generating a neuronal spike. It is also now understood that there is a large amount of dendritic growth during the first…

Neurons and Cognition · Quantitative Biology 2022-10-31 William B Levy , Robert A. Baxter

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Neurons and Cognition · Quantitative Biology 2025-12-10 Robert Worden
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