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Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic…

Computation and Language · Computer Science 2026-04-09 Feng Chen , Manas Bedmutha , Janice Sabin , Andrea Hartzler , Nadir Weibel , Trevor Cohen

PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…

Neurons and Cognition · Quantitative Biology 2023-09-20 Iman Beheshti , Samuel Booth , Ji Hyun Ko

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, affecting up to 45% of patients. They are often underdiagnosed due to overlapping motor…

This paper presents a new method for medical diagnosis of neurodegenerative diseases, such as Parkinson's, by extracting and using latent information from trained Deep convolutional, or convolutional-recurrent Neural Networks (DNNs). In…

Machine Learning · Computer Science 2019-01-24 Ilianna Kollia , Andreas-Georgios Stafylopatis , Stefanos Kollias

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Xiang Xiang , Zihan Zhang , Jing Ma , Yao Deng

Recent works in pathological speech analysis have increasingly relied on powerful self-supervised speech representations, leading to promising results. However, the complex, black-box nature of these embeddings and the limited research on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 David Gimeno-Gómez , Catarina Botelho , Anna Pompili , Alberto Abad , Carlos-D. Martínez-Hinarejos

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Christian Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

Accurately quantifying motor characteristics in Parkinson disease (PD) is crucial for monitoring disease progression and optimizing treatment strategies. The finger-tapping test is a standard motor assessment. Clinicians visually evaluate a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Tahereh Zarrat Ehsan , Michael Tangermann , Yağmur Güçlütürk , Bastiaan R. Bloem , Luc J. W. Evers

In this study we developed an automated system that evaluates speech and language features from audio recordings of neuropsychological examinations of 92 subjects in the Framingham Heart Study. A total of 265 features were used in an…

Artificial Intelligence · Computer Science 2017-10-23 Tuka Alhanai , Rhoda Au , James Glass

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

Machine Learning · Computer Science 2024-06-12 Ashwin Ram

Sensors from smart consumer devices have demonstrated high potential to serve as digital biomarkers in the identification of movement disorders in recent years. With the usage of broadly available smartwatches we have recorded participants…

Machine Learning · Computer Science 2022-05-12 Alexander Brenner , Michael Fujarski , Tobias Warnecke , Julian Varghese

Parkinsons disease (PD) is a movement disorder and the second most common neurodengerative disease but despite its relative abundance, there are no clinically accepted neuroimaging biomarkers to make prognostic predictions or differentiate…

Neurons and Cognition · Quantitative Biology 2022-06-23 Cooper J. Mellema , Kevin P. Nguyen , Alex Treacher , Aixa Andrade Hernandez , Albert A. Montillo

Detection of subtle deficits in everyday functioning due to cognitive impairment is important for early detection of neurodegenerative diseases, particularly Alzheimer's disease. However, current standards for assessment of everyday…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-13 Yasunori Yamada , Kaoru Shinkawa , Masatomo Kobayashi , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

This work aims to tackle the Parkinson's disease (PD) detection problem from the speech signal in a bilingual setting by proposing an ad-hoc dual-head deep neural architecture for type-based binary classification. One head is specialized…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-13 Moreno La Quatra , Juan Rafael Orozco-Arroyave , Marco Sabato Siniscalchi

Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The…

Neurons and Cognition · Quantitative Biology 2023-12-11 Amarpal Sahota , Amber Roguski , Matthew W. Jones , Michal Rolinski , Alan Whone , Raul Santos-Rodriguez , Zahraa S. Abdallah

Automatic detection of Parkinson's disease (PD) from speech is a promising non-invasive diagnostic tool, but it raises significant privacy concerns. Speaker anonymization mitigates these risks, but it may suppress the pathological…

Sound · Computer Science 2026-03-10 Carlos Franzreb , Francisco Teixeira , Ben Luks , Sebastian Möller , Alberto Abad

Pathological speech analysis has been of interest in the detection of certain diseases like depression and Alzheimer's disease and attracts much interest from researchers. However, previous pathological speech analysis models are commonly…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-08 Fei Yang , Xuenan Xu , Mengyue Wu , Kai Yu