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Multi-component membranes such as ternary mixtures of lipids and cholesterol can exhibit coexistence regions between two liquid phases. When such membranes adhere to a corrugated substrate, the phase separation process strongly depends on…

Soft Condensed Matter · Physics 2009-11-13 Bartosz Rozycki , Thomas R. Weikl , Reinhard Lipowsky

Growing experimental evidence indicates that topological defects could serve as organizing centers in the morphogenesis of tissues. Here, we provide a quantitative explanation for this phenomenon, rooted in the buckling theory of deformable…

Soft Condensed Matter · Physics 2022-04-21 Ludwig A. Hoffmann , Livio Nicola Carenza , Julia Eckert , Luca Giomi

Much attention has been devoted to water's metastable phase behavior, including polyamorphism (multiple amorphous solid phases), and the hypothesized liquid-liquid transition and associated critical point. However, the possible relationship…

Soft Condensed Matter · Physics 2021-06-09 Thomas E. Gartner , Salvatore Torquato , Roberto Car , Pablo G. Debenedetti

Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. First, we introduce a new theoretical framework, reaction-diffusion system on `chemical species…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko

The last decade has witnessed a rapid growth in understanding of the pivotal roles of mechanical stresses and physical forces in cell biology. As a result an integrated view of cell biology is evolving, where genetic and molecular features…

Soft Condensed Matter · Physics 2021-10-08 Amin Doostmohammadi , Benoit Ladoux

The growing need for a better understanding of nonlinear processes in plasma physics has in the last decades stimulated the development of new and more advanced data analysis techniques. This review lists some of the basic properties one…

comp-gas · Physics 2008-02-03 T. Dudok de Wit

Lumen formation plays an essential role in the morphogenesis of tissues during development. Here we review the physical principles that play a role in the growth and coarsening of lumens. Solute pumping by the cell, hydraulic flows driven…

Soft Condensed Matter · Physics 2021-07-14 Alejandro Torres-Sánchez , Max Kerr Winter , Guillaume Salbreux

Understanding the spatial organisation of the genome in the cell nucleus is one of the current grand challenges in biophysics. Certain biochemical -- or epigenetic -- marks that are deposited along the genome are thought to play an…

Soft Condensed Matter · Physics 2020-01-08 Davide Michieletto , Davide Colí , Davide Marenduzzo , Enzo Orlandini

Understanding the (de)mixing behavior of multicomponent lipid bilayers is an important step towards unraveling the nature of spatial composition heterogeneities in cellular membranes and their role in biological function. We use…

Soft Condensed Matter · Physics 2018-05-17 Shushan He , Lutz Maibaum

Understanding the partitioning of turbulent energy between ions and electrons in weakly collisional plasmas is crucial for the accurate interpretation of observations and modelling of various astrophysical phenomena. Many such plasmas are…

Plasma Physics · Physics 2024-11-20 T. Adkins , R. Meyrand , J. Squire

The existence of heterogeneity in the dynamics of supercooled liquids is believed to be one of the hallmarks of the glass transition. Intense research has been carried out in the past to understand the origin of this heterogeneity in…

Soft Condensed Matter · Physics 2020-07-01 Indrajit Tah , Smarajit Karmakar

Biological active matter like the cytoskeleton or tissues are characterized by their ability to transform chemical energy into mechanical stress. In addition, it often exhibits orientational order, which is essential for many cellular and…

Biological Physics · Physics 2025-06-05 Ludovic Dumoulin , Carles Blanch-Mercader , Karsten Kruse

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

Biological Physics · Physics 2023-08-25 Mengyang Gu , Xinyi Fang , Yimin Luo

Cholesterol plays an essential role in biological membranes and is crucial for maintaining their stability and functionality. It is necessary for a variety of membranes, including planar bilayers, liposomes, curved bilayers, nanodiscs, and…

Biomolecules · Quantitative Biology 2025-04-09 Ehsaneh Khodadadi , Ehsan Khodadadi , Parth Chaturvedi , Mahmoud Moradi

We study the effects of thermal fluctuations on symmetric tensionless heterogeneous (two-component) fluid membranes in a simple minimal model. Close to the critical point $T_c$ of the associated miscibility phase transition of the…

Statistical Mechanics · Physics 2015-06-23 Tirthankar Banerjee , Abhik Basu

In this paper, phase field models are developed for multi-component vesicle membranes with different lipid compositions and membranes with free boundary. These models are used to simulate the deformation of membranes under the elastic…

Biological Physics · Physics 2007-05-23 Xiaoqiang Wang , Qiang Du

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

The hierarchical organization of the brain is a fundamental structural principle, while brain criticality is a leading hypothesis for its collective dynamics. However, the connection between structure and signatures of criticality remains…

Neurons and Cognition · Quantitative Biology 2026-04-24 Gustavo G. Cambrainha , Daniel M. Castro , Leonardo L. Gollo , Pedro V. Carelli , Mauro Copelli

Diffusion is a fundamental phenomenon that occurs ubiquitously in nature and remains the subject of continuous research interest. Understanding diffusion is a key to understanding leaving systems. In this Chapter, I discuss diffusion of…

Soft Condensed Matter · Physics 2018-10-15 Svyatoslav Kondrat