English
Related papers

Related papers: Mediating Ribosomal Competition by Splitting Pools

200 papers

Power system networks are often modeled as homogeneous graphs, which limits the ability of graph neural network (GNN) to capture individual generator features at the same nodes. By introducing the proposed virtual node-splitting strategy,…

Systems and Control · Electrical Eng. & Systems 2025-07-22 Thuan Pham , Xingpeng Li

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Programming Languages · Computer Science 2010-11-03 Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Elena Grassi , Eva Sciacca , Salvatore Spinella , Angelo Troina

Evolutions of the trading landscape lead to the capability to exchange the same financial instrument on different venues. Because of liquidity issues, the trading firms split large orders across several trading destinations to optimize…

Trading and Market Microstructure · Quantitative Finance 2010-07-28 Sophie Laruelle , Charles-Albert Lehalle , Gilles Pagès

The interplay between energy efficiency and evolutionary mechanisms is addressed. One important question is how evolutionary mechanisms can select for the optimised usage of energy in situations where it does not lead to immediate…

Populations and Evolution · Quantitative Biology 2016-11-21 André Amado , Lenin Fernández , Weini Huang , Fernando F. Ferreira , Paulo R. A. Campos

Estimation of Distribution Algorithms (EDAs) require flexible probability models that can be efficiently learned and sampled. Restricted Boltzmann Machines (RBMs) are generative neural networks with these desired properties. We integrate an…

Neural and Evolutionary Computing · Computer Science 2014-12-01 Malte Probst , Franz Rothlauf , Jörn Grahl

This work presents RNAdiffusion, a latent diffusion model for generating and optimizing discrete RNA sequences of variable lengths. RNA is a key intermediary between DNA and protein, exhibiting high sequence diversity and complex…

Machine Learning · Computer Science 2024-10-03 Kaixuan Huang , Yukang Yang , Kaidi Fu , Yanyi Chu , Le Cong , Mengdi Wang

Gene prioritization (identifying genes potentially associated with a biological process) is increasingly tackled with Artificial Intelligence. However, existing methods struggle with the high dimensionality and incomplete labelling of…

We apply a stochastic method of minimizing the ground state energy in variational calculations of light nuclei using the Refined Resonating Group Model (RRGM). The method utilizes a bit representation of the width parameters to be varied.…

Nuclear Theory · Physics 2008-11-26 Christian Winkler , Hartmut M. Hofmann

In this work, a new hybrid predictive Reduced Order Model (ROM) is proposed to solve reacting flow problems. This algorithm is based on a dimensionality reduction using Proper Orthogonal Decomposition (POD) combined with deep learning…

Machine Learning · Computer Science 2023-01-25 Adrián Corrochano , Rodolfo S. M. Freitas , Alessandro Parente , Soledad Le Clainche

As a consequence of the rugged landscape of RNA molecules their folding is described by the kinetic partitioning mechanism according to which only a small fraction ($\phi_F$) reaches the folded state while the remaining fraction of…

Biomolecules · Quantitative Biology 2017-01-24 Changbong Hyeon , D. Thirumalai

The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

Biological Physics · Physics 2018-11-02 Yuichi Togashi

In this paper, we generate a transmit power pool (PP) for Internet of things (IoT) networks with semi-grant-free non-orthogonal multiple access (SGF-NOMA) via multi-agent deep reinforcement learning (MA-DRL) to enable open loop power…

Information Theory · Computer Science 2022-06-03 Muhammad Fayaz , Wenqiang Yi , Yuanwei Liu , Arumugam Nallanathan

We consider the shape optimization of flow fields for electrochemical cells. Our goal is to improve the cell by modifying the shape of its flow field. To do so, we introduce simulation models of the flow field with and without the porous…

This article presents a physical biology approach to understanding organization and segregation of bacterial chromosomes. The author uses a "piston" analogy for bacterial chromosomes in a cell, which leads to a phase diagram for the…

Subcellular Processes · Quantitative Biology 2010-06-01 Suckjoon Jun

Biological and living organisms sense and process information from their surroundings, typically having access only to a subset of external observables for a limited amount of time. In this work, we uncover how biological systems can…

Statistical Mechanics · Physics 2024-10-10 Giorgio Nicoletti , Daniel Maria Busiello

Many biochemical applications such as molecular property prediction require models to generalize beyond their training domains (environments). Moreover, natural environments in these tasks are structured, defined by complex descriptors such…

Machine Learning · Computer Science 2020-10-08 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Many fundamental biological processes are regulated by protein-DNA complexes called {\it synaptosomes}, which possess multiple interaction sites. Despite the critical importance of synaptosomes, the mechanisms of their formation remain not…

Soft Condensed Matter · Physics 2020-01-29 Cayke Felipe , Jaeoh Shin , Yulia Loginova , Anatoly B. Kolomeisky

Channel proteins, that selectively conduct molecules across cell membranes, often exhibit an asymmetric structure. By means of a stochastic model, we argue that channel asymmetry in the presence of non-equilibrium fluctuations, fueled by…

Biological Physics · Physics 2007-05-23 Ioan Kosztin , Klaus Schulten

We develop Random Batch Methods for interacting particle systems with large number of particles. These methods use small but random batches for particle interactions, thus the computational cost is reduced from $O(N^2)$ per time step to…

Numerical Analysis · Mathematics 2019-09-25 Shi Jin , Lei Li , Jian-Guo Liu

The biological world, especially its majority microbial component, is strongly interacting and may be dominated by collective effects. In this review, we provide a brief introduction for statistical physicists of the way in which living…

Populations and Evolution · Quantitative Biology 2015-05-20 Nicholas Chia , Nigel Goldenfeld