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Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

In this paper we made a review of some papers about probabilistic regulatory networks (PRN), in particular we introduce our concept of homomorphisms of PRN with an example of projection of a regulatory network to a smaller one. We apply the…

Cell Behavior · Quantitative Biology 2007-08-20 Maria A. Avino-Diaz

Stochastic processes that involve the creation of objects and relations over time are widespread, but relatively poorly studied. For example, accurate fault diagnosis in factory assembly processes requires inferring the probabilities of…

Artificial Intelligence · Computer Science 2011-09-13 P. Domingos , S. Sanghai , D. Weld

We investigate how classifiers for Boolean networks (BNs) can be constructed and modified under constraints. A typical constraint is to observe only states in attractors or even more specifically steady states of BNs. Steady states of BNs…

Commutative Algebra · Mathematics 2021-08-20 Robert Schwieger , Matías R. Bender , Heike Siebert , Christian Haase

We propose a novel data-driven stochastic model predictive control framework for uncertain linear systems with noisy output measurements. Our approach leverages multi-step predictors to efficiently propagate uncertainty, ensuring chance…

Systems and Control · Electrical Eng. & Systems 2025-03-18 Haldun Balim , Andrea Carron , Melanie N. Zeilinger , Johannes Köhler

This article is set in the field of regulation networks modeled by discrete dynamical systems. It focuses on Boolean automata networks. In such networks, there are many ways to update the states of every element. When this is done…

Discrete Mathematics · Computer Science 2015-03-19 Mathilde Noual

In recent years, leveraging parallel and distributed computational resources has become essential to solve problems of high computational cost. Bayesian optimization (BO) has shown attractive results in those expensive-to-evaluate problems…

Machine Learning · Statistics 2020-06-25 Masahiro Nomura

In this paper, we propose a generalization of the Batch Normalization (BN) algorithm, diminishing batch normalization (DBN), where we update the BN parameters in a diminishing moving average way. BN is very effective in accelerating the…

Machine Learning · Computer Science 2019-02-20 Yintai Ma , Diego Klabjan

In this paper, we focus on the study of quotients of Boolean control networks (BCNs) with the motivation that they might serve as smaller models that still carry enough information about the original network. Given a BCN and an equivalence…

Optimization and Control · Mathematics 2020-07-13 Rui Li , Qi Zhang , Tianguang Chu

We consider a problem from biological network analysis of determining regions in a parameter space over which there are multiple steady states for positive real values of variables and parameters. We describe multiple approaches to address…

Symbolic Computation · Computer Science 2019-11-25 R. Bradford , J. H. Davenport , M. England , H. Errami , V. Gerdt , D. Grigoriev , C. Hoyt , M. Kosta , O. Radulescu , T. Sturm , A. Weber

Port-Hamiltonian neural networks (pHNNs) are emerging as a powerful modeling tool that integrates physical laws with deep learning techniques. While most research has focused on modeling the entire dynamics of interconnected systems, the…

Systems and Control · Electrical Eng. & Systems 2024-11-11 G. J. E. van Otterdijk , S. Moradi , S. Weiland , R. Tóth , N. O. Jaensson , M. Schoukens

We consider the problem of learning structures and parameters of Continuous-time Bayesian Networks (CTBNs) from time-course data under minimal experimental resources. In practice, the cost of generating experimental data poses a bottleneck,…

Machine Learning · Statistics 2022-01-12 Dominik Linzner , Heinz Koeppl

Intracellular networks process cellular-level information and control cell fate. They can be computationally modeled using Boolean networks, which are implicit-time causal models of discrete binary events. These networks can be embedded in…

Molecular Networks · Quantitative Biology 2025-01-28 John Metzcar , Katie Pletz , Heber L. Rocha , Jordan C Rozum

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

Modelling, parameter identification, and simulation play an important role in systems biology. Usually, the goal is to determine parameter values that minimise the difference between experimental measurement values and model predictions in…

Mathematical Software · Computer Science 2013-04-10 Thomas Dierkes , Susanna Röblitz , Moritz Wade , Peter Deuflhard

Cognitive diagnostic assessment aims to measure specific knowledge structures in students. To model data arising from such assessments, cognitive diagnostic models with discrete latent variables have gained popularity in educational and…

Methodology · Statistics 2023-08-25 Seunghyun Lee , Yuqi Gu

The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of…

Systems and Control · Computer Science 2018-09-11 Anuj Deshpande , Ritwik Kumar Layek

We present a method based on symbolic dynamics for the detection of synchronization in networks of coupled maps and distinguishing between chaotic and random iterations. The symbolic dynamics are defined using special partitions of the…

Chaotic Dynamics · Physics 2007-05-23 Sarika Jalan , Fatihcan M. Atay , Jürgen Jost

A key issue in physical-layer network coding (PNC) is how to deal with the asynchrony between signals transmitted by multiple transmitters. That is, symbols transmitted by different transmitters could arrive at the receiver with symbol…

Information Theory · Computer Science 2015-03-19 Lu Lu , Soung Chang Liew

In processing and manufacturing industries, there has been a large push to produce higher quality products and ensure maximum efficiency of processes. This requires approaches to effectively detect and resolve disturbances to ensure optimal…

Machine Learning · Statistics 2021-02-05 Weike Sun , Antonio R. C. Paiva , Peng Xu , Anantha Sundaram , Richard D. Braatz