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In this thesis we explore using the D-Wave Advantage 4.1 quantum annealer to sample from quantum Boltzmann distributions and train quantum Boltzmann machines (QBMs). We focus on the real-world problem of using QBMs as generative models to…

Quantum Physics · Physics 2023-02-01 Cameron Perot

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

Quantum algorithms based on quantum kernel methods have been investigated previously [1]. A quantum advantage is derived from the fact that it is possible to construct a family of datasets for which, only quantum processing can recognise…

Quantum Physics · Physics 2024-05-08 Sanjeev Naguleswaran

This paper investigates the basic behavior and performance of simulated quantum annealing (QA) in comparison with classical annealing (CA). Three simple one dimensional case study systems are considered, namely a parabolic well, a double…

Other Condensed Matter · Physics 2009-11-11 Lorenzo Stella , Giuseppe E. Santoro , Erio Tosatti

Gradient descent methods have long been the de facto standard for training deep neural networks. Millions of training samples are fed into models with billions of parameters, which are slowly updated over hundreds of epochs. Recently, it's…

Machine Learning · Computer Science 2023-02-14 Tim Whitaker

This work considers a challenging Deep Neural Network(DNN) quantization task that seeks to train quantized DNNs without involving any full-precision operations. Most previous quantization approaches are not applicable to this task since…

Neural and Evolutionary Computing · Computer Science 2022-05-24 Fu Peng , Shengcai Liu , Ning Lu , Ke Tang

Recent developments in quantum annealing techniques have been indicating potential advantage of quantum annealing for solving NP-hard optimization problems. In this article we briefly indicate and discuss the beneficial features of quantum…

Statistical Mechanics · Physics 2015-06-22 Sudip Mukherjee , Bikas K. Chakrabarti

Over the past decade, machine learning revolutionized vision-based quality assessment for which convolutional neural networks (CNNs) have now become the standard. In this paper, we consider a potential next step in this development and…

Quantum Physics · Physics 2022-06-09 Barry D. Reese , Marek Kowalik , Christian Metzl , Christian Bauckhage , Eldar Sultanow

In a recent study (Ref. [1]), quantum annealing was reported to exhibit a scaling advantage for approximately solving Quadratic Unconstrained Binary Optimization (QUBO). However, this claim critically depends on the choice of classical…

Quantum Physics · Physics 2025-05-29 J. Pawlowski , P. Tarasiuk , J. Tuziemski , L. Pawela , B. Gardas

We propose Deep Companion Learning (DCL), a novel training method for Deep Neural Networks (DNNs) that enhances generalization by penalizing inconsistent model predictions compared to its historical performance. To achieve this, we train a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Ruizhao Zhu , Venkatesh Saligrama

Quantum annealers aim at solving non-convex optimization problems by exploiting cooperative tunneling effects to escape local minima. The underlying idea consists in designing a classical energy function whose ground states are the sought…

Quantum Physics · Physics 2018-09-12 Carlo Baldassi , Riccardo Zecchina

Guided wave testing is a popular approach for monitoring the structural integrity of infrastructures. We focus on the primary task of damage detection, where signal processing techniques are commonly employed. The detection performance is…

Signal Processing · Electrical Eng. & Systems 2022-02-02 Ishan D. Khurjekar , Joel B. Harley

Recently, researchers have proposed many deep generative models, including generative adversarial networks(GANs) and denoising diffusion models. Although significant breakthroughs have been made and empirical success has been achieved with…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Chang Wan , Ming-Hsuan Yang , Minglu Li , Yunliang Jiang , Zhonglong Zheng

Genetic algorithms, which mimic evolutionary processes to solve optimization problems, can be enhanced by using powerful semi-local search algorithms as mutation operators. Here, we introduce reverse quantum annealing, a class of quantum…

This Thesis delves into the development and implementation of quantum algorithms using the digital-analog quantum computing (DAQC) paradigm. It provides a comparative analysis of the performance of DAQC versus traditional digital…

Quantum Physics · Physics 2024-01-22 Ana Martin

We revisit the evidence for quantum annealing in the D-Wave One device (DW1) based on the study of random Ising instances. Using the probability distributions of finding the ground states of such instances, previous work found agreement…

Quantum Physics · Physics 2015-02-10 Tameem Albash , Troels F. Rønnow , Matthias Troyer , Daniel A. Lidar

We design a quantum version of neural networks with sinusoidal activation functions and compare its performance to the classical case. We create a general quantum sine circuit implementing a discretised sinusoidal activation function. Along…

Quantum Physics · Physics 2025-07-01 Zujin Wen , Jin-Long Huang , Oscar Dahlsten

Apprenticeship learning is a method commonly used to train artificial intelligence systems to perform tasks that are challenging to specify directly using traditional methods. Based on the work of Abbeel and Ng (ICML'04), we present a…

Quantum Physics · Physics 2026-03-13 Andris Ambainis , Debbie Lim

This work presents a fully quantum approach to support vector machine (SVM) learning by integrating gate-based quantum kernel methods with quantum annealing-based optimization. We explore the construction of quantum kernels using various…

Quantum Physics · Physics 2025-09-08 Mario Bifulco , Luca Roversi

We investigate a hybrid quantum-classical solution method to the mean-variance portfolio optimization problems. Starting from real financial data statistics and following the principles of the Modern Portfolio Theory, we generate…

Quantum Physics · Physics 2019-07-01 Davide Venturelli , Alexei Kondratyev
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