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Feature matching and finding correspondences between endoscopic images is a key step in many clinical applications such as patient follow-up and generation of panoramic image from clinical sequences for fast anomalies localization.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Manel Farhat , Houda Chaabouni-Chouayakh , Achraf Ben-Hamadou

The ability to computationally generate novel yet physically foldable protein structures could lead to new biological discoveries and new treatments targeting yet incurable diseases. Despite recent advances in protein structure prediction,…

Biomolecules · Quantitative Biology 2022-11-28 Kevin E. Wu , Kevin K. Yang , Rianne van den Berg , James Y. Zou , Alex X. Lu , Ava P. Amini

Convolutional networks have marked their place over the last few years as the best performing model for various visual tasks. They are, however, most suited for supervised learning from large amounts of labeled data. Previous attempts have…

Machine Learning · Computer Science 2018-12-05 Elad Hoffer , Itay Hubara , Nir Ailon

We propose a new deep network structure for unconstrained face recognition. The proposed network integrates several key components together in order to characterize complex data distributions, such as in unconstrained face images. Inspired…

Computer Vision and Pattern Recognition · Computer Science 2019-03-20 Qiangchang Wang , Guodong Guo , Mohammad Iqbal Nouyed

Establishing dense correspondences across image pairs is essential for tasks such as shape reconstruction and robot manipulation. In the challenging setting of matching across different categories, the function of an object, i.e., the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Stefan Stojanov , Linan Zhao , Yunzhi Zhang , Daniel L. K. Yamins , Jiajun Wu

Learning automatically the structure of object categories remains an important open problem in computer vision. In this paper, we propose a novel unsupervised approach that can discover and learn landmarks in object categories, thus…

Computer Vision and Pattern Recognition · Computer Science 2017-08-08 James Thewlis , Hakan Bilen , Andrea Vedaldi

Unsupervised learning from visual data is one of the most difficult challenges in computer vision, being a fundamental task for understanding how visual recognition works. From a practical point of view, learning from unsupervised visual…

Computer Vision and Pattern Recognition · Computer Science 2017-04-03 Ioana Croitoru , Simion-Vlad Bogolin , Marius Leordeanu

Studying the function of proteins is important for understanding the molecular mechanisms of life. The number of publicly available protein structures has increasingly become extremely large. Still, the determination of the function of a…

Machine Learning · Computer Science 2018-03-02 Wajdi Dhifli , Abdoulaye Baniré Diallo

Learning physically structured representations of dynamical systems that include contact between different objects is an important problem for learning-based approaches in robotics. Black-box neural networks can learn to approximately…

Machine Learning · Computer Science 2022-08-16 Andreas Hochlehnert , Alexander Terenin , Steindór Sæmundsson , Marc Peter Deisenroth

Feature selection methods have an important role on the readability of data and the reduction of complexity of learning algorithms. In recent years, a variety of efforts are investigated on feature selection problems based on unsupervised…

Machine Learning · Computer Science 2019-12-12 Mohsen Ghassemi Parsa , Hadi Zare , Mehdi Ghatee

Functional protein-protein interactions are crucial in most cellular processes. They enable multi-protein complexes to assemble and to remain stable, and they allow signal transduction in various pathways. Functional interactions between…

Biomolecules · Quantitative Biology 2018-11-14 Anne-Florence Bitbol

Proteins need to selectively interact with specific targets among a multitude of similar molecules in the cell. But despite a firm physical understanding of binding interactions, we lack a general theory of how proteins evolve high…

Biomolecules · Quantitative Biology 2022-09-28 John M McBride , Jean-Pierre Eckmann , Tsvi Tlusty

Deep neural networks need a big amount of training data, while in the real world there is a scarcity of data available for training purposes. To resolve this issue unsupervised methods are used for training with limited data. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-02-10 Sayed Hashim , Muhammad Ali

Compound-Protein Interaction (CPI) prediction aims to predict the pattern and strength of compound-protein interactions for rational drug discovery. Existing deep learning-based methods utilize only the single modality of protein sequences…

Biomolecules · Quantitative Biology 2024-02-14 Lirong Wu , Yufei Huang , Cheng Tan , Zhangyang Gao , Bozhen Hu , Haitao Lin , Zicheng Liu , Stan Z. Li

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Estimating correspondences between pairs of non-rigid deformable 3D shapes remains a significant challenge in computer vision and graphics. While deep functional map methods have become the go-to solution for addressing this problem, they…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Feifan Luo , Hongyang Chen

In the course of evolution, proteins show a remarkable conservation of their three-dimensional structure and their biological function, leading to strong evolutionary constraints on the sequence variability between homologous proteins. Our…

Quantitative Methods · Quantitative Biology 2014-04-07 Carlo Baldassi , Marco Zamparo , Christoph Feinauer , Andrea Procaccini , Riccardo Zecchina , Martin Weigt , Andrea Pagnani

Deep neural networks proved to be a very useful and powerful tool with many practical applications. They especially excel at learning from large data sets with labeled samples. However, in order to achieve good learning results, the network…

Neural and Evolutionary Computing · Computer Science 2018-01-03 Włodzimierz Funika , Paweł Koperek

The identification of novel drug-target (DT) interactions is a substantial part of the drug discovery process. Most of the computational methods that have been proposed to predict DT interactions have focused on binary classification, where…

Machine Learning · Statistics 2019-02-06 Hakime Öztürk , Elif Ozkirimli , Arzucan Özgür

Deep graph embedding is an important approach for community discovery. Deep graph neural network with self-supervised mechanism can obtain the low-dimensional embedding vectors of nodes from unlabeled and unstructured graph data. The…

Social and Information Networks · Computer Science 2021-02-09 Shuliang Xu , Shenglan Liu , Lin Feng