Related papers: Interferometric speckle visibility spectroscopy (I…
Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…
Diffuse correlation spectroscopy (DCS) is a noninvasive optical technique that probes microvascular blood flow in deep tissues. Here, we present and validate a new on-chip hardware correlator for high-speed DCS measurements. The correlator…
Traditional detection methods of C-reactive protein (CRP) inflammation biomarker, in blood are expensive, time-consuming and labor-intensive. Such existing point-of-care CRP detection devices remain invasive, since they need blood sampling…
Imaging the brain vasculature can be critical for cerebral perfusion monitoring in the context of neurocritical care. Although ultrasensitive Doppler (UD) can provide good sensitivity to cerebral blood volume (CBV) in a large field of view,…
Increasing demand for understanding the vast heterogeneity of cellular phenotypes has driven the development of imaging flow cytometry (IFC), that combines features of flow cytometry with fluorescence and bright field microscopy. IFC…
To address many of the deficiencies in optical neuroimaging technologies such as poor spatial resolution, time-consuming reconstruction, low penetration depth, and contact-based measurement, a novel, noncontact, time-resolved laser speckle…
This paper presents a non-contact vital signs (respiration and heartbeat) monitoring system that utilizes visible light sensing (VLS) technology. We have for the first time demonstrated the ability to wirelessly (non-contact) sense vital…
Perfusion MRI is an important modality in many brain imaging protocols, since it probes cerebrovascular changes in aging and many diseases; however, it may not be always available. Here we introduce a method that seeks to estimate regional…
The impulse response function (IRF) of a localized bolus in cerebral blood flow codes important information on the tissue type. It is indirectly accessible both from MR- and CT-imaging methods, at least in principle. In practice, however,…
Circulatory system abnormalities might be an indicator of diseases or tissue damage. Early detection of vascular abnormalities might have an important role during treatment and also raise the patient's awarenes. Current detection methods…
To understand the scientific imaging capability, one must characterize the intra-pixel sensitivity variation (IPSV) of the CMOS image sensor. Extracting an IPSV map contributes to an improved detector calibration that allows to eliminate…
The Chinese Space Station Survey Telescope (CSST) is a next-generation Stage-IV facility renowned for its wide field of view, high image quality, and multi-band observational capabilities. Among the five instruments onboard the CSST, the…
Contrary to conventional frame-based imaging, event-based vision (EBV) or dynamic vision sensing (DVS) asynchronously records binary signals of intensity changes for given pixels with microsecond resolution. The present work explores the…
Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…
Dynamic and precise measurement of cerebral blood flow velocity is crucial in neuroscience and the diagnosis of cerebrovascular diseases. Traditional color Doppler ultrasound can only measure the velocity component along the ultrasound…
This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…
The paper addresses the shortcoming of current event-based vision (EBV) sensors in the context of particle imaging. Latency is introduced both on the pixel level as well as during read-out from the array and results in systemic timing…
Intravascular ultrasound (IVUS) is the preferred modality for capturing real-time and high resolution cross-sectional images of the coronary arteries, and evaluating the stenosis. Accurate and real-time segmentation of IVUS images involves…
This paper addresses the problem of high-resolution Doppler blood flow estimation from an ultrafast sequence of ultrasound images. Formulating the separation of clutter and blood components as an inverse problem has been shown in the…
Intrathecal (IT) injection is an effective way to deliver drugs to the brain bypassing the blood-brain barrier. To evaluate and optimize IT drug delivery, it is necessary to understand the cerebrospinal fluid (CSF) dynamics in the central…