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Related papers: Equilibrium Equality for Free Energy Difference

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The accurate estimation of free energy differences between two states is a long-standing challenge in molecular simulations. Traditional approaches generally rely on sampling multiple intermediate states to ensure sufficient overlap in…

Statistical Mechanics · Physics 2026-03-17 Maximilian Schebek , Jiajun He , Emil Hoffmann , Yuanqi Du , Frank Noé , Jutta Rogal

Most natural and engineered processes, such as biomolecular reactions, protein folding, and population dynamics, occur far from equilibrium and, therefore, cannot be treated within the framework of classical equilibrium thermodynamics. The…

Soft Condensed Matter · Physics 2016-01-07 Aykut Argun , Ali-Reza Moradi , Erçağ Pince , Gokhan Baris Bagci , Giovanni Volpe

In this paper, we study Jarzynski's equality and fluctuation theorems for diffusion processes. While some of the results considered in the current work are known in the (mainly physics) literature, we review and generalize these…

Mathematical Physics · Physics 2019-04-09 Carsten Hartmann , Christof Schuette , Wei Zhang

The past two decades witnessed important developments in the field of non-equilibrium statistical mechanics. Among these developments, the Jarzynski equality, being a milestone following the landmark work of Clausius and Kelvin, stands out.…

Quantum Physics · Physics 2015-06-22 Shuoming An , Jing-Ning Zhang , Mark Um , Dingshun Lv , Yao Lu , Junhua Zhang , Zhang-qi Yin , H. T. Quan , Kihwan Kim

A simple model featuring a double well potential is used to represent a liquid that is quenched from an ergodic state into a history dependent glassy state. Issues surrounding the application of the Jarzynski Equality to glass formation are…

Statistical Mechanics · Physics 2012-09-11 Stephen R. Williams , Debra J. Searles , Denis J. Evans

With the traditional equilibrium molecular simulations, it is usually difficult to efficiently visit the whole conformational space in complex systems, which are separated into some metastable conformational regions by high free energy…

Soft Condensed Matter · Physics 2019-08-17 Cheng Yang , Biao Wan , Shun Xu , Yanting Wang , Xin Zhou

The Jarzynski Equality is a well-known and widely used identity, relating the free energy difference between two states of a system to the work done over some arbitrary, nonequilibrium transformation between the two states. Despite being…

Statistical Mechanics · Physics 2018-12-18 Stuart J. Davie , Owen G. Jepps , Lamberto Rondoni , James C. Reid , Debra J. Searles

Two identities in statistical mechanics involving entropy differences (or ratios of density of states) at constant energy are derived. The first provides a nontrivial extension of the Jarzynski equality to the microcanonical ensemble [C.…

Statistical Mechanics · Physics 2009-11-10 Artur B. Adib

The equilibrium free energy landscape of an off-lattice model protein as a function of an internal (reaction) coordinate is reconstructed from out-of-equilibrium mechanical unfolding manipulations. This task is accomplished via two…

Statistical Mechanics · Physics 2007-10-17 Alberto Imparato , Stefano Luccioli , Alessandro Torcini

The computation of free energy differences through an exponential weighting of out of equilibrium paths (known as the Jarzynski equality) is often used for transitions between states described by an external parameter $\lambda$ in the…

Statistical Mechanics · Physics 2015-06-25 Tony Lelievre , Mathias Rousset , Gabriel Stoltz

We derive a general information-theoretic equality for a system undergoing two projective measurements separated by a general temporal evolution. The equality implies the non-negativity of the mutual information between the measurement…

Quantum Physics · Physics 2015-06-04 Vlatko Vedral

Recent years have witnessed major advances in our understanding of nonequilibrium processes. The Jarzynski equality, for example, provides a link between equilibrium free energy differences and finite-time, nonequilibrium dynamics. We…

Statistical Mechanics · Physics 2016-04-27 Dibyendu Mandal , Michael R. DeWeese

In this paper we develop a generalized formalism for equilibrium thermodynamic systems when an information is shared between the system and the reservoir. The information results in a correction to the entropy of the system. This extension…

Statistical Mechanics · Physics 2013-05-10 Alessio Gagliardi , Aldo Di Carlo

Energy-based models (EBMs) are generative models inspired by statistical physics with a wide range of applications in unsupervised learning. Their performance is best measured by the cross-entropy (CE) of the model distribution relative to…

Machine Learning · Computer Science 2023-12-14 Davide Carbone , Mengjian Hua , Simon Coste , Eric Vanden-Eijnden

The Jarzynski equality and the fluctuation theorem relate equilibrium free energy differences to non-equilibrium measurements of the work. These relations extend to single-molecule experiments that have probed the finite-time thermodynamics…

Statistical Mechanics · Physics 2008-08-30 Paul Maragakis , Felix Ritort , Carlos Bustamante , Martin Karplus , Gavin E. Crooks

The theory of phenomenological Non-equilibrium Thermodynamics is extended by includimg stochastic processes in order to account for recently derived thermodynamical relations such as the Jarzynski equality. Four phenomenological axioms are…

Chaotic Dynamics · Physics 2016-07-20 Wolfgang Muschik

We study the statistics of energy fluctuations in a three-level quantum system subject to a sequence of projective quantum measurements. We check that, as expected, the quantum Jarzynski equality holds provided that the initial state is…

Quantum Physics · Physics 2020-03-25 Guido Giachetti , Stefano Gherardini , Andrea Trombettoni , Stefano Ruffo

The celebrated exchange fluctuation theorem -- proposed by Jarzynski and W\'ozcik, (Phys Rev. Lett. 92, 230602 (2004)) for heat exchange between two systems in thermal equilibrium at different temperatures -- is explored here for quantum…

Quantum Physics · Physics 2021-11-05 A R Usha Devi , Sudha , A. K. Rajagopal , A. M. Jayannavar

A quantum analogue of the Jarzynski equality is constructed. This equality connects an ensemble average of exponentiated work with the Helmholtz free-energy difference in a nonequilibrium switching process subject to a thermal heat bath. To…

Statistical Mechanics · Physics 2009-10-31 Satoshi Yukawa

A methodology for calculating the contribution of charged defects to the configurational free energy of an ionic crystal is introduced. The temperature-independent Wang-Landau Monte Carlo technique is applied to a simple model of a solid…

Materials Science · Physics 2015-06-16 Robert M. Horton , Andrew J. Haslam , Amparo Galindo , George Jackson , Michael W. Finnis