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Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Flow-based microfluidic biochips are widely used in lab- on-a-chip experiments. In these chips, devices such as mixers and detectors connected by micro-channels execute specific operations. Intermediate fluid samples are saved in storage…

Emerging Technologies · Computer Science 2017-05-16 Tsun-Ming Tseng , Bing Li , Tsung-Yi Ho , Ulf Schlichtmann

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

Tumor organoid-on-a-chip platforms represent a cutting-edge fusion of patient-derived organoids with microfluidic technologies, offering unprecedented capabilities for personalized cancer research. These systems overcome limitations of…

Tissues and Organs · Quantitative Biology 2025-07-30 Keyvan Alavi

Application of Microelectronic to bioanalysis is an emerging field which holds great promise. From the standpoint of electronic and system design, biochips imply a radical change of perspective, since new, completely different constraints…

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Several high-performance lab instruments suitable for manual assembly have been developed using low-pin-count 32-bit microcontrollers that communicate with an Android tablet via a USB interface. A single Android tablet app accommodates…

Instrumentation and Detectors · Physics 2015-06-16 E. E. Eyler

Printed and flexible electronics (PFE) have emerged as the ubiquitous solution for application domains at the extreme edge, where the demands for low manufacturing and operational cost cannot be met by silicon-based computing. Built on…

Hardware Architecture · Computer Science 2025-05-02 Mehdi B. Tahoori , Emre Ozer , Georgios Zervakis , Konstantinos Balaskas , Priyanjana Pal

Digital MemComputing machines (DMMs), which employ nonlinear dynamical systems with memory (time non-locality), have proven to be a robust and scalable unconventional computing approach for solving a wide variety of combinatorial…

Emerging Technologies · Computer Science 2024-07-16 Yuan-Hang Zhang , Massimiliano Di Ventra

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

This paper enumerates new architecture of low power dual-edge triggered Flip-Flop (DETFF) designed at 180nm CMOS technology. In DETFF same data throughput can be achieved with half of the clock frequency as compared to single edge triggered…

Other Computer Science · Computer Science 2014-12-30 Anurag , Gurmohan Singh , V. Sulochana

Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…

Applied Physics · Physics 2020-12-02 Taiki Takemuro , Hideaki Yamamoto , Shigeo Sato , Ayumi Hirano-Iwata

The dynamical properties of classical fluids at pico-liter scale attract experimentally and theoretically much attention in the soft-matter and biophysics communities, due to the appearance of the microfluidics, also called 'lab-on-a-chip',…

Statistical Mechanics · Physics 2007-05-23 F. Penna , P. Tarazona

In this ongoing work, we are interested in multiprocessor energy efficient systems, where task durations are not known in advance, but are know stochastically. More precisely, we consider global scheduling algorithms for frame-based…

Operating Systems · Computer Science 2008-09-25 Vandy Berten , Joël Goossens

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and…

As microfluidics-based biochips become more complex, manufacturing yield will have significant influence on production volume and product cost. We propose an interstitial redundancy approach to enhance the yield of biochips that are based…

Hardware Architecture · Computer Science 2011-11-09 Fei Su , Krishnendu Chakrabarty , Vamsee K. Pamula

Physically Unclonable Functions (PUFs) are used for securing electronic devices across the implementation spectrum ranging from Field Programmable Gate Array (FPGA) to system on chips (SoCs). However, existing PUF implementations often…

Cryptography and Security · Computer Science 2023-03-31 Christopher Vega , Shubhra Deb Paul , Patanjali SLPSK , Swarup Bhunia

Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational…

Fluid Dynamics · Physics 2024-11-05 Maria Emmerich , Florina Costamoling , Robert Wille

The use of asynchronous design approaches to construct digital signal processing (DSP) systems is a rapidly growing research area driven by a wide range of emerging energy constrained applications such as wireless sensor network, portable…

Hardware Architecture · Computer Science 2016-03-16 Basel Halak , Hsien-Chih Chiu

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant