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Protein phosphorylation provides a dynamic readout of cellular signaling yet remains difficult to detect at low abundance and stoichiometry. Single-molecule surface-enhanced Raman spectroscopy (SM-SERS) using particle-in-pore plasmonic…

Mesoscale and Nanoscale Physics · Physics 2026-04-09 Mulusew W. Yaltaye , Yingqi Zhao , Kuo Zhan , Vahid Farrahi , Jian-An Huang

The paper reports on the optical detection and spectroscopy of ultracold atoms near a gold surface. A probe light field is used to excite surface plasmon polaritons. The refractive index of the atomic gas shifts the plasmon resonance and…

Quantum Physics · Physics 2021-01-13 Matthias Mildner , Claus Zimmermann , Sebastian Slama

The inelastic scattering of electrons is one route to study the vibrational and electronic properties of materials. Such experiments, also called electron energy-loss spectroscopy, are particularly useful for the investigation of the…

Materials Science · Physics 2014-06-24 Friedrich Roth , Andreas König , Jörg Fink , Bernd Büchner , Martin Knupfer

Methods to increase the light scattered from small particles can help improve the sensitivity of many sensing techniques. Here, we investigate the role multiple scattering plays in perturbing the scattered signal when a particle is added to…

Optics · Physics 2021-08-03 Joel Berk , Matthew R. Foreman

Surface plasmon scattering by 1D indentations and protrusions is examined, mainly in the optical regime. The width of the defects is fixed, while its height is varied. Both individual and arrays of defects are considered. Protrusions mainly…

Mesoscale and Nanoscale Physics · Physics 2010-09-22 Giovanni Brucoli , Luis Martín Moreno

The experimental demonstration and characterization is made of the plasmon-mediated resonant transmission through an embedded undulated continuous thin metal film under normal incidence. 1D undulations are shown to enable a spatially…

Particle tracking is a key to single-particle-level confocal microscopy observation of colloidal suspensions, emulsions, and granular matter. The conventional tracking method has not been able to provide accurate information on the size of…

Soft Condensed Matter · Physics 2013-01-31 Mathieu Leocmach , Hajime Tanaka

Interferometric scattering (iSCAT) microscopy is currently among the most powerful techniques available for achieving high-sensitivity single-particle localization. This capability is realized through homodyne detection, where interference…

Optics · Physics 2024-10-08 Nathan J. Brooks , Chih-Chen Liu , Chia-Lung Hsieh

Surface plasmon polaritons scattering from 2D subwavelength silicon wires is investigated using finite difference time domain method. It is shown that coupling an incident surface plasmon polariton to inter-cavity modes of the particle can…

Surface plasmon resonances (SPRs) are crucial for confining light beyond the diffraction limit, yet heavy metal losses often limit their spectral localization. Here, we propose a practical strategy for enabling the spectral localization of…

This work continues the development of the raytracing method of [1] for computing the scattered fields from metasurfaces characterized by locally periodic reflection and transmission coefficients. In this work, instead of describing the…

Optics · Physics 2022-02-16 Scott Stewart , Yvo L. C. de Jong , Tom J. Smy , Shulabh Gupta

Tracking single fluorescent molecules has offered resolution into dynamic molecular processes at the single-molecule level. This perspective traces the evolution of single-molecule tracking, highlighting key developments across various…

Biological Physics · Physics 2026-02-24 Lance W. Q. Xu , Steve Pressé

Light scattering by small particles has a long and interesting history in physics. Nonetheless, it continues to surprise with new insights and applications. This includes new discoveries, such as novel plasmonic effects, as well as exciting…

Optics · Physics 2014-07-10 Xiaofeng Fan , Weitao Zheng , David J. Singh

Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…

Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for quantitative bond-selective imaging of single-biomolecule…

Surface plasmons are collective oscillations of electrons in metals or semiconductors enabling confinement and control of electromagnetic energy at subwavelength scales. Rapid progress in plasmonics has largely relied on advances in device…

Here, we present a concept based on the realization that a complex medium can be used as a simple interferometer. Changes in the wavefront of an incident coherent beam can be retrieved by analyzing changes in speckle patterns when the beam…

Optics · Physics 2016-10-07 KyungDuk Kim , HyeonSeung Yu , KyeoReh Lee , YongKeun Park

Recently, novel imaging techniques based on the 'memory-effect' speckle-correlations have enabled diffraction-limited imaging through scattering layers and around corners. These techniques, however, are currently limited to imaging only…

Optics · Physics 2018-11-14 Ofer Salhov , Gil Weinberg , Ori Katz

The scattering of surface plasmons polaritons by a one-dimensional defect of the surface is theoretically studied, by means of both Rayleigh and modal expansions. The considered defects are either relief perturbations or variations in the…

Other Condensed Matter · Physics 2007-05-23 A. Yu. Nikitin , F. Lopez-Tejeira , L. Martin-Moreno

Despite significant advances in particle imaging technologies over the past two decades, few advances have been made in particle tracking, i.e. linking individual particle positions across time series data. The state-of-the-art tracking…

Soft Condensed Matter · Physics 2022-01-25 Ella M. King , Zizhao Wang , David A. Weitz , Frans Spaepen , Michael P. Brenner
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