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This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were…

The MR-Linac can enable real-time radiotherapy adaptation. However, real-time image acquisition is restricted to 2D to obtain sufficient spatial resolution, hindering accurate 3D segmentation. By reducing spatial resolution fast 3D imaging…

Medical Physics · Physics 2023-10-18 Samuel Fransson , David Tilly , Robin Strand

Image registration is an important tool for medical image analysis and is used to bring images into the same reference frame by warping the coordinate field of one image, such that some similarity measure is minimized. We study similarity…

Computer Vision and Pattern Recognition · Computer Science 2015-03-20 Sune Darkner , Jon Sporring

The diagnosis of prostate cancer faces a problem with overdiagnosis that leads to damaging side effects due to unnecessary treatment. Research has shown that the use of multi-parametric magnetic resonance images to conduct biopsies can…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Pedro C. Neto

Medical image segmentation is a relevant task as it serves as the first step for several diagnosis processes, thus it is indispensable in clinical usage. Whilst major success has been reported using supervised techniques, they assume a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Lihao Liu , Angelica I Aviles-Rivero , Carola-Bibiane Schönlieb

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

We propose an accurate and fast classification network for classification of brain tumors in MRI images that outperforms all lightweight methods investigated in terms of accuracy. We test our model on a challenging 2D T1-weighted CE-MRI…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Grace Billingsley , Julia Dietlmeier , Vivek Narayanaswamy , Andreas Spanias , Noel E. OConnor

Deep Learning-based 2D/3D registration methods are highly robust but often lack the necessary registration accuracy for clinical application. A refinement step using the classical optimization-based 2D/3D registration method applied in…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Srikrishna Jaganathan , Jian Wang , Anja Borsdorf , Karthik Shetty , Andreas Maier

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Many applications in image-guided surgery and therapy require fast and reliable non-linear, multi-modal image registration. Recently proposed unsupervised deep learning-based registration methods have demonstrated superior performance…

Image and Video Processing · Electrical Eng. & Systems 2022-10-07 Gerard Snaauw , Michele Sasdelli , Gabriel Maicas , Stephan Lau , Johan Verjans , Mark Jenkinson , Gustavo Carneiro

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression toward earlier and better patient-specific pathology management. However, conventional approaches rarely take advantage of…

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

Machine Learning · Computer Science 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek

Image segmentation is a crucial but challenging task that has many applications. In medical imaging for instance, intensity inhomogeneity and noise are common. In thigh muscle images, different muscles are closed packed together and there…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Haifeng Li , Weihong Guo , Jun Liu , Li Cui , Dongxing Xie

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin

We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Kathleen M. Lewis , Natalia S. Rost , John Guttag , Adrian V. Dalca

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have…

Longitudinal image registration is challenging and has not yet benefited from major performance improvements thanks to deep-learning. Inspired by Deep Image Prior, this paper introduces a different use of deep architectures as regularizers…

Medical image registration is an important task in automated analysis of multi-modal images and temporal data involving multiple patient visits. Conventional approaches, although useful for different image types, are time consuming. Of…

Image and Video Processing · Electrical Eng. & Systems 2020-03-30 Dwarikanath Mahapatra
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