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Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic…

Computation and Language · Computer Science 2026-04-09 Feng Chen , Manas Bedmutha , Janice Sabin , Andrea Hartzler , Nadir Weibel , Trevor Cohen

Static tools like the Patient Health Questionnaire-9 (PHQ-9) effectively screen depression but lack interactivity and adaptability. We developed HopeBot, a chatbot powered by a large language model (LLM) that administers the PHQ-9 using…

Artificial Intelligence · Computer Science 2026-01-15 Zhijun Guo , Alvina Lai , Julia Ive , Alexandru Petcu , Yutong Wang , Luyuan Qi , Johan H Thygesen , Kezhi Li

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Mental health resources available via websites and mobile apps provide support such as advice, journaling, and elements from cognitive behavioral therapy. The proliferation of spoken conversational agents, such as Alexa, Siri, and Google…

Human-Computer Interaction · Computer Science 2020-08-11 Juan C. Quiroz , Tristan Bongolan , Kiran Ijaz

Depression is a major contributor to the mental-health burden in Nigeria, yet screening coverage remains limited due to low access to clinicians, stigma, and language barriers. Traditional tools like the Patient Health Questionnaire-9…

Depression has proven to be a significant public health issue, profoundly affecting the psychological well-being of individuals. If it remains undiagnosed, depression can lead to severe health issues, which can manifest physically and even…

Human-Computer Interaction · Computer Science 2024-12-03 Chayan Tank , Sarthak Pol , Vinayak Katoch , Shaina Mehta , Avinash Anand , Rajiv Ratn Shah

With the rise of social media, millions of people are routinely expressing their moods, feelings, and daily struggles with mental health issues on social media platforms like Twitter. Unlike traditional observational cohort studies…

Depression is a global health concern with a critical need for increased patient screening. Speech technology offers advantages for remote screening but must perform robustly across patients. We have described two deep learning models…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Y. Lu , A. Harati , T. Rutowski , R. Oliveira , P. Chlebek , E. Shriberg

Digital screening and monitoring applications can aid providers in the management of behavioral health conditions. We explore deep language models for detecting depression, anxiety, and their co-occurrence from conversational speech…

Computation and Language · Computer Science 2024-12-31 Tomasz Rutowski , Elizabeth Shriberg , Amir Harati , Yang Lu , Piotr Chlebek , Ricardo Oliveira

Telehealth is a valuable tool for primary health care (PHC), where depression is a common condition. PHC is the first point of contact for most people with depression, but about 25% of diagnoses made by PHC physicians are inaccurate. Many…

Automated methods have been widely used to identify and analyze mental health conditions (e.g., depression) from various sources of information, including social media. Yet, deployment of such models in real-world healthcare applications…

Computation and Language · Computer Science 2022-04-25 Thong Nguyen , Andrew Yates , Ayah Zirikly , Bart Desmet , Arman Cohan

Mental health disorders remain among the leading cause of disability worldwide, yet conditions such as depression, anxiety, and Post-Traumatic Stress Disorder (PTSD) are frequently underdiagnosed or misdiagnosed due to subjective…

Computation and Language · Computer Science 2025-10-17 Jianfeng Zhu , Julina Maharjan , Xinyu Li , Karin G. Coifman , Ruoming Jin

In this work we propose a machine learning model for depression detection from transcribed clinical interviews. Depression is a mental disorder that impacts not only the subject's mood but also the use of language. To this end we use a…

Computation and Language · Computer Science 2020-06-16 D. Xezonaki , G. Paraskevopoulos , A. Potamianos , S. Narayanan

In psychological practices, standardized questionnaires serve as essential tools for assessing mental health through structured, clinically-validated questions (i.e., items). While social media platforms offer rich data for mental health…

Computation and Language · Computer Science 2025-06-03 Federico Ravenda , Seyed Ali Bahrainian , Andrea Raballo , Antonietta Mira , Noriko Kando

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

Perinatal depression (PND) affects 1 in 5 mothers, with 85% lacking support. Digital health tools offer early identification and prevention, potentially reducing PND risk by over 50% and improving engagement. Despite high interest, user…

Quantitative Methods · Quantitative Biology 2025-05-13 Rachel L. Wiley , Jim Schwoebel , Joel Shor , Bindu Chanagala , Matias Caccia , Adolfo M. García , Sheehan D. Fisher , Martin G. Frasch

Speech-based algorithms have gained interest for the management of behavioral health conditions such as depression. We explore a speech-based transfer learning approach that uses a lightweight encoder and that transfers only the encoder…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Amir Harati , Elizabeth Shriberg , Tomasz Rutowski , Piotr Chlebek , Yang Lu , Ricardo Oliveira

This study investigates the utility of speech signals for AI-based depression screening across varied interaction scenarios, including psychiatric interviews, chatbot conversations, and text readings. Participants include depressed patients…

Sound · Computer Science 2024-06-13 Yangbin Chen , Chenyang Xu , Chunfeng Liang , Yanbao Tao , Chuan Shi

This paper proposes a new depression detection system based on LLMs that is both interpretable and interactive. It not only provides a diagnosis, but also diagnostic evidence and personalized recommendations based on natural language…

Computation and Language · Computer Science 2023-05-10 Wei Qin , Zetong Chen , Lei Wang , Yunshi Lan , Weijieying Ren , Richang Hong

Recent research leverages large language models (LLMs) for early mental health detection, such as depression, often optimized with machine-generated data. However, their detection may be subject to unknown weaknesses. Meanwhile, quality…

Computation and Language · Computer Science 2025-05-26 Zongru Shao , Xin Wang , Zhanyang Liu , Chenhan Wang , K. P. Subbalakshmi
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