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Agents trained with deep reinforcement learning algorithms are capable of performing highly complex tasks including locomotion in continuous environments. We investigate transferring the learning acquired in one task to a set of previously…

Machine Learning · Computer Science 2024-03-06 Suzan Ece Ada , Emre Ugur , H. Levent Akin

In machine learning and molecular design, there exist two approaches: discriminative and generative. In the discriminative approach dubbed forward design, the goal is to map a set of features/molecules to their respective electronics…

Chemical Physics · Physics 2019-04-24 Alain Tchagang , Julio Valdés

Computer-aided design of molecules has the potential to disrupt the field of drug and material discovery. Machine learning, and deep learning, in particular, have been topics where the field has been developing at a rapid pace.…

Machine Learning · Computer Science 2022-08-08 Luca A. Thiede , Mario Krenn , AkshatKumar Nigam , Alan Aspuru-Guzik

Optimizing techniques for discovering molecular structures with desired properties is crucial in artificial intelligence(AI)-based drug discovery. Combining deep generative models with reinforcement learning has emerged as an effective…

Machine Learning · Computer Science 2024-04-01 Jinyeong Park , Jaegyoon Ahn , Jonghwan Choi , Jibum Kim

Designing composite materials as per the application requirements is fundamentally a challenging and time consuming task. Here we report the development of a deep neural network based computational framework capable of solving the forward…

Materials Science · Physics 2022-09-14 Ashank , Soumen Chakravarty , Pranshu Garg , Ankit Kumar , Manish Agrawal , Prabhat K. Agnihotri

In recent years, deep learning has made remarkable strides, surpassing human capabilities in tasks like strategy games, and it has found applications in complex domains, including protein folding. In the realm of quantum chemistry, machine…

Chemical Physics · Physics 2024-01-09 Rhyan Barrett , Julia Westermayr

From higher computational efficiency to enabling the discovery of novel and complex structures, deep learning has emerged as a powerful framework for the design and optimization of nanophotonic circuits and components. However, both…

Machine Learning · Computer Science 2022-09-13 Christopher Yeung , Benjamin Pham , Zihan Zhang , Katherine T. Fountaine , Aaswath P. Raman

The problem of Learning from Demonstration is targeted at learning to perform tasks based on observed examples. One approach to Learning from Demonstration is Inverse Reinforcement Learning, in which actions are observed to infer rewards.…

Neural and Evolutionary Computing · Computer Science 2016-08-11 Karan K. Budhraja , Tim Oates

Discovering novel stable molecules without training data remains a grand scientific challenge. Current molecular generative models are trained on large, pre-curated datasets, which introduce biases and limit exploration of novel chemistry.…

Machine Learning · Computer Science 2026-05-28 Bjarke Hastrup , Francois Cornet , Tejs Vegge , Arghya Bhowmik

Generating novel graph structures that optimize given objectives while obeying some given underlying rules is fundamental for chemistry, biology and social science research. This is especially important in the task of molecular graph…

Machine Learning · Computer Science 2019-02-26 Jiaxuan You , Bowen Liu , Rex Ying , Vijay Pande , Jure Leskovec

Understanding how nano- or micro-scale structures and material properties can be optimally configured to attain specific functionalities remains a fundamental challenge. Photonic metasurfaces, for instance, can be spectrally tuned through…

The goal of most materials discovery is to discover materials that are superior to those currently known. Fundamentally, this is close to extrapolation, which is a weak point for most machine learning models that learn the probability…

Biomolecules · Quantitative Biology 2024-05-08 Hyunseung Kim , Haeyeon Choi , Dongju Kang , Won Bo Lee , Jonggeol Na

In electromagnetic inverse scattering, the goal is to reconstruct object permittivity using scattered waves. While deep learning has shown promise as an alternative to iterative solvers, it is primarily used in supervised frameworks which…

Searching through chemical space is an exceptionally challenging problem because the number of possible molecules grows combinatorially with the number of atoms. Large, autoregressive models trained on databases of chemical compounds have…

Machine Learning · Computer Science 2025-10-24 Shriram Chennakesavalu , Frank Hu , Sebastian Ibarraran , Grant M. Rotskoff

Transfer learning, in which a network is trained on one task and re-purposed on another, is often used to produce neural network classifiers when data is scarce or full-scale training is too costly. When the goal is to produce a model that…

Machine Learning · Computer Science 2020-02-24 Ali Shafahi , Parsa Saadatpanah , Chen Zhu , Amin Ghiasi , Christoph Studer , David Jacobs , Tom Goldstein

This work provides a Deep Reinforcement Learning approach to solving a periodic review inventory control system with stochastic vendor lead times, lost sales, correlated demand, and price matching. While this dynamic program has…

Machine Learning · Computer Science 2022-11-30 Dhruv Madeka , Kari Torkkola , Carson Eisenach , Anna Luo , Dean P. Foster , Sham M. Kakade

In inverse reinforcement learning (IRL), an agent seeks to replicate expert demonstrations through interactions with the environment. Traditionally, IRL is treated as an adversarial game, where an adversary searches over reward models, and…

Machine Learning · Computer Science 2025-04-23 Arnav Kumar Jain , Harley Wiltzer , Jesse Farebrother , Irina Rish , Glen Berseth , Sanjiban Choudhury

While deep neural networks have achieved remarkable success in various computer vision tasks, they often fail to generalize to new domains and subtle variations of input images. Several defenses have been proposed to improve the robustness…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Omid Poursaeed , Tianxing Jiang , Harry Yang , Serge Belongie , SerNam Lim

Being able to reason in an environment with a large number of discrete actions is essential to bringing reinforcement learning to a larger class of problems. Recommender systems, industrial plants and language models are only some of the…

When deploying artificial agents in real-world environments where they interact with humans, it is crucial that their behavior is aligned with the values, social norms or other requirements of that environment. However, many environments…

Machine Learning · Computer Science 2023-05-05 Mattijs Baert , Pietro Mazzaglia , Sam Leroux , Pieter Simoens