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In the past years, deep learning models have been successfully applied in several cognitive tasks. Originally inspired by neuroscience, these models are specific examples of differentiable programs. In this paper we define and motivate…

Machine Learning · Computer Science 2022-05-17 Adrián Hernández , Gilles Millerioux , José M. Amigó

We tackle the problem of protein secondary structure prediction using a common task framework. This lead to the introduction of multiple ideas for neural architectures based on state of the art building blocks, used in this task for the…

Determining the aqueous solubility of molecules is a vital step in many pharmaceutical, environmental, and energy storage applications. Despite efforts made over decades, there are still challenges associated with developing a solubility…

Materials Science · Physics 2022-09-05 Gihan Panapitiya , Michael Girard , Aaron Hollas , Vijay Murugesan , Wei Wang , Emily Saldanha

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Characterizing structural and dynamic properties of proteins and large macromolecular assemblies is crucial to understand the molecular mechanisms underlying biological functions. In the field of Structural Biology, no single method…

Quantitative Methods · Quantitative Biology 2023-10-04 Samuel Hoff , Maximilian Zinke , Nadia Izadi-Pruneyre , Massimiliano Bonomi

Deep learning models for medical data are typically trained using task specific objectives that encourage representations to collapse onto a small number of discriminative directions. While effective for individual prediction problems, this…

Machine Learning · Computer Science 2026-02-10 Yuanyun Zhang , Mingxuan Zhang , Siyuan Li , Zihan Wang , Haoran Chen , Wenbo Zhou , Shi Li

We propose to solve a label ranking problem as a structured output regression task. We adopt a least square surrogate loss approach that solves a supervised learning problem in two steps: the regression step in a well-chosen feature space…

Machine Learning · Statistics 2018-07-09 Anna Korba , Alexandre Garcia , Florence d'Alché Buc

Representation learning, and interpreting learned representations, are key areas of focus in machine learning and neuroscience. Both fields generally use representations as a means to understand or improve a system's computations. In this…

Machine Learning · Computer Science 2024-09-24 Andrew Kyle Lampinen , Stephanie C. Y. Chan , Katherine Hermann

With this paper, we contribute to the growing research area of feature-based analysis of bio-inspired computing. In this research area, problem instances are classified according to different features of the underlying problem in terms of…

Neural and Evolutionary Computing · Computer Science 2016-02-10 Shayan Poursoltan , Frank Neumann

In this paper we propose the Structured Deep Neural Network (Structured DNN) as a structured and deep learning algorithm, learning to find the best structured object (such as a label sequence) given a structured input (such as a vector…

Machine Learning · Computer Science 2015-06-04 Yi-Hsiu Liao , Hung-Yi Lee , Lin-shan Lee

One of the long-standing problems in materials science is how to predict a material's structure and then its properties given only its composition. Experimental characterization of crystal structures has been widely used for structure…

Materials Science · Physics 2022-03-29 Rongzhi Dong , Yong Zhao , Yuqi Song , Nihang Fu , Sadman Sadeed Omee , Sourin Dey , Qinyang Li , Lai Wei , Jianjun Hu

While invaluable for many computer vision applications, decomposing a natural image into intrinsic reflectance and shading layers represents a challenging, underdetermined inverse problem. As opposed to strict reliance on conventional…

Computer Vision and Pattern Recognition · Computer Science 2018-09-03 Qingnan Fan , Jiaolong Yang , Gang Hua , Baoquan Chen , David Wipf

Deep learning has attracted great attention recently and yielded the state of the art performance in dimension reduction and classification problems. However, it cannot effectively handle the structured output prediction, e.g. sequential…

Machine Learning · Computer Science 2015-05-05 Gang Chen , Ran Xu , Sargur Srihari

Supervised learning is ubiquitous in medical image analysis. In this paper we consider the problem of meta-learning -- predicting which methods will perform well in an unseen classification problem, given previous experience with other…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Veronika Cheplygina , Pim Moeskops , Mitko Veta , Behdad Dasht Bozorg , Josien Pluim

Inspired by a new coded computation algorithm for invertible functions, we propose Coded-InvNet a new approach to design resilient prediction serving systems that can gracefully handle stragglers or node failures. Coded-InvNet leverages…

Machine Learning · Computer Science 2021-06-28 Tuan Dinh , Kangwook Lee

We present an exploration of machine learning architectures for predicting brain responses to realistic images on occasion of the Algonauts Challenge 2023. Our research involved extensive experimentation with various pretrained models.…

Neurons and Cognition · Quantitative Biology 2023-09-20 Riccardo Chimisso , Sathya Buršić , Paolo Marocco , Giuseppe Vizzari , Dimitri Ognibene

Predicting drug side-effects before they occur is a key task in keeping the number of drug-related hospitalizations low and to improve drug discovery processes. Automatic predictors of side-effects generally are not able to process the…

Machine Learning · Statistics 2022-12-01 Pietro Bongini , Elisa Messori , Niccolò Pancino , Monica Bianchini

Designing and generating new data under targeted properties has been attracting various critical applications such as molecule design, image editing and speech synthesis. Traditional hand-crafted approaches heavily rely on expertise…

Machine Learning · Computer Science 2024-03-19 Shiyu Wang , Yuanqi Du , Xiaojie Guo , Bo Pan , Zhaohui Qin , Liang Zhao

Motivation: Traditional computational cluster schedulers are based on user inputs and run time needs request for memory and CPU, not IO. Heavily IO bound task run times, like ones seen in many big data and bioinformatics problems, are…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-27 Christopher Harrison , Christine R. Kirkpatrick , Inês Dutra

Artificial intelligence has provided us with an exploration of a whole new research era. As more data and better computational power become available, the approach is being implemented in various fields. The demand for it in health…

Machine Learning · Computer Science 2020-08-11 Gloria Hyunjung Kwak , Pan Hui