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Clustering is a fundamental unsupervised representation learning task with wide application in computer vision and pattern recognition. Deep clustering utilizes deep neural networks to learn latent representation, which is suitable for…
The clustering of data into physically meaningful subsets often requires assumptions regarding the number, size, or shape of the subgroups. Here, we present a new method, simultaneous coherent structure coloring (sCSC), which accomplishes…
Given multi-type point maps from different place-types (e.g., tumor regions), our objective is to develop a classifier trained on the source place-type to accurately distinguish between two classes of the target place-type based on their…
Classical approaches in cluster analysis are typically based on a feature space analysis. However, many applications lead to datasets with additional spatial information and a ground truth with spatially coherent classes, which will not…
Modern clustering approaches often trade interpretability for performance, particularly in deep learning-based methods. We present Generative Kernel Spectral Clustering (GenKSC), a novel model combining kernel spectral clustering with…
The application of machine learning to radiological images is an increasingly active research area that is expected to grow in the next five to ten years. Recent advances in machine learning have the potential to recognize and classify…
Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…
Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…
In today's data-driven digital era, the amount as well as complexity, such as multi-view, non-Euclidean, and multi-relational, of the collected data are growing exponentially or even faster. Clustering, which unsupervisely extracts valid…
Identifying new disease-related patterns in medical imaging data with the help of machine learning enlarges the vocabulary of recognizable findings. This supports diagnostic and prognostic assessment. However, image appearance varies not…
Clustering of hyperspectral images is a fundamental but challenging task. The recent development of hyperspectral image clustering has evolved from shallow models to deep and achieved promising results in many benchmark datasets. However,…
Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients. This paper describes a development in improving the learning-based registration algorithms, for this challenging…
Subspace clustering assumes that the data is sepa-rable into separate subspaces. Such a simple as-sumption, does not always hold. We assume that, even if the raw data is not separable into subspac-es, one can learn a representation…
Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…
Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…
Clustering, as an unsupervised technique, plays a pivotal role in various data analysis applications. Among clustering algorithms, Spectral Clustering on Euclidean Spaces has been extensively studied. However, with the rapid evolution of…
We train three convolutional neural networks (CNNs) to classify galaxies with Galaxy Zoo 2 dataset and extract the activations from the last fully connected layer or the last average pooling layer of CNNs to study the high-dimensional…
Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…
Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…
Background: Current research suggests that a small set of "driver" mutations are responsible for tumorigenesis while a larger body of "passenger" mutations occurs in the tumor but does not progress the disease. Due to recent pharmacological…