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The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

Parameter estimation in diffusion processes from discrete observations up to a first-hitting time is clearly of practical relevance, but does not seem to have been studied so far. In neuroscience, many models for the membrane potential…

Probability · Mathematics 2014-03-06 Enrico Bibbona , Susanne Ditlevsen

We introduce estimation and test procedures through divergence minimization for models satisfying linear constraints with unknown parameter. Several statistical examples and motivations are given. These procedures extend the empirical…

Statistics Theory · Mathematics 2008-11-24 Michel Broniatowski , Amor Keziou

Configurational entropy has been revealed as a reliable method for constraining some parameters of a given model [Phys. Rev. D \textbf{92} (2015) 126005, Eur. Phys. J. C \textbf{76} (2016) 100]. In this letter we calculate the…

High Energy Physics - Theory · Physics 2016-10-12 R. A. C. Correa , P. H. R. S. Moraes , A. de Souza Dutra , W. de Paula , T. Frederico

We propose a new procedure for inference on optimal treatment regimes in the model-free setting, which does not require to specify an outcome regression model. Existing model-free estimators for optimal treatment regimes are usually not…

Methodology · Statistics 2020-07-06 Yunan Wu , Lan Wang

We propose a method for inferring \emph{parameterized regular types} for logic programs as solutions for systems of constraints over sets of finite ground Herbrand terms (set constraint systems). Such parameterized regular types generalize…

Logic in Computer Science · Computer Science 2010-02-16 F. Bueno , J. Navas , M. Hermenegildo

Mechanistic mathematical models of biological systems usually contain a number of unknown parameters whose values need to be estimated from available experimental data in order for the models to be validated and used to make quantitative…

Quantitative Methods · Quantitative Biology 2025-06-16 Yue Liu , Philip K. Maini , Ruth E. Baker

This paper presents a study of the large-sample behavior of the posterior distribution of a structural parameter which is partially identified by moment inequalities. The posterior density is derived based on the limited information…

Statistics Theory · Mathematics 2010-01-13 Yuan Liao , Wenxin Jiang

Prescriptive process monitoring is a family of techniques to optimize the performance of a business process by triggering interventions at runtime. Existing prescriptive process monitoring techniques assume that the number of interventions…

Machine Learning · Computer Science 2021-10-12 Mahmoud Shoush , Marlon Dumas

We develop, discuss, and compare several inference techniques to constrain theory parameters in collider experiments. By harnessing the latent-space structure of particle physics processes, we extract extra information from the simulator.…

High Energy Physics - Phenomenology · Physics 2018-09-19 Johann Brehmer , Kyle Cranmer , Gilles Louppe , Juan Pavez

We develop new methods to integrate experimental and observational data in causal inference. While randomized controlled trials offer strong internal validity, they are often costly and therefore limited in sample size. Observational data,…

Econometrics · Economics 2025-11-04 Xuelin Yang , Licong Lin , Susan Athey , Michael I. Jordan , Guido W. Imbens

In this paper, we develop uniform inference methods for the conditional mode based on quantile regression. Specifically, we propose to estimate the conditional mode by minimizing the derivative of the estimated conditional quantile function…

Statistics Theory · Mathematics 2021-04-14 Tao Zhang , Kengo Kato , David Ruppert

Hierarchical models allow for heterogeneous behaviours in a population while simultaneously borrowing estimation strength across all subpopulations. Unfortunately, existing likelihood-based methods for fitting hierarchical models have high…

Methodology · Statistics 2015-12-16 Patrick O. Perry

We present a general methodology for performing statistical inference on the components of a real-valued matrix parameter for which rows and columns are subject to order restrictions. The proposed estimation procedure is based on an…

Statistics Theory · Mathematics 2008-12-18 Eric Teoh , Abraham Nyska , Uri Wormser , Shyamal D. Peddada

This paper develops maximum score estimation of preference parameters in the binary choice model under uncertainty in which the decision rule is affected by conditional expectations. The preference parameters are estimated in two stages: we…

Methodology · Statistics 2013-12-03 Le-Yu Chen , Sokbae Lee , Myung Jae Sung

We extend the constrained maximum likelihood estimation theory for parameters of a completely identified model, proposed by Aitchison and Silvey (1958), to parameters arising from a partially identified model. With a partially identified…

Statistics Theory · Mathematics 2016-08-01 Hao Luo , Alexandre Bouchard-Côté , Gabriela Cohen Freue , Paul Gustafson

We present a new fitting technique based on the parametric bootstrap method, which relies on the idea to produce artificial measurements using the estimated probability distribution of the experimental data. In order to investigate the main…

Data Analysis, Statistics and Probability · Physics 2020-03-18 Paolo Pedroni , Stefano Sconfietti

Prediction-powered inference (PPI) is a method that improves statistical estimates based on limited human-labeled data. Specifically, PPI methods provide tighter confidence intervals by combining small amounts of human-labeled data with…

Machine Learning · Computer Science 2024-05-13 R. Alex Hofer , Joshua Maynez , Bhuwan Dhingra , Adam Fisch , Amir Globerson , William W. Cohen

Moment restrictions and their conditional counterparts emerge in many areas of machine learning and statistics ranging from causal inference to reinforcement learning. Estimators for these tasks, generally called methods of moments, include…

Machine Learning · Computer Science 2023-06-14 Heiner Kremer , Yassine Nemmour , Bernhard Schölkopf , Jia-Jie Zhu

The Fisher information matrix (FIM) plays an important role in the analysis of parameter inference and system design problems. In a number of cases, however, the statistical data distribution and its associated information matrix are either…

Statistics Theory · Mathematics 2016-11-24 Dave Zachariah , Petre Stoica