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We propose a set of kernel-based tools to evaluate the designs and tune the hyperparameters of conditional sequence models, with a focus on problems in computational biology. The backbone of our tools is a new measure of discrepancy between…

Machine Learning · Statistics 2025-10-20 Pierre Glaser , Steffanie Paul , Alissa M. Hummer , Charlotte M. Deane , Debora S. Marks , Alan N. Amin

To detect differences between the mean curves of two samples in longitudinal study or functional data analysis, we usually need to partition the temporal or spatial domain into several pre-determined sub-areas. In this paper we apply the…

Methodology · Statistics 2015-05-01 Peirong Xu , Youngjo Lee , Jian Qing Shi

Conditional Maximum Mean Discrepancy (CMMD) can capture the discrepancy between conditional distributions by drawing support from nonlinear kernel functions, thus it has been successfully used for pattern classification. However, CMMD does…

Computer Vision and Pattern Recognition · Computer Science 2020-08-25 Chuan-Xian Ren , Pengfei Ge , Dao-Qing Dai , Hong Yan

Approximate Markov chain Monte Carlo (MCMC) offers the promise of more rapid sampling at the cost of more biased inference. Since standard MCMC diagnostics fail to detect these biases, researchers have developed computable Stein discrepancy…

Machine Learning · Statistics 2020-10-16 Jackson Gorham , Lester Mackey

This paper is about two related decision theoretic problems, nonparametric two-sample testing and independence testing. There is a belief that two recently proposed solutions, based on kernels and distances between pairs of points, behave…

Machine Learning · Statistics 2014-11-25 Sashank J. Reddi , Aaditya Ramdas , Barnabás Póczos , Aarti Singh , Larry Wasserman

Statistical depth functions provide measures of the outlyingness, or centrality, of the elements of a space with respect to a distribution. It is a nonparametric concept applicable to spaces of any dimension, for instance, multivariate and…

Statistics Theory · Mathematics 2024-07-31 Felix Gnettner , Claudia Kirch , Alicia Nieto-Reyes

Hypothesis testing in high dimensional data is a notoriously difficult problem without direct access to competing models' likelihood functions. This paper argues that statistical divergences can be used to quantify the difference between…

Data Analysis, Statistics and Probability · Physics 2024-08-02 Jeremy J. H. Wilkinson , Christopher G. Lester

Given two sets of independent samples from unknown distributions $P$ and $Q$, a two-sample test decides whether to reject the null hypothesis that $P=Q$. Recent attention has focused on kernel two-sample tests as the test statistics are…

Machine Learning · Statistics 2018-05-22 Shengyu Zhu , Biao Chen , Zhitang Chen

This paper develops tests for inequality constraints of nonparametric regression functions. The test statistics involve a one-sided version of $L_p$-type functionals of kernel estimators $(1 \leq p < \infty)$. Drawing on the approach of…

Statistics Theory · Mathematics 2023-08-28 Sokbae Lee , Kyungchul Song , Yoon-Jae Whang

We construct and analyze a neural network two-sample test to determine whether two datasets came from the same distribution (null hypothesis) or not (alternative hypothesis). We perform time-analysis on a neural tangent kernel (NTK)…

Machine Learning · Statistics 2024-07-11 Varun Khurana , Xiuyuan Cheng , Alexander Cloninger

We consider training a deep neural network to generate samples from an unknown distribution given i.i.d. data. We frame learning as an optimization minimizing a two-sample test statistic---informally speaking, a good generator network…

Machine Learning · Statistics 2015-05-18 Gintare Karolina Dziugaite , Daniel M. Roy , Zoubin Ghahramani

We introduce a kernel-based goodness-of-fit test for censored data, where observations may be missing in random time intervals: a common occurrence in clinical trials and industrial life-testing. The test statistic is straightforward to…

Methodology · Statistics 2018-10-11 Tamara Fernández , Arthur Gretton

Distance-based tests, also called "energy statistics", are leading methods for two-sample and independence tests from the statistics community. Kernel-based tests, developed from "kernel mean embeddings", are leading methods for two-sample…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Joshua T. Vogelstein

This paper adresses the problem of testing for the equality of $k$ probability distributions on Hilbert spaces, with $k\geqslant 2$. We introduce a generalization of the maximum variance discrepancy called multiple maximum variance…

Statistics Theory · Mathematics 2024-04-16 Armando Sosthène Kali Balogoun , Guy Martial Nkiet

This study presents an efficient approach for incomplete data classification, where the entries of samples are missing or masked due to privacy preservation. To deal with these incomplete data, a new kernel function with asymmetric…

Machine Learning · Computer Science 2016-11-22 Bo-Wei Chen

Detecting the emergence of abrupt property changes in time series is a challenging problem. Kernel two-sample test has been studied for this task which makes fewer assumptions on the distributions than traditional parametric approaches.…

Machine Learning · Statistics 2019-01-21 Wei-Cheng Chang , Chun-Liang Li , Yiming Yang , Barnabás Póczos

Considering a regression model, we address the question of testing the nullity of the regression function. The testing procedure is available when the variance of the observations is unknown and does not depend on any prior information on…

Statistics Theory · Mathematics 2019-04-08 Thi Thien Trang Bui

This paper introduces an approach for detecting differences in the first-order structures of spatial point patterns. The proposed approach leverages the kernel mean embedding in a novel way by introducing its approximate version tailored to…

Methodology · Statistics 2020-06-15 Raif M. Rustamov , James T. Klosowski

We propose a novel kernel-based nonparametric two-sample test, employing the combined use of kernel mean and kernel covariance embedding. Our test builds on recent results showing how such combined embeddings map distinct probability…

Machine Learning · Statistics 2025-09-16 Leonardo V. Santoro , Victor M. Panaretos

Independence testing plays a central role in statistical and causal inference from observational data. Standard independence tests assume that the data samples are independent and identically distributed (i.i.d.) but that assumption is…

Machine Learning · Statistics 2022-07-04 Ragib Ahsan , Zahra Fatemi , David Arbour , Elena Zheleva
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