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Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedicated…

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

In this paper we present a mathematical and numerical framework for a procedure of imaging anisotropic electrical conductivity tensor by integrating magneto-acoutic tomography with data acquired from diffusion tensor imaging.…

Numerical Analysis · Mathematics 2017-11-22 Habib Ammari , Lingyun Qiu , Fadil Santosa , Wenlong Zhang

Catheter ablation has limited therapeutic efficacy against non-paroxysmal atrial fibrillation (AF), and electrophysiological studies using mapping catheters have been applied to evaluate the AF substrate. However, many of these approaches…

Signal Processing · Electrical Eng. & Systems 2024-08-08 Hiroshi Seno , Toshiya Kojima , Masatoshi Yamazaki , Ichiro Sakuma , Katsuhito Fujiu , Naoki Tomii

Echocardiography is the most commonly used imaging technique in clinical cardiology. Due to the high demand for this type of examination and the small number of specialists, there is a need to support the examination process through…

Proteins move and deform to ensure their biological functions. Despite significant progress in protein structure prediction, approximating conformational ensembles at physiological conditions remains a fundamental open problem. This paper…

Biomolecules · Quantitative Biology 2025-04-07 Valentin Lombard , Sergei Grudinin , Elodie Laine

Mechanical and phononic metamaterials exhibiting negative elastic moduli, gapped vibrational spectra, or topologically protected modes enable precise control of structural and acoustic functionalities. While much progress has been made in…

Materials Science · Physics 2019-09-25 Henrik Ronellenfitsch , Norbert Stoop , Josephine Yu , Aden Forrow , Jörn Dunkel

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

We propose and test stable algorithms for the reconstruction of the internal conductivity of a biological object using acousto-electric measurements. Namely, the conventional impedance tomography scheme is supplemented by scanning the…

Analysis of PDEs · Mathematics 2015-05-20 Peter Kuchment , Leonid Kunyansky

Developing a bottom-up (molecular) theory for the electromechanical response of aperiodic materials is a prerequisite for understanding the piezoelectric properties of systems such as nanoparticles, (non-crystalline) polymers, or…

Chemical Physics · Physics 2017-07-25 Keith A. Werling , Geoffrey R. Hutchison , Daniel S. Lambrecht

Cardiac contraction is a rapid, coordinated process that unfolds across three-dimensional tissue on millisecond timescales. Traditional optical imaging is often inadequate for capturing dynamic cellular structure in the beating heart…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Yi Gong , Xinyuan Zhang , Jichen Chai , Yichen Ding , Yifei Lou

Electrical impedance tomography is an imaging modality for extracting information on the conductivity distribution inside a physical body from boundary measurements of current and voltage. In many practical applications, it is a priori…

Numerical Analysis · Mathematics 2014-06-06 Lauri Harhanen , Nuutti Hyvönen , Helle Majander , Stratos Staboulis

In this article, we consider the problem of finding the support of an inhomogenous possibly anisotropic inclusion in a background of constant electric conductivity from the electrical impedance tomography data at the boundary of a bounded…

Functional Analysis · Mathematics 2007-05-23 Erkki J. Somersalo

Invasive cardiac catheterisation is a common procedure that is carried out before surgical intervention. Yet, invasive cardiac diagnostics are full of risks, especially for young children. Decades of research has been conducted on the so…

Machine Learning · Computer Science 2018-02-08 Avinash Malik , Tommy Peng , Mark Trew

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Deep learning-based cardiac segmentation has seen significant advancements over the years. Many studies have tackled the challenge of anatomically incorrect segmentation predictions by introducing auxiliary modules. These modules either…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Zahid Ullah , Jihie Kim

We present a novel microscopic tridomain model describing the electrical activity in cardiac tissue with dynamical gap junctions. The microscopic tridomain system consists of three PDEs modeling the tissue electrical conduction in the…

Analysis of PDEs · Mathematics 2022-06-01 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

The capability to control the type and amount of charge carriers in a material and, in the extreme case, the transition from metal to insulator is one of the key challenges of modern electronics. By employing angle resolved photoemission…

Materials Science · Physics 2008-10-23 S. Y. Zhou , D. A. Siegel , A. V. Fedorov , A. Lanzara

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures…

Signal Processing · Electrical Eng. & Systems 2023-12-14 Matthew McDougall , Hezam Albaqami , Ghulam Mubashar Hassan , Amitava Datta