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Related papers: PET-enabled Dual-Energy CT: Image Reconstruction a…

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Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Quantitative image reconstruction in dual-energy computed tomography (CT) remains a topic of active research. We read with interest ``DIRECT-Net: A unified mutual-domain material decomposition network for quantitative dual-energy CT…

Medical Physics · Physics 2022-12-20 Xiaochuan Pan , Emil Y. Sidky

Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…

Medical Physics · Physics 2017-06-29 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Multispectral computed tomography (CT) enables advanced material characterization by acquiring energy-resolved projection data. However, since the incoming X-ray flux is be distributed across multiple narrow energy bins, the photon count…

Positron Emission Tomography / Computed Tomography (PET/CT) plays a critical role in medical imaging, combining functional and anatomical information to aid in accurate diagnosis. However, image quality degradation due to noise, compression…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Siqiao Li , Chen Hui , Wei Zhang , Rui Liang , Chenyue Song , Feng Jiang , Haiqi Zhu , Zhixuan Li , Hong Huang , Xiang Li

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

X-ray energy spectrum plays an essential role in imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of the spectrum estimation methods are indirect and are usually suffered from various limitations. The…

Medical Physics · Physics 2016-04-19 Wei Zhao , Qiude Zhang , Tianye Niu

X-ray computed tomography (CT) reconstructs cross-sectional images from projection data. However, ionizing X-ray radiation associated with CT scanning might induce cancer and genetic damage. Therefore, the reduction of radiation dose has…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Huidong Xie , Hongming Shan , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Snehashis Roy , John A. Butman , Dzung L. Pham

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Multi-energy CT takes advantage of the non-linearly varying attenuation properties of elemental media with respect to energy, enabling more precise material identification than single-energy CT. The increased precision comes with the cost…

Medical Physics · Physics 2020-02-14 Jussi Toivanen , Alexander Meaney , Samuli Siltanen , Ville Kolehmainen

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…

Medical Physics · Physics 2025-04-18 Junbo Peng , Tonghe Wang , Shaoyan Pan , Xiaofeng Yang

Acquiring high-quality Positron Emission Tomography (PET) images requires administering high-dose radiotracers, which increases radiation exposure risks. Generating standard-dose PET (SPET) from low-dose PET (LPET) has become a potential…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Xiaolong Niu , Zanting Ye , Xu Han , Yanchao Huang , Hao Sun , Hubing Wu , Lijun Lu

Positron Emission Mammography (PEM) imaging systems with the ability in detection of millimeter-sized tumors were developed in recent years. And some of them have been well used in clinical applications. In consideration of biopsy…

Medical Physics · Physics 2016-08-03 Xiao-Yue Gu , Wei Zhou , Lin Li , Peng-Fei Yin , Lei-Min Shang , Ming-Kai Yun , Zhen-Rui Lu , Xian-Chao Huang , Long Wei

Positron emission tomographs (PET) do not measure an image directly. Instead, they measure at the boundary of the field-of-view (FOV) of PET tomograph a sinogram that consists of measurements of the sums of all the counts along the lines…