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Flow networks are essential for both living organisms and enginneered systems. These networks often present complex dynamics controlled, at least in part, by their topology. Previous works have shown that topologically complex networks…

Soft Condensed Matter · Physics 2020-03-24 Miguel Ruiz-Garcia , Eleni Katifori

We present a systematic procedure for testing whether reaction networks exhibit non-expansivity or monotonicity. This procedure identifies explicit norms under which a network is non-expansive or cones for which the system is monotone-or…

Dynamical Systems · Mathematics 2025-01-28 Alon Duvall

In living cells, biochemical reactions are catalyzed by specific enzymes and connect to one another by sharing substrates and products, forming complex networks. In our previous studies, we established a framework determining the responses…

Molecular Networks · Quantitative Biology 2017-09-06 Takashi Okada , Atsushi Mochizuki

Stochastic reaction networks are mathematical models frequently used in, but not limited to, biochemistry. These models are continuous-time Markov chains whose transition rates depend on certain parameters called rate constants, which…

Probability · Mathematics 2025-08-14 Daniele Cappelletti , Aidan Howells , Chuang Xu

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

Chemical systems are interpreted through the species they contain and the reactions they may undergo, i.e., their chemical reaction network (CRN). In spite of their central importance to chemistry, the structure of CRNs continues to be…

Statistical Mechanics · Physics 2025-06-17 Alex Blokhuis , Martijn van Kuppeveld , Daan van de Weem , Robert Pollice

We identify the thermodynamic conditions necessary to observe indefinite growth in homogeneous open chemical reaction networks (CRNs) satisfying mass action kinetics. We also characterize the thermodynamic efficiency of growth by…

Molecular Networks · Quantitative Biology 2024-12-05 Shesha Gopal Marehalli Srinivas , Francesco Avanzini , Massimiliano Esposito

Biological networks have been recently found to exhibit many topological properties of the so-called complex networks. It has been reported that they are, in general, both highly skewed and directed. In this paper, we report on the dynamics…

Molecular Networks · Quantitative Biology 2007-05-23 Jesus Gomez-Gardenes , Yamir Moreno , Luis M. Floria

For many real physico-chemical complex systems detailed mechanism includes both reversible and irreversible reactions. Such systems are typical in homogeneous combustion and heterogeneous catalytic oxidation. Most complex enzyme reactions…

Statistical Mechanics · Physics 2013-01-17 A. N. Gorban , E. M. Mirkes , G. S. Yablonsky

The research concerns the dynamics of complex autonomous Kauffman networks. The article defines and shows using simulation experiments half-chaotic networks, which exhibit features much more similar to typically modeled systems like a…

Adaptation and Self-Organizing Systems · Physics 2022-01-14 Andrzej Gecow

Many reaction networks arising in applications are multistationary, that is, they have the capacity for more than one steady state; while some networks exhibit absolute concentration robustness (ACR), which means that some species…

Dynamical Systems · Mathematics 2024-11-20 Nidhi Kaihnsa , Tung Nguyen , Anne Shiu

Nonreciprocity, a hallmark of nonequilibrium systems, can generate dynamics not possible near thermodynamic equilibrium, including oscillatory and rotating patterns. The onset of temporal oscillations is often evident in linearized…

Statistical Mechanics · Physics 2026-04-21 Daniel Evans , Yizhi Shen , Ahmad K. Omar

The behavior of the network and its stability are governed by both dynamics of individual nodes as well as their topological interconnections. Attention mechanism as an integral part of neural network models was initially designed for…

Machine Learning · Computer Science 2022-12-20 Nooshin Bahador , Milad Lankarany

Autocatalytic chemical networks play a predominant role in a large number of natural systems such as in metabolic pathways and in ecological networks. Despite recent efforts, the precise impact of thermodynamic constraints on these networks…

Chemical Physics · Physics 2024-06-14 Armand Despons , Yannick de Decker , David Lacoste

We consider steady states of dynamics that have an underlying network structure. We study how a steady state responds to small perturbations in the network parameters and how this sensitivity is connected to the network structure. We…

Molecular Networks · Quantitative Biology 2023-03-20 Robin Chemnitz

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

Quantitative Methods · Quantitative Biology 2015-06-19 Christoph Zechner , Heinz Koeppl

Reaction networks are a general formalism for describing collections of classical entities interacting in a random way. While reaction networks are mainly studied by chemists, they are equivalent to Petri nets, which are used for similar…

Mathematical Physics · Physics 2021-11-23 John C. Baez

Autocatalytic chemical reaction networks can collectively replicate or maintain their constituents despite degradation reactions only above a certain threshold, which we refer to as the decay threshold. When the chemical network has a…

Molecular Networks · Quantitative Biology 2025-11-17 Armand Despons , Jérémie Unterberger , David Lacoste

We analyze the probability distribution for entropy production rates of trajectories evolving on a class of out-of-equilibrium kinetic networks. These networks can serve as simple models for driven dynamical systems, which are of particular…

Statistical Mechanics · Physics 2014-08-05 Suriyanarayanan Vaikuntanathan , Todd R. Gingrich , Phillip L. Geissler

In networks of nonlinear oscillators, symmetries place hard constraints on the system that can be exploited to predict universal dynamical features and steady-states, providing a rare generic organizing principle for far-from-equilibrium…

Pattern Formation and Solitons · Physics 2021-03-02 Ian Hunter , Michael M. Norton , Bolun Chen , Chris Simonetti , Maria Eleni Moustaka , Jonathan Touboul , Seth Fraden