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Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Objective:This study introduces a residual error-shifting mechanism that drastically reduces sampling steps while preserving critical anatomical details, thus accelerating MRI reconstruction. Approach:We propose a novel diffusion-based SR…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Mojtaba Safari , Shansong Wang , Zach Eidex , Qiang Li , Erik H. Middlebrooks , David S. Yu , Xiaofeng Yang

Most existing MRI reconstruction methods perform tar-geted reconstruction of the entire MR image without tak-ing specific tissue regions into consideration. This may fail to emphasize the reconstruction accuracy on im-portant tissues for…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Yu Guan , Chuanming Yu , Shiyu Lu , Zhuoxu Cui , Dong Liang , Qiegen Liu

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Fluctuation-enhanced sensing comprises the analysis of the stochastic component of the sensor signal and the utilization of the microscopic dynamics of the interaction between the agent and the sensor. We study the relationship between the…

Data Analysis, Statistics and Probability · Physics 2012-07-13 P. Makra , Z. Topalian , C. G. Granqvist , L. B. Kish , C. Kwan

Imaging in thick biological tissues is often degraded by sample-induced aberrations, which reduce image quality and resolution, particularly in super-resolution techniques. While hardware-based adaptive optics, which correct aberrations…

By integrating the generative strengths of diffusion models with the representation capabilities of frequency-domain attention, DFAM effectively enhances reconstruction performance under low-SNR condi-tions. Experimental results demonstrate…

Medical Physics · Physics 2025-07-25 Xin Xie , Yu Guan , Zhuoxu Cui , Dong Liang , Qiegen Liu

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

Optics · Physics 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Compressive Macroscopic Fluorescence Lifetime Imaging (MFLI) is a novel technical implementation that enables monitoring multiple molecular interactions in macroscopic scale. Especially, we reported recently on the development of a…

Medical Physics · Physics 2018-02-23 Ruoyang Yao , Marien Ochoa , Xavier Intes , Pingkun Yan

Coherent spin resonance techniques, such as nuclear and electron spin resonance spectroscopy, have revolutionized non-invasive imaging by providing spectrally resolved information about spin dynamics. Motivated by the recent emergence of…

Quantum Physics · Physics 2026-02-25 Santiago Beltrán-Romero , Stefan Löffler , Dennis Rätzel , Philipp Haslinger

Nuclear Magnetic Resonance (NMR) spectroscopy is a crucial analytical technique used for molecular structure elucidation, with applications spanning chemistry, biology, materials science, and medicine. However, the frequency resolution of…

Light field (LF) image super-resolution (SR) is a challenging problem due to its inherent ill-posed nature, where a single low-resolution (LR) input LF image can correspond to multiple potential super-resolved outcomes. Despite this…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Wentao Chao , Fuqing Duan , Xuechun Wang , Yingqian Wang , Guanghui Wang

The relative root mean squared errors (RMSE) of nonparametric methods for spectral estimation is compared for microwave scattering data of plasma fluctuations. These methods reduce the variance of the periodogram estimate by averaging the…

Applications · Statistics 2019-11-15 Kurt S. Riedel , Alexander Sidorenko , David J. Thomson

Fourier ptychographic microscopy (FPM) is a recently proposed quantitative phase imaging technique with high resolution and wide field-of-view (FOV). In current FPM imaging platforms, systematic error sources come from the aberrations, LED…

Instrumentation and Detectors · Physics 2017-09-18 An Pan , Yan Zhang , Tianyu Zhao , Zhaojun Wang , Dan Dan , Baoli Yao

Fourier ptychographic microscopy (FPM) is a recently developed computational imaging technique for wide-field, high-resolution microscopy with a high space-bandwidth product. It integrates the concepts of synthetic aperture and phase…

Optics · Physics 2021-12-30 Chuanjian Zheng , Shaohui Zhang , Guocheng Zhou , Yao Hu , Qun Hao

Structured illumination microscopy (SIM) has emerged as an essential technique for 3D and live-cell super-resolution imaging. However, to date, there has not been a dedicated workshop or journal issue covering the various aspects of SIM,…

Scanning fluorescence correlation spectroscopy (SFCS) with a scan path perpendicular to the membrane plane was introduced to measure diffusion and interactions of fluorescent components in free standing biomembranes. Using a confocal laser…

Biomolecules · Quantitative Biology 2018-06-04 Paul Müller , Petra Schwille , Thomas Weidemann

Audio super-resolution is challenging owing to its ill-posed nature. Recently, the application of diffusion models in audio super-resolution has shown promising results in alleviating this challenge. However, diffusion-based models have…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-12 Jun-Hak Yun , Seung-Bin Kim , Seong-Whan Lee

Structured illumination microscopy (SIM) provides images of fluorescent objects at an enhanced resolution greater than that of conventional epifluorescence wide-field microscopy. Initially demonstrated in 1999 to enhance the lateral…

Optics · Physics 2022-03-09 James D. Manton

Single-pixel imaging, with the advantages of a wide spectrum, beyond-visual-field imaging, and robustness to light scattering, has attracted increasing attention in recent years. Fourier single-pixel imaging (FSI) can reconstruct sharp…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Dong Zhou , Jie Cao , Huan Cui , Qun Hao , Bing-Kun Chen , Kai Lin
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