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Atherosclerosis is a state wherein plaque (fat, cholesterol, and different substances) develops inside the veins that in the end prompts carotid artery stenosis which is a phase of narrowing in the huge courses situated on either side of…

Medical Physics · Physics 2021-08-03 Nihal Ahmed , Ashfaq Ahmed , Sakan Binte Imran

Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid…

Medical Physics · Physics 2017-06-05 Ruchika Bhatia , Sharda Vashisth , Renu Saini

Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major…

The paper is devoted to a study of the peristaltic motion of blood in the micro-circulatory system. The vessel is considered to be of varying cross-section. The progressive peristaltic waves are taken to be of sinusoidal nature. Blood is…

Fluid Dynamics · Physics 2012-12-17 J. C. Misra , S. Maiti

Reduced blood flow, as occurring in ischemia or resulting from exposure to microgravity such as encountered in space flights, induces a decrease in the level of shear stress sensed by the endothelial cells forming the inner part of blood…

The role of Helical Flow (HF) in human coronary arteries remains uncertain, yet its understanding promises unprecedented insights into atherosclerotic processes. In this study, we investigated the effects of HF and key haemodynamic…

Medical Physics · Physics 2025-08-12 Chi Shen , Mingzi Zhang , Hamed Keramati , Diogo Almeida , Susann Beier

Atherosclerosis, a chronic inflammatory cardiovascular disease, leads to arterial constriction caused by the accumulation of lipids, cholesterol, and various substances within artery walls. Such plaque can rupture, resulting in a blood clot…

Tissues and Organs · Quantitative Biology 2024-08-07 Ruchira Ray , Bibaswan Dey

Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic syndrome. In these situations, low density lipoproteins (LDL) undergo oxidation. Oxidized LDL…

Biomolecules · Quantitative Biology 2024-09-25 Celine Luquain-Costaz , Isabelle Delton

Pulsating flows through tubular geometries are laminar provided that velocities are moderate. This in particular is also believed to apply to cardiovascular flows where inertial forces are typically too low to sustain turbulence. On the…

Fluid Dynamics · Physics 2020-05-26 Duo Xu , Atul Varshney , Xingyu Ma , Baofang Song , Michael Riedl , Marc Avila , Björn Hof

The link between atherosclerosis and blood flow-induced haemodynamic luminal shear stresses is well established. However, this understanding has not been translated into clinical practice because of the interdependent effects of the complex…

Medical Physics · Physics 2023-12-04 Mingzi Zhang , Ramtin Gharleghi , Chi Shen , Susann Beier

We study the rheological behavior of concentrated granular suspensions of simple spherical particles. Under controlled stress, the system exhibits an S-shaped flow curve (stress vs. shear rate) with a negative slope in between the…

Soft Condensed Matter · Physics 2015-09-23 Zhongcheng Pan , Henri de Cagny , Bart Weber , Daniel Bonn

A mathematical model of atherosclerosis of a blood vessel is advanced with regard for the entry of low-density lipoproteins (LDLs) into blood. For the first time, the influence of cytokines on the inflammation of a blood vessel at the…

Biological Physics · Physics 2025-03-25 V. I. Grytsay

There is growing evidence that the flow of driven amorphous solids is not homogeneous, even if the macroscopic stress is constant across the system. Via event driven molecular dynamics simulations of a hard sphere glass, we provide the…

Soft Condensed Matter · Physics 2015-06-04 Suvendu Mandal , Markus Gross , Dierk Raabe , Fathollah Varnik

Shear stress plays an important role in the creation and evolution of atherosclerosis. An key element for in-vivo measurements and extrapolations is the dependence of shear stress on body mass. In the case of a Poiseuille modeling of the…

Biological Physics · Physics 2018-02-20 G. Croizat , A. Kehren , H. Roux de Bézieux , A. Barakat

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

A bulk metallic glass forming alloy is subjected to shear flow in its supercooled state by compression of a short rod to produce a flat disc. The resulting material exhibits enhanced crystallization kinetics during isothermal annealing as…

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

Tissues and Organs · Quantitative Biology 2023-03-24 Jennifer Buoncore , Alexis Sobecki , Brian Lee Beatty

Shear thickening is a type of non-Newtonian behavior in which the stress required to shear a fluid increases faster than linearly with shear rate. Many concentrated suspensions of particles exhibit an especially dramatic version, known as…

Soft Condensed Matter · Physics 2015-06-16 Eric Brown , Heinrich M. Jaeger

A number of dense particle suspensions experience a dramatic increase in viscosity with the shear stress, up to a solid-like response. This shear-thickening process is understood as a transition under flow of the nature of the contacts,…

Soft Condensed Matter · Physics 2024-01-23 Anais Gauthier , Guillaume Ovarlez , Annie Colin

Isolated post-capillary pulmonary hypertension (Ipc-PH) occurs due to left heart failure, which contributes to 1 out of every 9 deaths in the United States. In some patients, through unknown mechanisms, Ipc-PH transitions to combined…

Tissues and Organs · Quantitative Biology 2021-03-11 Michelle A. Bartolo , M. Umar Qureshi , Mitchel J. Colebank , Naomi C. Chesler , Mette S. Olufsen
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