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Functional polymers, such as poly(ethylene glycol) (PEG) terminated with a single phosphonic acid, hereafter PEGik-Ph are often applied to coat metal oxide surfaces during post synthesis steps, but are not sufficient to stabilize sub-10 nm…

Cerium oxide nanoparticles are known to catalyze the decomposition of reactive oxygen species such as superoxide radical and hydrogen peroxide. Herein, we examine the superoxide dismutase (SOD) and catalase (CAT) mimetic catalytic…

Materials Science · Physics 2021-09-21 V. Baldim , F. Bedioui , N. Mignet , I. Margaill , J. -F. Berret

In a recent publication, we have highlighted the potential of phosphonic acid terminated PEG oligomers to functionalize strong UV absorption cerium oxide nanoparticles[1], which yield suspensions that are stable in aqueous or organic…

Materials Science · Physics 2013-05-07 L. Qi , J. Fresnais , P. Muller , O. Theodoly , J. -F. Berret , J. -P. Chapel

For applications in nanomedicine, particles need to be functionalized to prevent protein corona formation and or aggregation. Most advanced strategies take advantage of functional polymers and assembly techniques. Nowadays there is an…

Applied Physics · Physics 2021-09-21 V. Baldim , A. Graillot , N. Bia , C. Loubat , J. -F. Berret

In this feature article, we provide an overview of our research on statistical copolymers as a coating material for metal oxide nanoparticles and surfaces. These copolymers contain functional groups enabling non-covalent binding to oxide…

Soft Condensed Matter · Physics 2022-04-29 Jean-Francois Berret , Alain Graillot

Rare earth cerium oxide (ceria) nanoparticles are stabilized using end-functional phosphonated-PEG oligomers. The complexation process and structure of the resulting hybrid core-shell singlet nanocolloids are described, characterized and…

Soft Condensed Matter · Physics 2008-04-23 L. Qi , A. Sehgal , J. -C. Castaing , J. -P. Chapel , J. Fresnais , J. -F. Berret , F. Cousin

The ability to mimic protein-based oxidase with multi-functional inorganic nanozymes would greatly advance biomedical and clinical practices. Praseodymia (PrOx) nanorods (NRs) and nanoparticles (NPs) have been synthesized using hydrothermal…

Oxidative stress, which is one of the main harmful mechanisms of pathologies including is-chemic stroke, contributes to both neurons and endothelial cell damages, leading to vascular lesions. Although many antioxidants have been tested in…

Due to the increasing use of nanometric cerium oxide in applications, concerns about the toxicity of these particles have been raised and have resulted in a large number of investigations. We report here on the interactions between 7 nm…

Biological Physics · Physics 2013-08-06 N. Ould-Moussa , M. Safi , M. A. Guedeau-Boudeville , D. Montero , H. Conjeaud , J. F. Berret

In recent years, there has been a renewed interest in complex coacervation, driven by concerted efforts to offer novel experimental and theoretical insights into electrostatic charge-induced association. While previous studies have…

Soft Condensed Matter · Physics 2024-10-30 Letícia Vitorazi , Jean-François Berret

Applications of nanoparticles in biology require that the nanoparticles remain stable in solutions containing high concentrations of proteins and salts, as well as in cell culture media. In this work, we developed simple protocols for the…

Soft Condensed Matter · Physics 2009-07-07 B. Chanteau , J. Fresnais , J. -F. Berret

When disperse in biological fluids, engineered nanoparticles are selectively coated with proteins, resulting in the formation of a protein corona. It is suggested that the protein corona is critical in regulating the conditions of entry…

Materials Science · Physics 2021-09-21 V. Torrisi , A. Graillot , L. Vitorazi , Q. Crouzet , G. Marletta , C. Loubat , J. -F. Berret

Recent surveys have shown that the number of nanoparticle-based formulations actually used at the clinical level is significantly lower than expected a decade ago. One reason for this is that the nanoparticle physicochemical properties fall…

With the global transition towards cleaner energy and sustainable processes, the demand for efficient catalysts, especially for the oxygen reduction reaction, has gained attention from the scientific community. This research work…

Materials Science · Physics 2025-05-12 Lanna E. B. Lucchetti , Pedro A. S. Autreto , Mauro C. Santos , James M. de Almeida

Understanding the complex chemistry of functional nanomaterials is of fundamental importance. Controlled synthesis and characterization at the atomic level is essential to gain deeper insight into the unique chemical reactivity exhibited by…

Reactive oxygen species (ROS), which are expressed at high levels in many diseases, can be scavenged by cerium oxide nanoparticles (CeO2NPs). CeO2NPs can cause significant cytotoxicity when administered directly to cells, but this…

Cell Behavior · Quantitative Biology 2024-04-29 Ummay Mowshome Jahan , Brianna Blevins , Sergiy Minko , Vladimir Reukov

The exceptional conducting nature of graphene makes it a viable candidate for enhancing the effectiveness of photocatalytic and biomedical nanomaterials. Herein, the immobilization of monodispersed silicon dioxide (SiO2) nanoparticles on…

Applied Physics · Physics 2017-08-23 Aqsa Arshad , Javed Iqbal , Qaisar Mansoor , Ishaq Ahmad

Recent nanotoxicity studies revealed that the physico-chemical characteristics of engineered nanomaterials play an important role in the interactions with living cells. Here, we report on the toxicity and uptake of the cerium and iron oxide…

Materials Science · Physics 2010-11-09 M. Safi , H. Sarrouj , O. Sandre , N. Mignet , J. -F. Berret

When polyelectrolyte-neutral block copolymers are mixed in solutions to oppositely charged species (e.g. surfactant micelles, macromolecules, proteins etc), there is the formation of stable supermicellar aggregates combining both…

Soft Condensed Matter · Physics 2007-05-23 J. -F. Berret , K. Yokota , M. Morvan

Cerium oxide nanoparticles (CNPs) have recently gained increasing interest as redox enzyme-mimetics to scavenge the intracellular excess of reactive oxygen species, including hydrogen peroxide (H2O2). Despite the extensive exploration of…

Soft Condensed Matter · Physics 2023-09-26 Giusy Finocchiaro , Xiaohui Ju , Braham Mezghrani , Jean-François Berret
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