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Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

In this paper, we study how pixel size influences energy resolution for a proposed pixelated detector---a high sensitivity, low cost, and real-time radon monitor based on \textit{Topmetal-${II}^-$} time projection chamber (TPC). Using…

Instrumentation and Detectors · Physics 2019-01-08 Mengyao Huang , Hua Pei , Xiangming Sun , Shuguang Zou

We have been developing the SOI pixel detector ``INTPIX'' for space use and general purpose applications such as the residual stress measurement of a rail and high energy physics experiments. INTPIX is a monolithic pixel detector composed…

Physical and biological range uncertainties limit the clinical potential of Proton Beam Therapy (PBT). In this proceedings, we report on two research projects, which we are conducting in parallel and which both tackle the problem of range…

A new pixel detector for the CMS experiment was built in order to cope with the instantaneous luminosities anticipated for the Phase~I Upgrade of the LHC. The new CMS pixel detector provides four-hit tracking with a reduced material budget…

Instrumentation and Detectors · Physics 2017-06-02 M. Dragicevic , M. Friedl , J. Hrubec , H. Steininger , A. Gädda , J. Härkönen , T. Lampén , P. Luukka , T. Peltola , E. Tuominen , E. Tuovinen , A. Winkler , P. Eerola , T. Tuuva , G. Baulieu , G. Boudoul , L. Caponetto , C. Combaret , D. Contardo , T. Dupasquier , G. Gallbit , N. Lumb , L. Mirabito , S. Perries , M. Vander Donckt , S. Viret , C. Bonnin , L. Charles , L. Gross , J. Hosselet , D. Tromson , L. Feld , W. Karpinski , K. Klein , M. Lipinski , G. Pierschel , M. Preuten , M. Rauch , M. Wlochal , M. Aldaya , C. Asawatangtrakuldee , K. Beernaert , D. Bertsche , C. Contreras-Campana , G. Eckerlin , D. Eckstein , T. Eichhorn , E. Gallo , J. Garay Garcia , K. Hansen , M. Haranko , A. Harb , J. Hauk , J. Keaveney , A. Kalogeropoulos , C. Kleinwort , W. Lohmann , R. Mankel , H. Maser , G. Mittag , C. Muhl , A. Mussgiller , D. Pitzl , O. Reichelt , M. Savitskyi , P. Schütze , V. Sola , S. Spannagel , R. Walsh , A. Zuber , H. Biskop , P. Buhmann , M. Centis-Vignali , E. Garutti , J. Haller , M. Hoffmann , R. Klanner , T. Lapsien , M. Matysek , A. Perieanu , Ch. Scharf , P. Schleper , A. Schmidt , J. Schwandt , J. Sonneveld , G. Steinbrück , B. Vormwald , J. Wellhausen , M. Abbas , C. Amstutz , T. Barvich , Ch. Barth , F. Boegelspacher , W. De Boer , E. Butz , M. Casele , F. Colombo , A. Dierlamm , B. Freund , F. Hartmann , S. Heindl , U. Husemann , A. Kornmeyer , S. Kudella , Th. Muller , H. J. Simonis , P. Steck , M. Weber , Th. Weiler , T. Kiss , F. Siklér , T. Tölyhi , V. Veszprémi , P. Cariola , D. Creanza , M. De Palma , G. De Robertis , L. Fiore , M. Franco , F. Loddo , G. Sala , L. Silvestris , G. Maggi , S. My , G. Selvaggi , S. Albergo , G. Cappello , S. Costa , A. Di Mattia , F. Giordano , R. Potenza , M. A. Saizu , A. Tricomi , C. Tuve , E. Focardi , M. E. Dinardo , S. Fiorendi , S. Gennai , S. Malvezzi , R. A. Manzoni , D. Menasce , L. Moroni , D. Pedrini , P. Azzi , N. Bacchetta , D. Bisello , M. Dall'Osso , N. Pozzobon , M. Tosi , L. Alunni Solestizi , M. Biasini , G. M. Bilei , C. Cecchi , B. Checcucci , D. Ciangottini , L. Fanò , C. Gentsos , M. Ionica , R. Leonardi , E. Manoni , G. Mantovani , S. Marconi , V. Mariani , M. Menichelli , A. Modak , A. Morozzi , F. Moscatelli , D. Passeri , P. Placidi , V. Postolache , A. Rossi , A. Saha , A. Santocchia , L. Storchi , D. Spiga , K. Androsov , P. Azzurri , G. Bagliesi , A. Basti , T. Boccali , L. Borrello , F. Bosi , R. Castaldi , M. Ceccanti , M. A. Ciocci , R. Dell'Orso , S. Donato , G. Fedi , A. Giassi , M. T. Grippo , F. Ligabue , G. Magazzu , P. Mammini , F. Mariani , E. Mazzoni , A. Messineo , A. Moggi , F. Morsani , F. Palla , F. Palmonari , A. Profeti , F. Raffaelli , A. Ragonesi , A. Rizzi , A. Soldani , P. Spagnolo , R. Tenchini , G. Tonelli , A. Venturi , P. G. Verdini , D. Abbaneo , I. Ahmed , E. Albert , G. Auzinger , G. Berruti , J. Bonnaud , J. Daguin , A. D'Auria , S. Detraz , O. Dondelewski , B. Engegaard , F. Faccio , N. Frank , K. Gill , A. Honma , A. Kornmayer , A. Labaza , F. Manolescu , I. McGill , S. Mersi , S. Michelis , A. Onnela , M. Ostrega , S. Pavis , A. Peisert , J. -F. Pernot , P. Petagna , H. Postema , K. Rapacz , C. Sigaud , P. Tropea , J. Troska , A. Tsirou , F. Vasey , B. Verlaat , P. Vichoudis , L. Zwalinski , F. Bachmair , R. Becker , D. di Calafiori , B. Casal , P. Berger , L. Djambazov , M. Donega , C. Grab , D. Hits , J. Hoss , G. Kasieczka , W. Lustermann , B. Mangano , M. Marionneau , P. Martinez Ruiz del Arbol , M. Masciovecchio , M. Meinhard , L. Perozzi , U. Roeser , A. Starodumov , V. Tavolaro , R. Wallny , D. Zhu , K. Bösiger , L. Caminada , F. Canelli , V. Chiochia , A. de Cosa , C. Galloni , T. Hreus , B. Kilminster , C. Lange , R. Maier , J. Ngadiuba , D. Pinna , P. Robmann , S. Taroni , Y. Yang , W. Bertl , K. Deiters , W. Erdmann , R. Horisberger , H. -C. Kaestli , D. Kotlinski , U. Langenegger , B. Meier , T. Rohe , S. Streuli , P. -H. Chen , C. Dietz , F. Fiori , U. Grundler , W. -S. Hou , R. -S. Lu , M. Moya , J. -F. Tsai , Y. M. Tzeng , D. Cussans , J. Goldstein , M. Grimes , D. Newbold , P. Hobson , I. D. Reid , G. Auzinger , R. Bainbridge , P. Dauncey , G. Hall , T. James , A. -M. Magnan , M. Pesaresi , D. M. Raymond , K. Uchida , T. Durkin , K. Harder , C. Shepherd-Themistocleous , M. Chertok , J. Conway , R. Conway , C. Flores , R. Lander , D. Pellett , F. Ricci-Tam , M. Squires , J. Thomson , R. Yohay , K. Burt , J. Ellison , G. Hanson , M. Olmedo , W. Si , B. R. Yates , A. Dominguez , R. Bartek , B. Bentele , J. P. Cumalat , W. T. Ford , F. Jensen , A. Johnson , M. Krohn , S. Leontsinis , T. Mulholland , K. Stenson , S. R. Wagner , A. Apresyan , G. Bolla , K. Burkett , J. N. Butler , A. Canepa , H. W. K. Cheung , D. Christian , W. E. Cooper , G. Deptuch , G. Derylo , C. Gingu , S. Grünendahl , S. Hasegawa , J. Hoff , J. Howell , M. Hrycyk , S. Jindariani , M. Johnson , F. Kahlid , S. Kwan , C. M. Lei , R. Lipton , R. Lopes De Sá , T. Liu , S. Los , M. Matulik , P. Merkel , S. Nahn , A. Prosser , R. Rivera , B. Schneider , G. Sellberg , A. Shenai , K. Siehl , L. Spiegel , N. Tran , L. Uplegger , E. Voirin , D. R. Berry , X. Chen , L. Ennesser , A. Evdokimov , C. E. Gerber , S. Makauda , C. Mills , I. D. Sandoval Gonzalez , J. Alimena , L. J. Antonelli , B. Francis , A. Hart , C. S. Hill , N. Parashar , J. Stupak , D. Bortoletto , M. Bubna , N. Hinton , M. Jones , D. H. Miller , X. Shi , P. Baringer , A. Bean , S. Khalil , A. Kropivnitskaya , D. Majumder , E. Schmitz , G. Wilson , A. Ivanov , R. Mendis , T. Mitchell , N. Skhirtladze , R. Taylor , I. Anderson , D. Fehling , A. Gritsan , P. Maksimovic , C. Martin , K. Nash , M. Osherson , M. Swartz , M. Xiao , J. G. Acosta , L. M. Cremaldi , S. Oliveros , L. Perera , D. Summers , K. Bloom , D. R. Claes , C. Fangmeier , R. Gonzalez Suarez , J. Monroy , J. Siado , E. Bartz , Y. Gershtein , E. Halkiadakis , S. Kyriacou , A. Lath , K. Nash , M. Osherson , S. Schnetzer , R. Stone , M. Walker , S. Malik , S. Norberg , J. E. Ramirez Vargas , M. Alyari , J. Dolen , A. Godshalk , C. Harrington , I. Iashvili , A. Kharchilava , D. Nguyen , A. Parker , S. Rappoccio , B. Roozbahani , J. Alexander , J. Chaves , J. Chu , S. Dittmer , K. McDermott , N. Mirman , A. Rinkevicius , A. Ryd , E. Salvati , L. Skinnari , L. Soffi , Z. Tao , J. Thom , J. Tucker , M. Zientek , B. Akgün , K. M. Ecklund , M. Kilpatrick , T. Nussbaum , J. Zabel , P. D'Angelo , W. Johns , K. Rose

A novel method to estimate the pixels simultaneous detection probability and the spatial resolution of pixelized detectors is proposed, which is based on the determination of the statistical correlations between detector neighbor pixels.…

Medical Physics · Physics 2008-02-25 V. Grabski

Single-pixel imaging, originally developed in light optics, facilitates fast three-dimensional sample reconstruction, as well as probing with light wavelengths undetectable by conventional multi-pixel detectors. However, the spatial…

The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly…

In Charge Coupled Device (CCD) detectors the electrons excited upon absorption of a single x-ray photon quickly diffuse and generate charge-spots often larger than pixel dimensions. In the soft x-ray range this phenomenon drastically limits…

Instrumentation and Detectors · Physics 2014-10-08 Andrea Amorese , Greta Dellea , Lucio Braicovich , Giacomo Ghiringhelli

A Monte Carlo simulation has been developed to predict the spatial resolution of silicon pixel detectors. The results discussed in this paper focus on the unit cell geometry of 50 $\mu$m x 400 $\mu$m, as chosen for BTeV. Effects taken into…

High Energy Physics - Experiment · Physics 2009-10-31 Marina Artuso , Jianchun Wang

Positron Emission Particle Tracking (PEPT) is an imaging method for the visualization of fluid motion, capable of reconstructing three-dimensional trajectories of small tracer particles suspended in nearly any medium, including fluids that…

Instrumentation and Detectors · Physics 2023-03-20 Avshalom Offner , Sam Manger , Jacques Vanneste

Single particle diffraction imaging experiments at free-electron lasers (FEL) have a great potential for structure determination of reproducible biological specimens that can not be crystallized. One of the challenges in processing the data…

Biological Physics · Physics 2013-10-16 O. M. Yefanov , I. A. Vartanyants

Silicon tracking detectors can record the charge in each channel (analog or digitized) or have only binary readout (hit or no hit). While there is significant literature on the position resolution obtained from interpolation of charge…

Instrumentation and Detectors · Physics 2018-06-13 Fuyue Wang , Benjamin Nachman , Maurice Garcia-Sciveres

Single molecule X-ray scattering experiments using free electron lasers hold the potential to resolve both single structures and structural ensembles of biomolecules. However, molecular electron density determination has so far not been…

Computational Physics · Physics 2026-04-17 Steffen Schultze , Helmut Grubmüller

Light detection and ranging systems reconstruct scene depth from time-of-flight measurements. For low light-level depth imaging applications, such as remote sensing and robot vision, these systems use single-photon detectors that resolve…

Applications · Statistics 2015-10-28 Dongeek Shin , Jeffrey H. Shapiro , Vivek K Goyal

Optical systems capable of generating fields with sub-wavelength spatial features have become standard in science and engineering research and industry. Pertinent examples include atom- and ion-based quantum computers and optical…

Atomic Physics · Physics 2025-11-18 Nikhil Kotibhaskar , Sainath Motlakunta , Anthony Vogliano , Lewis Hahn , Rajibul Islam

Under weak illumination, tracking and imaging moving object turns out to be hard. By spatially collecting the signal, single pixel imaging schemes promise the capability of image reconstruction from low photon flux. However, due to the…

Diffusion coefficient measurements are important for many biological and material investigations, such as particle dynamics, kinetics, and size determinations. Amongst current measurement methods, single particle tracking (SPT) offers the…

Biomolecules · Quantitative Biology 2011-07-12 Shannon Kian Zareh , Michael C. DeSantis , Jonathan Kessler , Je-Luen Li , Y. M. Wang

Introduction: Real-time dosimetry of surface doses in electron beams has not been widely established yet. Plastic scintillation detectors (PSD) promise high spatial resolution and real-time dosimetry with minimum perturbation of the…

Optoplasmonic methods capable of single protein detection so far rely on analyte immobilization in order to facilitate detection [1-6]. These detection schemes, even if they facilitate transient single-molecule detection [7,8] via…

Optics · Physics 2022-01-21 M. D. Baaske , N. Asgari , D. Punj , M. Orrit