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To make DNA a suitable medium for archival data storage, it is essential to consider the decay process of the strands observed in DNA storage systems. This paper studies the decay process as a probabilistic noisy torn paper channel (TPC),…

Information Theory · Computer Science 2026-01-19 Frederik Walter , Maria Abu-Sini , Nils Weinhardt , Antonia Wachter-Zeh

Regenerating codes are a class of codes proposed for providing reliability of data and efficient repair of failed nodes in distributed storage systems. In this paper, we address the fundamental problem of handling errors and erasures during…

Information Theory · Computer Science 2015-03-20 K. V. Rashmi , Nihar B. Shah , Kannan Ramchandran , P. Vijay Kumar

Erasure correcting codes are widely used to ensure data persistence in distributed storage systems. This paper addresses the simultaneous repair of multiple failures in such codes. We go beyond existing work (i.e., regenerating codes by…

Information Theory · Computer Science 2013-09-18 Anne-Marie Kermarrec , Gilles Straub , Nicolas Le Scouarnec

Training a deep neural network heavily relies on a large amount of training data with accurate annotations. To alleviate this problem, various methods have been proposed to annotate the data automatically. However, automatically generating…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Yi Wei , Xue Mei , Xin Liu , Pengxiang Xu

A family of high rate quantum error correcting codes adapted to the amplitude damping channel is presented. These codes are nonadditive and exploit self-complementarity structure to correct all first-order errors. Their rates can be higher…

Quantum Physics · Physics 2007-12-18 Ruitian Lang , Peter W. Shor

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

Information Theory · Computer Science 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

DNA-based data storage systems face practical challenges due to the high cost of DNA synthesis. A strategy to address the problem entails encoding data via topological modifications of the DNA sugar-phosphate backbone. The DNA Punchcards…

Emerging Technologies · Computer Science 2025-05-07 Jin Sima , Chao Pan , S. Kasra Tabatabaei , Alvaro G. Hernandez , Charles M. Schroeder , Olgica Milenkovic

Sequencing a DNA strand, as part of the read process in DNA storage, produces multiple noisy copies which can be combined to produce better estimates of the original strand; this is called trace reconstruction. One can reduce the error rate…

Information Theory · Computer Science 2024-08-22 Sundara Rajan Srinivasavaradhan , Sivakanth Gopi , Henry D. Pfister , Sergey Yekhanin

DNA sequences are prone to creating secondary structures by folding back on themselves by non-specific hybridization among its nucleotides. The formation of secondary structures makes the sequences chemically inactive towards synthesis and…

Information Theory · Computer Science 2022-11-30 Siddhartha Siddhiprada Bhoi , Paramapalli Udaya , Abhay Kumar Singh

Quantum noise fundamentally limits the utility of near-term quantum devices, making error mitigation essential for practical quantum computation. While traditional quantum error correction codes require substantial qubit overhead and…

Quantum Physics · Physics 2025-09-23 Karan Kendre

Reliability is an important requirement for both communication and storage systems. Due to continuous scale down of technology multiple adjacent bits error probability increases. The data may be corrupted due soft errors. Error correction…

Hardware Architecture · Computer Science 2020-02-19 Sayan Tripathi , Jhilam Jana , Jaydeb Bhaumik

The last decade has witnessed the breakthrough of deep neural networks (DNNs) in many fields. With the increasing depth of DNNs, hundreds of millions of multiply-and-accumulate (MAC) operations need to be executed. To accelerate such…

Hardware Architecture · Computer Science 2022-11-29 Amro Eldebiky , Grace Li Zhang , Georg Boecherer , Bing Li , Ulf Schlichtmann

Nanopore sequencing is an emerging DNA sequencing technology that has been proposed for use in DNA storage systems. We propose the noisy nanopore channel model for nanopore sequencing. This model captures duplications, inter-symbol…

Information Theory · Computer Science 2022-05-10 Brendon McBain , Emanuele Viterbo , James Saunderson

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and trade-offs of DNA-based storage systems by introducing a new channel model, which we…

Information Theory · Computer Science 2020-01-20 Ilan Shomorony , Reinhard Heckel

Motivated by DNA-based storage, we study the noisy shuffling channel, which can be seen as the concatenation of a standard noisy channel (such as the BSC) and a shuffling channel, which breaks the data block into small pieces and shuffles…

Information Theory · Computer Science 2019-03-01 Ilan Shomorony , Reinhard Heckel

We consider the problem of designing low-redundancy codes in settings where one must correct deletions in conjunction with substitutions or adjacent transpositions; a combination of errors that is usually observed in DNA-based data storage.…

Information Theory · Computer Science 2021-12-21 Ryan Gabrys , Venkatesan Guruswami , João Ribeiro , Ke Wu

Supervised learning on Deep Neural Networks (DNNs) is data hungry. Optimizing performance of DNN in the presence of noisy labels has become of paramount importance since collecting a large dataset will usually bring in noisy labels.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Shuyu Kong , You Li , Jia Wang , Amin Rezaei , Hai Zhou

This paper describes a new asynchronous algorithm and implementation for the problem of k-mer counting (KC), which concerns quantifying the frequency of length k substrings in a DNA sequence. This operation is common to many computational…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-08 Souvadra Hati , Akihiro Hayashi , Richard Vuduc

Correcting insertions/deletions as well as substitution errors simultaneously plays an important role in DNA-based storage systems as well as in classical communications. This paper deals with the fundamental task of constructing codes that…

Information Theory · Computer Science 2020-05-20 Ilia Smagloy , Lorenz Welter , Antonia Wachter-Zeh , Eitan Yaakobi

The biggest challenge when using DNA as a storage medium is maintaining its stability. The relative occurrence of Guanine (G) and Cytosine (C) is essential for the longevity of DNA. In addition to that, reverse complementary base pairs…

Information Theory · Computer Science 2023-08-03 NallappaBhavithran G , Selvakumar R