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Different evolutionary models are known to make disparate predictions for the success of an invading mutant in some situations. For example, some evolutionary mechanics lead to amplification of selection in structured populations, while…

Populations and Evolution · Quantitative Biology 2020-07-01 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

In this paper we present a hydrodynamic approach to describe the motion of migrating bacteria as a special class of self-propelled systems. Analytical and numerical calculations has been performed to study the behavior of our model in the…

Soft Condensed Matter · Physics 2015-06-25 Zoltan Csahok , Andras Czirok

The near-surface swimming patterns of bacteria are strongly determined by the hydrodynamic interactions between bacteria and the surface, which trap bacteria in smooth circular trajectories that lead to inefficient surface exploration.…

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

Biological Physics · Physics 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

Bacteria in biofilms form complex structures and can collectively migrate within mobile aggregates, which is referred to as swarming. This behavior is influenced by a combination of various factors, including morphological characteristics…

Soft Condensed Matter · Physics 2024-01-19 Bohan Wu-Zhang , Dmitry A. Fedosov , Gerhard Gompper

Microorganisms ofter move in confined, disordered environments, where hydrodynamic couplings can modify their transport behavior. Using extensive finite-element simulations, we investigate the dynamics of microswimmers -- modeled as…

Soft Condensed Matter · Physics 2026-03-24 Mirko Residori , Sebastian Aland , Christina Kurzthaler

We study memory based random walk models to understand diffusive motion in crowded heterogeneous environment. The models considered are non-Markovian as the current move of the random walk models is determined by randomly selecting a move…

Statistical Mechanics · Physics 2018-08-01 Sabeeha Hasnain , Upendra Harbola , Pradipta Bandyopadhyay

Self-propelled micron-size particles suspended in a fluid, like bacteria or synthetic microswimmers, are strongly non-equilibrium systems where particle motility breaks the microscopic detailed balance, often resulting in large-scale…

Soft Condensed Matter · Physics 2024-03-15 Dóra Bárdfalvy , Viktor Škultéty , Cesare Nardini , Alexander Morozov , Joakim Stenhammar

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

Soft Condensed Matter · Physics 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

Collective migration dominates many phenomena, from cell movement in living systems to abiotic self-propelling particles. Focusing on the early stages of tumor evolution, we enunciate the principles involved in cell dynamics and highlight…

Cell Behavior · Quantitative Biology 2018-05-02 Abdul N Malmi-Kakkada , Xin Li , Himadri S. Samanta , Sumit Sinha , D. Thirumalai

Collective motion of cells is critical to some of the most vital tasks including wound healing, development, and immune response [Friedl and Gilmour 2009; Tokarski et al. 2012; Lee et al. 2012; Beltman et al. 2009], and is common to many…

Cell Behavior · Quantitative Biology 2014-07-04 Mircea Davidescu , Iain Couzin

We study transport of interacting particles in weakly disordered media. Our one-dimensional system includes (i) disorder: the hopping rate governing the movement of a particle between two neighboring lattice sites is inhomogeneous, and (ii)…

Statistical Mechanics · Physics 2009-05-13 E. Ben-Naim , P. L. Krapivsky

Swimming micro-organisms such as bacteria or spermatozoa are typically found in dense suspensions, and exhibit collective modes of locomotion qualitatively different from that displayed by isolated cells. In the dilute limit where…

Biological Physics · Physics 2010-05-02 Sebastien Michelin , Eric Lauga

Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for…

Statistical Mechanics · Physics 2012-09-06 M. E. Cates

The compartmentalization of distinct templates in protocells and the exchange of templates between them (migration) are key elements of a modern scenario for prebiotic evolution. Here we use the diffusion approximation of population…

Populations and Evolution · Quantitative Biology 2014-03-27 Jose F. Fontanari , Maurizio Serva

Collective cell migration plays an essential role in various biological processes, such as development or cancer proliferation. While cell-cell interactions are clearly key determinants of collective cell migration -- in addition to…

We investigate the emergence of subdiffusive transport by obstruction in continuum models for molecular crowding. While the underlying percolation transition for the accessible space displays universal behavior, the dynamic properties…

The flow of deformable particles, such as droplets, dragged by a fluid, through a network of narrow pores inside rocks or other porous media is key in a range of applications, from enhanced oil recovery and water filtration to lab on a chip…

Eukaryotic swimming cells such as spermatozoa, algae or protozoa use flagella or cilia to move in viscous fluids. The motion of their flexible appendages in the surrounding fluid induces propulsive forces that balance with the viscous drag…

Soft Condensed Matter · Physics 2023-10-06 Maciej Lisicki , Marcos F. Velho Rodrigues , Eric Lauga

Microtubules are an essential physical building block of cellular systems. They are organized using specific crosslinkers, motors, and influencers of nucleation and growth. With the addition of anti-parallel crosslinkers, microtubule…

Biological Physics · Physics 2021-06-23 Sumon Sahu , Lena Herbst , Ryan Quinn , Jennifer L. Ross