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Continuous Conditional Generative Modeling (CCGM) estimates high-dimensional data distributions, such as images, conditioned on scalar continuous variables (aka regression labels). While Continuous Conditional Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Xin Ding , Yongwei Wang , Kao Zhang , Z. Jane Wang

Understanding and developing a correlation measure that can detect general dependencies is not only imperative to statistics and machine learning, but also crucial to general scientific discovery in the big data age. In this paper, we…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Carey E. Priebe , Joshua T. Vogelstein

Data-dependent metrics are powerful tools for learning the underlying structure of high-dimensional data. This article develops and analyzes a data-dependent metric known as diffusion state distance (DSD), which compares points using a…

Machine Learning · Statistics 2020-03-10 Lenore Cowen , Kapil Devkota , Xiaozhe Hu , James M. Murphy , Kaiyi Wu

Effective diabetes management requires continuous monitoring of glycemic levels. Clinically, glycemic control is assessed using metrics such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR), typically derived from…

Machine Learning · Computer Science 2026-05-21 Canyu Lei , David Repaske , Jianxin Xie

In this study, we present a non-invasive glucose prediction system that integrates Near-Infrared (NIR) spectroscopy and millimeter-wave (mm-wave) sensing. We employ a Mixed Linear Model (MixedLM) to analyze the association between mm-wave…

Machine Learning · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…

Machine Learning · Computer Science 2021-05-19 Jeremy Beauchamp , Razvan Bunescu , Cindy Marling , Zhongen Li , Chang Liu

Motifs are a powerful tool for analyzing physiological waveform data. Standard motif methods, however, ignore important contextual information (e.g., what the patient was doing at the time the data were collected). We hypothesize that these…

Machine Learning · Computer Science 2019-04-09 Ian Fox , Lynn Ang , Mamta Jaiswal , Rodica Pop-Busui , Jenna Wiens

Understanding the complex relationships of biomarkers in diabetes is pivotal for advancing treatment strategies, a pressing need in diabetes research. This study applies Bayesian network structure learning to analyze the Shanghai Type 1 and…

Quantitative Methods · Quantitative Biology 2024-06-26 Yuyang Sun , Jingyu Lei , Panagiotis Kosmas

Every year, humanity loses about 1.5 million persons due to diabetic disease. Therefore continuous monitoring of diabetes is highly needed, but the conventional approach, i.e., fingertip pricking, causes mental and physical pain to the…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Abdelrhman Y. Soliman , Ahmed M. Nor , Octavian Fratu , Simona Halunga , Osama A. Omer , Ahmed S. Mubark

Complex multivariate time series arise in many fields, ranging from computer vision to robotics or medicine. Often we are interested in the independent underlying factors that give rise to the high-dimensional data we are observing. While…

Machine Learning · Statistics 2021-02-11 Simon Bing , Vincent Fortuin , Gunnar Rätsch

We present a method to estimate parameters in pharmacokinetic (PK) and pharmacodynamic (PD) models for glucose insulin dynamics in humans. The method combines 1) experimental glucose infusion rate (GIR) data from glucose clamp studies and…

Quantitative Methods · Quantitative Biology 2024-06-06 Kirstine Sylvest Freil , Liv Olivia Fritzen , Dimitri Boiroux , Tinna B. Aradottir , John Bagterp Jørgensen

Discrete-state denoising diffusion models led to state-of-the-art performance in graph generation, especially in the molecular domain. Recently, they have been transposed to continuous time, allowing more flexibility in the reverse process…

Machine Learning · Computer Science 2024-10-07 Antoine Siraudin , Fragkiskos D. Malliaros , Christopher Morris

We introduce graph gamma process (GGP) linear dynamical systems to model real-valued multivariate time series. For temporal pattern discovery, the latent representation under the model is used to decompose the time series into a…

Methodology · Statistics 2020-07-28 Rahi Kalantari , Mingyuan Zhou

To empower users of wearable medical devices, it is important to enable methods that facilitate reflection on previous care to improve future outcomes. In this work, we conducted a two-phase user-study involving patients, caregivers, and…

Computers and Society · Computer Science 2020-07-28 Temiloluwa Prioleau , Ashutosh Sabharwal , Madhuri M. Vasudevan

We evaluate the benefits of combining different offline and online data assimilation methodologies to improve personalized blood glucose prediction with type 2 diabetes self-monitoring data. We collect self-monitoring data (nutritional…

Quantitative Methods · Quantitative Biology 2017-09-04 Matthew E Levine , George Hripcsak , Lena Mamykina , Andrew Stuart , David J Albers

The life of a cell is governed by highly dynamical microscopic processes. Two notable examples are the diffusion of membrane receptors and the kinetics of transcription factors governing the rates of gene expression. Different fluorescence…

Quantitative Methods · Quantitative Biology 2020-04-03 Maxime Woringer , Ignacio Izeddin , Cyril Favard , Hugues Berry

Background: Type 1 diabetes (T1D) has seen a rapid evolution in management technology and forms a useful case study for the future management of other chronic conditions. Further development of this management technology requires an…

Human-Computer Interaction · Computer Science 2025-07-25 Sam Gordon James , Miranda Elaine Glynis Armstrong , Aisling Ann O'Kane , Harry Emerson , Zahraa S. Abdallah

Hypoglycemia is a severe condition of decreased blood glucose, specifically below 70 mg/dL (3.9 mmol/L). This condition can often be asymptomatic and challenging to predict in individuals with type 1 diabetes (T1D). Research on hypoglycemic…

Quantitative Methods · Quantitative Biology 2026-03-24 Vaibhav Gupta , Florian Grensing , Beyza Cinar , Louisa van den Boom , Maria Maleshkova

This research presents a smart urinary health monitoring system incorporating a coplanar waveguide (CPW)-fed slot-loop antenna biosensor designed to analyse various urine samples. The antenna demonstrates distinct resonant frequency shifts…

Systems and Control · Electrical Eng. & Systems 2025-09-24 Khan Masood Parvez , Sk Md Abidar Rahaman , Ali Shiri Sichani , Hadi AliAkbarpour

The characteristics and determinants of health and disease are often organised in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Though a…