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The absence of well-structured large datasets in medical computer vision results in decreased performance of automated systems and, especially, of deep learning models. Domain generalization techniques aim to approach unknown domains from a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Nikolaos Spanos , Anastasios Arsenos , Paraskevi-Antonia Theofilou , Paraskevi Tzouveli , Athanasios Voulodimos , Stefanos Kollias

Domain generalization (DG) aims to incorporate knowledge from multiple source domains into a single model that could generalize well on unseen target domains. This problem is ubiquitous in practice since the distributions of the target data…

Machine Learning · Statistics 2019-07-26 Shoubo Hu , Kun Zhang , Zhitang Chen , Laiwan Chan

The generalization of deep neural networks to unknown domains is a major challenge despite their tremendous progress in recent years. For this reason, the dynamic area of domain generalization (DG) has emerged. In contrast to unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Manuel Schwonberg , Hanno Gottschalk

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Supervised learning results typically rely on assumptions of i.i.d. data. Unfortunately, those assumptions are commonly violated in practice. In this work, we tackle such problem by focusing on domain generalization: a formalization where…

Machine Learning · Computer Science 2024-10-30 Isabela Albuquerque , João Monteiro , Mohammad Darvishi , Tiago H. Falk , Ioannis Mitliagkas

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Most statistical learning algorithms rely on an over-simplified assumption, that is, the train and test data are independent and identically distributed. In real-world scenarios, however, it is common for models to encounter data from new…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Zheyuan Zhang , Bin Wang , Lanhong Yao , Ugur Demir , Debesh Jha , Ismail Baris Turkbey , Boqing Gong , Ulas Bagci

Domain generalization aims to learn a prediction model on multi-domain source data such that the model can generalize to a target domain with unknown statistics. Most existing approaches have been developed under the assumption that the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Jin Kim , Jiyoung Lee , Jungin Park , Dongbo Min , Kwanghoon Sohn

Widely used traditional supervised deep learning methods require a large number of training samples but often fail to generalize on unseen datasets. Therefore, a more general application of any trained model is quite limited for medical…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Rabindra Khadga , Debesh Jha , Steven Hicks , Vajira Thambawita , Michael A. Riegler , Sharib Ali , Pål Halvorsen

Despite remarkable success in a variety of applications, it is well-known that deep learning can fail catastrophically when presented with out-of-distribution data. Toward addressing this challenge, we consider the domain generalization…

Machine Learning · Statistics 2021-11-16 Alexander Robey , George J. Pappas , Hamed Hassani

Domain generalization (DG) aims to generalize a model trained on multiple source (i.e., training) domains to a distributionally different target (i.e., test) domain. In contrast to the conventional DG that strictly requires the availability…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Zijian Wang , Yadan Luo , Ruihong Qiu , Zi Huang , Mahsa Baktashmotlagh

Machine learning models are intrinsically vulnerable to domain shift between training and testing data, resulting in poor performance in novel domains. Domain generalization (DG) aims to overcome the problem by leveraging multiple source…

Computer Vision and Pattern Recognition · Computer Science 2022-10-27 Tingwei Wang , Da Li , Kaiyang Zhou , Tao Xiang , Yi-Zhe Song

Domain adaption (DA) and domain generalization (DG) are two closely related methods which are both concerned with the task of assigning labels to an unlabeled data set. The only dissimilarity between these approaches is that DA can access…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Mohammad Mahfujur Rahman , Clinton Fookes , Mahsa Baktashmotlagh , Sridha Sridharan

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Domain generalization (DG) has been a hot topic in image recognition, with a goal to train a general model that can perform well on unseen domains. Recently, federated learning (FL), an emerging machine learning paradigm to train a global…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Junming Chen , Meirui Jiang , Qi Dou , Qifeng Chen

Medical image analysis (MedIA) has become an essential tool in medicine and healthcare, aiding in disease diagnosis, prognosis, and treatment planning, and recent successes in deep learning (DL) have made significant contributions to its…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Jee Seok Yoon , Kwanseok Oh , Yooseung Shin , Maciej A. Mazurowski , Heung-Il Suk

A dominant approach for addressing unsupervised domain adaptation is to map data points for the source and the target domains into an embedding space which is modeled as the output-space of a shared deep encoder. The encoder is trained to…

Machine Learning · Computer Science 2022-09-30 Mohammad Rostami

Open-set single-source domain generalization aims to use a single-source domain to learn a robust model that can be generalized to unknown target domains with both domain shifts and label shifts. The scarcity of the source domain and the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Pengkun Jiao , Na Zhao , Jingjing Chen , Yu-Gang Jiang

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

We are concerned with learning models that generalize well to different \emph{unseen} domains. We consider a worst-case formulation over data distributions that are near the source domain in the feature space. Only using training data from…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Riccardo Volpi , Hongseok Namkoong , Ozan Sener , John Duchi , Vittorio Murino , Silvio Savarese
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