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How does a cell self-organize so that its appendages attain specific lengths that are convenient for their respective functions? What kind of 'rulers' does a cell use to measure the length of these appendages? How does a cell transport…

Biological Physics · Physics 2021-08-31 Swayamshree Patra , Debashish Chowdhury

Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure inside the…

Biological Physics · Physics 2015-11-16 Pablo Sartori , Veikko Geyer , Andre Scholich , Frank Jülicher , Jonathon Howard

Many bacteria are motile by means of one or more rotating rigid helical flagella, making them the only known organism to use rotation as a means of propulsion. The rotation is supplied by the bacterial flagellar motor, a particularly…

We investigate the interfacial wave coupling dynamics in liquid metal batteries and their effects to the battery's operation safety. Similar to aluminum reduction cells, liquid metal batteries can be highly susceptible to…

Fluid Dynamics · Physics 2017-08-11 Gerrit Maik Horstmann , Norbert Weber , Tom Weier

In this fluid dynamics video, we demonstrate the microscale mixing enhancement of passive tracer particles in suspensions of swimming microalgae, Chlamydomonas reinhardtii. These biflagellated, single-celled eukaryotes (10 micron diameter)…

Run-and-tumble (RT) motion is commonly observed in flagellated microswimmers, arising from synchronous and asynchronous flagellar beating. One such example is a biflagellated alga, called \textit{Chlamydomonas reinhardtii}. Its flagellar…

Soft Condensed Matter · Physics 2025-10-17 Somnath Paramanick , Umashankar Pardhi , Harsh Soni , Nitin Kumar

Eukaryotic flagella are active structures with a complex architecture of microtubules, motor proteins and elastic links. They are capable of whiplike motions driven by motors sliding along filaments that are themselves constrained at an…

Soft Condensed Matter · Physics 2012-11-22 Raghunath Chelakkot , Arvind Gopinath , L. Mahadevan , Michael F. Hagan

The eukaryotic flagellum beats periodically, driven by the oscillatory dynamics of molecular motors, to propel cells and pump fluids. Small, but perceivable fluctuations in the beat of individual flagella have physiological implications for…

Cell Behavior · Quantitative Biology 2015-06-18 Rui Ma , Gary S. Klindt , Ingmar H. Riedel-Kruse , Frank Jülicher , Benjamin M. Friedrich

Many microswimmers are able to swim through viscous fluids by employing periodic non-reciprocal deformations of their appendages. Here we use a simple microswimmer model inspired by swimming biflagellates which consists of a spherical cell…

Soft Condensed Matter · Physics 2025-08-22 Sridhar Bulusu , Andreas Zöttl

The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

Many different microswimmers propel themselves using flagella that beat periodically. The shape of the flagellar beat and swimming speed have been observed to change with fluid rheology. We quantify changes in the flagellar waveforms of…

Fluid Dynamics · Physics 2025-02-25 Kelli E. Gutierrez , Becca Thomases , Paulo E. Arratia , Robert D. Guy

In nature, metachronal coordination is an efficient strategy for fluid pumping and self-propulsion. Yet, mimetic systems for this type of organization are scarce. Recently, metachronal motion was observed in a bead-based magnetocapillary…

Soft Condensed Matter · Physics 2023-11-07 Sebastian Ziegler , Megan Delens , Ylona Collard , Maxime Hubert , Nicolas Vandewalle , Ana-Sunčana Smith

Direct mechanical coupling is known to be critical for establishing synchronization among cilia. However, the actual role of the connections is still elusive - partly because controlled experiments in live samples are challenging. Here, we…

Soft Condensed Matter · Physics 2023-12-27 Yiming Xia , Zixian Hu , Da Wei , Ke Chen , Yi Peng , Mingcheng Yang

The course of a peritrichous bacterium such as E. coli crucially depends on the level of synchronization and self-organization of several rotating flagella. However, the rotation of each flagellum generates counter body movements which in…

Biological Physics · Physics 2015-11-11 Tapan Chandra Adhyapak , Holger Stark

Hair cells of the auditory and vestibular systems display astonishing sensitivity, frequency selectivity, and temporal resolution to external signals. These specialized cells utilize an internal active amplifier to achieve highly sensitive…

Neurons and Cognition · Quantitative Biology 2021-03-31 Justin Faber , Hancheng Li , Dolores Bozovic

The modeling of the beating of cilia and flagella in fluids is a particularly active field of study, given the biological relevance of these organelles. Various mathematical models have been proposed to represent the nonlinear dynamics of…

Soft Condensed Matter · Physics 2024-12-10 Irene Anello , François Alouges , Antonio De Simone

Cilia and flagella are hairlike organelles that propel cells through fluid. The active motion of the axoneme, the motile structure inside cilia and flagella, is powered by molecular motors of the dynein family. These motors generate forces…

Subcellular Processes · Quantitative Biology 2016-11-02 Pablo Sartori , Veikko Geyer , Jonathon Howard , Frank Jülicher

E. coli bacteria swim following a run and tumble pattern. In the run state all flagella join in a single helical bundle that propels the cell body along approximately straight paths. When one or more flagellar motors reverse direction the…

Soft Condensed Matter · Physics 2015-07-01 S. Bianchi , F. Saglimbeni , A. Lepore , R. Di Leonardo

We show that the flagellar beat of bull spermatozoa and Chlamydomonas Reinhardtii can be modelled by a minimal, geometrically nonlinear reaction-diffusion system. Model solutions are spatio-temporally animated patterns describing flagellar…

Biological Physics · Physics 2023-10-09 James F. Cass , Hermes Bloomfield-Gadelha

Cilia and flagella are hair-like extensions of eukaryotic cells which generate oscillatory beat patterns that can propel micro-organisms and create fluid flows near cellular surfaces. The evolutionary highly conserved core of cilia and…

Biological Physics · Physics 2015-05-13 Andreas Hilfinger , Amit K Chattopadhyay , Frank Julicher