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Deep Convolutional Neural Networks (CNNs) have been successfully used in many low-level vision problems like image denoising. Although the conditional image generation techniques have led to large improvements in this task, there has been…

Image and Video Processing · Electrical Eng. & Systems 2020-03-10 Ioannis Marras , Grigorios G. Chrysos , Ioannis Alexiou , Gregory Slabaugh , Stefanos Zafeiriou

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Minkyu Jeon , Rishwanth Raghu , Miro Astore , Geoffrey Woollard , Ryan Feathers , Alkin Kaz , Sonya M. Hanson , Pilar Cossio , Ellen D. Zhong

The cryo-electron microscope (cryo-EM) is increasingly popular these years. It helps to uncover the biological structures and functions of macromolecules. In this paper, we address image denoising problem in cryo-EM. Denoising the cryo-EM…

Computation · Statistics 2018-10-26 Yin Xian , Hanlin Gu , Wei Wang , Xuhui Huang , Yuan Yao , Yang Wang , Jian-Feng Cai

Generative adversarial networks (GANs) have gained considerable attention owing to their ability to reproduce images. However, they can recreate training images faithfully despite image degradation in the form of blur, noise, and…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Takuhiro Kaneko , Tatsuya Harada

Generative Adversarial Networks (GANs) have achieved state-of-the-art performance for several image generation and manipulation tasks. Different works have improved the limited understanding of the latent space of GANs by embedding images…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Christian Bartz , Joseph Bethge , Haojin Yang , Christoph Meinel

Electrical tomography techniques have been widely employed for multiphase-flow monitoring owing to their non invasive nature, intrinsic safety, and low cost. Nevertheless, conventional reconstructions struggle to capture fine details, which…

Image and Video Processing · Electrical Eng. & Systems 2025-12-23 Wejian Yan

Raman spectroscopy can provide insight into the molecular composition of cells and tissue. Consequently, it can be used as a powerful diagnostic tool, e.g. to help identify changes in molecular contents with the onset of disease. But robust…

Medical Physics · Physics 2023-08-02 Ciaran Bench , Mads S. Bergholt , Mohamed Ali al-Badri

We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network. We demonstrate the veracity of this deep learning-based super-resolution technique by inferring unresolved features in…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Kevin de Haan , Zachary S. Ballard , Yair Rivenson , Yichen Wu , Aydogan Ozcan

Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Yuxin Xie , Li Yu , Farhad Pakdaman , Moncef Gabbouj

Synthesizing high quality saliency maps from noisy images is a challenging problem in computer vision and has many practical applications. Samples generated by existing techniques for saliency detection cannot handle the noise perturbations…

Computer Vision and Pattern Recognition · Computer Science 2019-04-03 Prerana Mukherjee , Manoj Sharma , Megh Makwana , Ajay Pratap Singh , Avinash Upadhyay , Akkshita Trivedi , Brejesh Lall , Santanu Chaudhury

Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Paul Friedrich , Yannik Frisch , Philippe C. Cattin

Different tasks in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM) require enhancing the quality of the highly noisy raw images. To this end, we develop an efficient algorithm for signal enhancement of…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Guy Sharon , Yoel Shkolnisky , Tamir Bendory

Generative adversarial networks (GANs) are unsupervised Deep Learning approach in the computer vision community which has gained significant attention from the last few years in identifying the internal structure of multimodal medical…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Nripendra Kumar Singh , Khalid Raza

Cryogenic electron microscopy (cryo-EM) has become an enabling technology in drug discovery and in understanding molecular bases of disease by producing near-atomic resolution (less than 0.4 nm) 3D reconstructions of biological…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Hong Xu , David E. Timm , Shireen Y. Elhabian

Deep neural networks provide state-of-the-art performance for image denoising, where the goal is to recover a near noise-free image from a noisy observation. The underlying principle is that neural networks trained on large datasets have…

Information Theory · Computer Science 2019-04-09 Reinhard Heckel , Wen Huang , Paul Hand , Vladislav Voroninski

Cryogenic electron microscopy (cryo-EM) provides a unique opportunity to study the structural heterogeneity of biomolecules. Being able to explain this heterogeneity with atomic models would help our understanding of their functional…

It is widely accepted that medical imaging systems should be objectively assessed via task-based image quality (IQ) measures that ideally account for all sources of randomness in the measured image data, including the variation in the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Xichen Xu , Wentao Chen , Weimin Zhou

Real-world image noise removal is a long-standing yet very challenging task in computer vision. The success of deep neural network in denoising stimulates the research of noise generation, aiming at synthesizing more clean-noisy image pairs…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Zongsheng Yue , Qian Zhao , Lei Zhang , Deyu Meng

Determining the 3D structures of biological molecules is a key problem for both biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising technique for structure estimation which relies heavily on computational methods to…

Machine Learning · Statistics 2015-01-29 Ali Punjani , Marcus A. Brubaker