Related papers: Electron FLASH Delivery at Treatment Room Isocente…

Purpose: A diode EDGE Detector with a newly designed electrometer has been characterized for use in an UHDR electron beam and demonstrated appropriateness for UHDR FLASH radiotherapy dosimetry. Methods: Dose linearity, mean dose rate, and…

The injection of electrons into a laser wakefield accelerator (LWFA) is observed to generate an intense coherent ultra-broadband and ultrashort pulse radiation flash, consistent with the acceleration of electrons from rest to nearly the…

In order to dissipate long-lived radioactive waste, not only high ux proton accelerator but also electron linac have been proposed. A proton accelerator directly induces nuclear fission and mutation. On the other hand, electron beam has two…

Background: The normal tissue sparing effect of ultra-high dose rate irradiation (>40 Gy/s, UHDR), as compared to conventional dose rate (CONV), has attracted significant research interest for FLASH radiotherapy (RT). Accurate, dose rate…

The production of ultra-bright electron bunches using ionization injection triggered by two transversely colliding laser pulses inside a beam-driven plasma wake is examined via three-dimensional (3D) particle-in-cell (PIC) simulations. The…

In the context of the Lamb shift measurement in muonic helium we developed a thin-disk laser composed of a Q-switched oscillator and a multi-pass amplifier delivering pulses of 150 mJ at a pulse duration of 100 ns. Its peculiar requirements…

The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains challenging with several crucial aspects missing. This work…

The inability of conventional methods to completely remove the contaminants from pharmaceutical effluents led us to study the effect of Electron Beam (EB) irradiation on real pharmaceutical wastewater. In this paper, the samples from…

The aim of the FLASH linac is to create electron bunches of small transverse emittance and high current for the free electron laser facility FLASH at DESY. Available operational experience indicates that in order to optimize SASE signal at…

We report on the first experimental characterization of a laser-wakefield accelerator able to deliver, in a single pulse, doses in excess of \unit[1]{Gy} on timescales of the order of a hundred femtoseconds, reaching unprecedented average…

Ultrashort electron beams with femtosecond to picosecond bunch durations offer unique opportunities to explore active research areas ranging from ultrafast structural dynamics to ultra-high dose-rate radiobiological studies. We present a…

LINAC 4 is a normal conducting H- structure proposed to intensify the proton flux currently available for the CERN accelerator chain. This linac is designed to accelerate a 65 mA beam up to 160 MeV to be injected into the CERN Proton…

Within the framework of the LHC Injector Upgrade (LIU), the new LINAC4 is currently being commissioned to replace the existing LINAC2 proton source at CERN. After the expected completion at the end of 2016, the LINAC4 will accelerate H-…

Radiotherapy is part of the treatment of over 50% of cancer patients. Its efficacy is limited by the radiotoxicity to the healthy tissue. FLASH-RT is based on the biological effect that ultra-high dose rates (UHDR) and very short treatment…

Background: Use of a linear accelerator in ultra-high dose rate (UHDR) mode can provide a conduit for wider access to UHDR FLASH effects, sparing normal tissue, but care needs to be taken in the use of such systems to ensure errors are…

We present an experimental demonstration of high conversion efficiency Betatron x-ray radiation from petawatt laser irradiated near critical plasmas. Direct laser acceleration serves as the dominant regime when laser pulse of ~5e20 W/cm2…

We report the first in-air irradiations of biological samples with kHz laser-driven electrons with beam energy 20 MeV, high-energy tail extending to 40 MeV, and average dose rate up to 30 Gy/min. An in-house procedure has been developed to…

For the laser wakefield acceleration, suppression of beam energy spread while keeping sufficient charge is one of the key challenges. In order to achieve this, we propose bichromatic laser ionization injection with combined laser…

For injection of beams into circular machines with different horizontal and vertical emittance acceptance, the injection efficiency can be increased if these beams are flat, i.e. if they feature unequal transverse emittances. Generation of…

A dielectric-loaded linac powered by THz-pulses is one of the key parts of the "Attosecond X-ray Science: Imaging and Spectroscopy" (AXSIS) project at DESY, Hamburg. As in conventional accelerators, the AXSIS linac is designed to have phase…