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Related papers: PANDA: Processing-in-MRAM Accelerated De Bruijn Gr…

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In-memory database query processing frequently involves substantial data transfers between the CPU and memory, leading to inefficiencies due to Von Neumann bottleneck. Processing-in-Memory (PIM) architectures offer a viable solution to…

Deep Neural Networks (DNNs) have transformed the field of machine learning and are widely deployed in many applications involving image, video, speech and natural language processing. The increasing compute demands of DNNs have been widely…

Machine Learning · Computer Science 2021-08-17 Sourjya Roy , Mustafa Ali , Anand Raghunathan

Processing-in-memory (PIM) architecture is an inherent match for data analytics application, but we observe major challenges to address when accelerating it using PIM. In this paper, we propose Darwin, a practical LRDIMM-based multi-level…

Systems and Control · Electrical Eng. & Systems 2025-09-23 Donghyuk Kim , Jae-Young Kim , Wontak Han , Jongsoon Won , Haerang Choi , Yongkee Kwon , Joo-Young Kim

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing

Processing-in-memory (PIM) architectures have demonstrated great potential in accelerating numerous deep learning tasks. Particularly, resistive random-access memory (RRAM) devices provide a promising hardware substrate to build PIM…

Hardware Architecture · Computer Science 2022-02-01 Weidong Cao , Yilong Zhao , Adith Boloor , Yinhe Han , Xuan Zhang , Li Jiang

Processing in-memory (PIM) is promising to accelerate neural networks (NNs) because it minimizes data movement and provides large computational parallelism. Similar to machine learning accelerators, application mapping, which determines the…

Hardware Architecture · Computer Science 2024-07-02 Xuan Wang , Minxuan Zhou , Tajana Rosing

Genome analysis has revolutionized fields such as personalized medicine and forensics. Modern sequencing machines generate vast amounts of fragmented strings of genome data called reads. The alignment of these reads into a complete DNA…

Hardware Architecture · Computer Science 2024-11-22 Rotem Ben-Hur , Orian Leitersdorf , Ronny Ronen , Lidor Goldshmidt , Idan Magram , Lior Kaplun , Leonid Yavitz , Shahar Kvatinsky

Neural networks (NNs) are growing in importance and complexity. A neural network's performance (and energy efficiency) can be bound either by computation or memory resources. The processing-in-memory (PIM) paradigm, where computation is…

Hardware Architecture · Computer Science 2023-03-28 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Amirali Boroumand , Onur Mutlu

Dynamic programming (DP) algorithms, such as All-Pairs Shortest Path (APSP) and genomic sequence alignment, are fundamental to many scientific domains but are severely bottlenecked by data movement on conventional architectures. While…

Hardware Architecture · Computer Science 2026-03-02 Tsung-Han Lu , Weihong Xu , Tajana Rosing

With Von-Neumann computing architectures struggling to address computationally- and memory-intensive big data analytic task today, Processing-in-Memory (PIM) platforms are gaining growing interests. In this way, processing-in-DRAM…

Hardware Architecture · Computer Science 2019-04-12 Shaahin Angizi , Deliang Fan

Processing-in-Memory (PIM) enhances memory with computational capabilities, potentially solving energy and latency issues associated with data transfer between memory and processors. However, managing concurrent computation and data flow…

Hardware Architecture · Computer Science 2025-05-09 Ahmed Mamdouh , Haoran Geng , Michael Niemier , Xiaobo Sharon Hu , Dayane Reis

Various processing-in-memory (PIM) accelerators based on various devices, micro-architectures, and interfaces have been proposed to accelerate deep neural networks (DNNs). How to deploy DNNs onto PIM-based accelerators is the key to explore…

Hardware Architecture · Computer Science 2024-11-15 Xiaotian Sun , Xinyu Wang , Wanqian Li , Yinhe Han , Xiaoming Chen

Processing-in-memory (PIM) architectures are emerging to reduce data movement in data-intensive applications. These architectures seek to exploit the same physical devices for both information storage and logic, thereby dwarfing the…

Hardware Architecture · Computer Science 2023-05-09 Orian Leitersdorf , Ronny Ronen , Shahar Kvatinsky

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

Gene regulatory network reconstruction is a fundamental problem in computational biology. We recently developed an algorithm, called PANDA (Passing Attributes Between Networks for Data Assimilation), that integrates multiple sources of…

Quantitative Methods · Quantitative Biology 2017-04-18 Kimberly Glass , John Quackenbush , Jeremy Kepner

De novo assembly enables investigations of unknown genomes, paving the way for personalized medicine and disease management. However, it faces immense computational challenges arising from the excessive data volumes and algorithmic…

Hardware Architecture · Computer Science 2025-05-14 Heewoo Kim , Sanjay Sri Vallabh Singapuram , Haojie Ye , Joseph Izraelevitz , Trevor Mudge , Ronald Dreslinski , Nishil Talati

The performance and efficiency of running large-scale datasets on traditional computing systems exhibit critical bottlenecks due to the existing "power wall" and "memory wall" problems. To resolve those problems, processing-in-memory (PIM)…

Hardware Architecture · Computer Science 2022-04-22 Yinglin Zhao , Jianlei Yang , Bing Li , Xingzhou Cheng , Xucheng Ye , Xueyan Wang , Xiaotao Jia , Zhaohao Wang , Youguang Zhang , Weisheng Zhao

Modern Artificial Intelligence (AI) applications are increasingly utilizing multi-tenant deep neural networks (DNNs), which lead to a significant rise in computing complexity and the need for computing parallelism. ReRAM-based…

Emerging Technologies · Computer Science 2024-08-12 Bojing Li , Duo Zhong , Xiang Chen , Chenchen Liu

The widespread integration of embedded systems across various industries has facilitated seamless connectivity among devices and bolstered computational capabilities. Despite their extensive applications, embedded systems encounter…

Cryptography and Security · Computer Science 2024-04-16 Sreenitha Kasarapu , Sathwika Bavikadi , Sai Manoj Pudukotai Dinakarrao

Processing large-scale graph datasets is computationally intensive and time-consuming. Processor-centric CPU and GPU architectures, commonly used for graph applications, often face bottlenecks caused by extensive data movement between the…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-11 Marzieh Barkhordar , Alireza Tabatabaeian , Mohammad Sadrosadati , Christina Giannoula , Juan Gomez Luna , Izzat El Hajj , Onur Mutlu , Alaa R. Alameldeen
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