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Based on high-throughput dark-field full-field optical coherence tomography, we designed and built an OCT system that can measure a variety of samples with different scattered light intensities, such as materials with multi-layer…

Optics · Physics 2024-01-30 Youlong Fan , Qingye Hu , Zhongping Wang , Xiantao Wei , Zengming Zhang

Purpose: This study is to test the feasibility of optical coherence tomography (OCT) detection of photoreceptor abnormality and to verify the photoreceptor abnormality is rod predominated in early DR . Methods: OCT images were acquired from…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Taeyoon Son , Jennifer I. Lim , Xincheng Yao

Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise and bulk-motion noise, respectively. Because the cross-sectional retina has distinct features in OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jianlong Yang , Yan Hu , Liyang Fang , Jun Cheng , Jiang Liu

Optical coherence tomography (OCT) has become the most important imaging modality in ophthalmology. A substantial amount of research has recently been devoted to the development of machine learning (ML) models for the identification and…

To study whether it is possible to differentiate intermediate age-related macular degeneration (AMD) from healthy controls using partial optical coherence tomography (OCT) data, that is, restricting the input B-scans to certain pre-defined…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Danilo A. Jesus , Eric F. Thee , Tim Doekemeijer , Daniel Luttikhuizen , Caroline Klaver , Stefan Klein , Theo van Walsum , Hans Vingerling , Luisa Sanchez

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly…

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Open-set 3D macromolecule detection in cryogenic electron tomography eliminates the need for target-specific model retraining. However, strict VRAM constraints prohibit processing an entire 3D tomogram, forcing current methods to rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Ming-Yang Ho , Alberto Bartesaghi

The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease…

The Segment Anything Model (SAM) has gained significant attention in the field of image segmentation due to its impressive capabilities and prompt-based interface. While SAM has already been extensively evaluated in various domains, its…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Botond Fazekas , José Morano , Dmitrii Lachinov , Guilherme Aresta , Hrvoje Bogunović

With the introduction of spectral-domain optical coherence tomography (OCT), resulting in a significant increase in acquisition speed, the fast and accurate segmentation of 3-D OCT scans has become evermore important. This paper presents a…

Computer Vision and Pattern Recognition · Computer Science 2014-04-01 Fabian Rathke , Stefan Schmidt , Christoph Schnörr

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

The evaluation and monitoring of cells health in the human retina is crucial and follow time course of retinal diseases, detect lesions before irreversible visual loss and to evaluate treatment effects. Towards this goal, a major challenge…

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Major retinal layer segmentation methods from OCT images assume that the retina is flattened in advance, and thus cannot always deal with retinas that have changes in retinal structure due to ophthalmopathy and/or curvature due to myopia.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Tsubasa Konno , Takahiro Ninomiya , Kanta Miura , Koichi Ito , Noriko Himori , Parmanand Sharma , Toru Nakazawa , Takafumi Aoki

Retinal neovascularization (RNV) is a vision threatening development in diabetic retinopathy (DR). Vision loss associated with RNV is preventable with timely intervention, making RNV clinical screening and monitoring a priority. Optical…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Jinyi Hao , Jie Wang , Liqin Gao , Tristan T. Hormel , Yukun Guo , An-Lun Wu , Christina J. Flaxel , Steven T. Bailey , Kotaro Tsuboi , Thomas S. Hwang , Yali Jia

Linear optical operations are fundamental and significant for both quantum mechanics and classical technologies. We demonstrate a non-cascaded approach to perform arbitrary unitary and non-unitary linear operations for N-dimensional…

We show that with spatially incoherent illumination, the point spread function width of an imaging interferometer like that used in full-field optical coherence tomography (FFOCT) is almost insensitive to aberrations that mostly induce a…

Optics · Physics 2016-08-16 Peng Xiao , Mathias Fink , A. Claude Boccara

This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Bilal Hassan , Taimur Hassan , Ramsha Ahmed , Shiyin Qin , Naoufel Werghi