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The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Segmentation of tumors in brain MRI images is a challenging task, where most recent methods demand large volumes of data with pixel-level annotations, which are generally costly to obtain. In contrast, image-level annotations, where only…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Sergey Pavlov , Alexey Artemov , Maksim Sharaev , Alexander Bernstein , Evgeny Burnaev

New lesion segmentation is essential to estimate the disease progression and therapeutic effects during multiple sclerosis (MS) clinical treatments. However, the expensive data acquisition and expert annotation restrict the feasibility of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yicheng Wu , Zhonghua Wu , Hengcan Shi , Bjoern Picker , Winston Chong , Jianfei Cai

Whole brain segmentation on structural magnetic resonance imaging (MRI) is essential for understanding neuroanatomical-functional relationships. Traditionally, multi-atlas segmentation has been regarded as the standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Yunxi Xiong , Yuankai Huo , Jiachen Wang , L. Taylor Davis , Maureen McHugo , Bennett A. Landman

Tumor segmentation from magnetic resonance imaging (MRI) data is an important but time consuming manual task performed by medical experts. Automating this process is a challenging task because of the high diversity in the appearance of…

Computer Vision and Pattern Recognition · Computer Science 2013-12-24 Sudipta Roy , Sanjay Nag , Indra Kanta Maitra , Samir Kumar Bandyopadhyay

Magnetic resonance imaging (MRI) plays a vital role in the scientific investigation and clinical management of multiple sclerosis. Analyses of binary multiple sclerosis lesion maps are typically "mass univariate" and conducted with standard…

The slow acquisition speed of magnetic resonance imaging (MRI) has led to the development of two complementary methods: acquiring multiple views of the anatomy simultaneously (parallel imaging) and acquiring fewer samples than necessary for…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Anuroop Sriram , Jure Zbontar , Tullie Murrell , Aaron Defazio , C. Lawrence Zitnick , Nafissa Yakubova , Florian Knoll , Patricia Johnson

Precise characterization of stroke lesions from MRI data has immense value in prognosticating clinical and cognitive outcomes following a stroke. Manual stroke lesion segmentation is time-consuming and requires the expertise of neurologists…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Liang Shang , William A. Sethares , Anusha Adluru , Andrew L. Alexander , Vivek Prabhakaran , Veena A. Nair , Nagesh Adluru

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Segmentation of cardiac fibrosis and scar are essential for clinical diagnosis and can provide invaluable guidance for the treatment of cardiac diseases. Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been…

Image and Video Processing · Electrical Eng. & Systems 2021-07-01 Yinzhe Wu , Zeyu Tang , Binghuan Li , David Firmin , Guang Yang

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

The increasing prevalence of lumbar spinal canal stenosis has resulted in a surge of MRI (Magnetic Resonance Imaging), leading to labor-intensive interpretation and significant inter-reader variability, even among expert radiologists. This…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Arnesh Batra , Arush Gumber , Anushk Kumar

Accurate hippocampus segmentation in brain MRI is critical for studying cognitive and memory functions and diagnosing neurodevelopmental disorders. While high-field MRIs provide detailed imaging, low-field MRIs are more accessible and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Himashi Peiris , Zhaolin Chen

In many modern applications, a dependent functional response is observed for each subject over repeated time, leading to longitudinal functional data. In this paper, we propose a novel statistical procedure to test whether the mean function…

Methodology · Statistics 2024-01-17 Salil Koner , So Young Park , Ana-Maria Staicu

Automatic segmentation of brain glioma from multimodal MRI scans plays a key role in clinical trials and practice. Unfortunately, manual segmentation is very challenging, time-consuming, costly, and often inaccurate despite human expertise…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Minh H. Vu , Tufve Nyholm , Tommy Löfstedt

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

Accurate segmentation of brain tissue in magnetic resonance images (MRI) is a diffcult task due to different types of brain abnormalities. Using information and features from multimodal MRI including T1, T1-weighted inversion recovery…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Yongpei Zhu , Zicong Zhou , Guojun Liao , Qianxi Yang , Kehong Yuan

Multi-modal magnetic resonance imaging (MRI) is essential in clinics for comprehensive diagnosis and surgical planning. Nevertheless, the segmentation of multi-modal MR images tends to be time-consuming and challenging. Convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2019-08-07 Cheng Li , Hui Sun , Zaiyi Liu , Meiyun Wang , Hairong Zheng , Shanshan Wang